- Neurofibromatosis and Schwannoma Cases
- Ocular Oncology and Treatments
- Breast Implant and Reconstruction
- Meningioma and schwannoma management
- Reconstructive Facial Surgery Techniques
- Cerebrospinal fluid and hydrocephalus
- Infectious Diseases and Tuberculosis
- Eosinophilic Disorders and Syndromes
- Glioma Diagnosis and Treatment
- Neurological Disease Mechanisms and Treatments
- Muscle and Compartmental Disorders
- Alzheimer's disease research and treatments
- Venous Thromboembolism Diagnosis and Management
- Vasculitis and related conditions
- Inflammatory Myopathies and Dermatomyositis
- Bacterial Infections and Vaccines
- Hematological disorders and diagnostics
- CNS Lymphoma Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Dementia and Cognitive Impairment Research
- Hedgehog Signaling Pathway Studies
- Reconstructive Surgery and Microvascular Techniques
Massachusetts General Hospital
2022-2025
Harvard University
2024
University of California, San Francisco
2024
Creative Commons
2023
Objective: This study analyses the anatomy and sensory outcomes of targeted nipple areola complex reinnervation (TNR) in gender-affirming double incision mastectomy with free grafting (FNG). Background: TNR is a novel technique to preserve reconstruct intercostal nerves (ICN) improve postoperative sensation. There little evidence on relevant outcomes. Methods: 25 patients were prospectively enrolled. Data included demographics, surgical technique, axon/fascicle counts. Quantitative...
The locus coeruleus (LC) has been identified as a site that develops phosphorylated tau pathology earlier than cerebral cortex. We present data using high-resolution postmortem MRI and validated histopathology in controls the earliest Braak (BB) stages (BBI-BBII) LC. ex vivo provides 3D volume (quantitative), while histology reveals specificity severity burden (semi-quantitative). mapped our highly regionally specific LC onto reconstructions of same samples used (n = 11). noted significant...
The authors describe the clinical, histologic, and serologic findings of a patient with necrotizing myositis extraocular muscles in setting antisynthetase syndrome, as well subsequent management. This is first case literature systemic to have associated ophthalmic findings.
Mass lesions within the insular are diagnostically and surgically challenging due to numerous critical cortical, subcortical, vascular structures surrounding region. Two main surgical techniques - transsylvian approach transcortical provide access cortex. Of range of pathologies encountered, abscesses in insula surprisingly rare.A 34-year-old patient was admitted for resection a suspected high-grade glioma dominant hemisphere. A rapid clinical decline prompted emergent neurosurgical...
A 68-year-old man without a medical history developed 2 months of progressive weakness and cervicalgia. Examination showed quadriparesis with T10 sensory level. Spine MRI revealed an expansile intramedullary lesion from obex to T11 peripheral nodular enhancement (Figure, A–D). Brain MRI, body PET/CT, broad serum diagnostics were normal (eTable 1, [links.lww.com/WNL/C653][1]). CSF protein 2,505 mg/dL, 0 cells/μL, glucose 88 cell-free DNA sequencing identified pathogenic variant in TERT...
BACKGROUND: Gender-affirming mastectomy is the most frequently performed procedure in patients transitioning from a woman to man. However, standard surgical approach, intercostal nerves (INC) are transected which may result loss of sensation. Targeted nipple areola complex (NAC) reinnervation (TNR) gender-affirming double incision with free grafts (FNG) aims improve postoperative The TNR technique involves preservation lateral ICN, and coaptation NAC. A comprehensive understanding relevant...