A5011563198- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Microscopic Colitis
- Inflammatory Bowel Disease
- Venous Thromboembolism Diagnosis and Management
- Drug-Induced Hepatotoxicity and Protection
- Alcohol Consumption and Health Effects
- Helicobacter pylori-related gastroenterology studies
- Hormonal and reproductive studies
- Systemic Sclerosis and Related Diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Eosinophilic Esophagitis
- Interprofessional Education and Collaboration
- Patient-Provider Communication in Healthcare
- Acute Ischemic Stroke Management
- Healthcare Systems and Technology
- Pharmacogenetics and Drug Metabolism
Box Hill Hospital
2024
Eastern Health
2023-2024
London North West Healthcare NHS Trust
2016-2020
Ealing Hospital
2016
Summary Background Reports of DILI due to herbal and dietary supplements have been increasing over time. Aims To characterise clinical, laboratory histopathological phenotypes outcomes drug‐induced liver injury (DILI) anabolic‐androgenic steroids (AAS), selective androgen receptor modulators (SARMs), bodybuilding (BBS) in Australia. Methods Retrospective case series. Patients presented nine Australian tertiary hospitals, 2017–2023. was defined biochemically patients were included if their...
Abstract Background Serum free thiols (SFTs) reflecting oxidative stress appear to correlate with inflammatory bowel disease (IBD) activity. We aimed evaluate the performance of SFTs concentrations vs endoscopic and histological activity, compare established biomarkers, identify clinical laboratory parameters independently associated SFT levels in IBD patients. Methods Patients confirmed undergoing routine ileocolonoscopy for activity assessment were prospectively recruited, serum samples...
Abstract Background and Aim The rising incidence of hepatocellular carcinoma (HCC) in Australia is related to increasing rates metabolic‐associated fatty liver disease (MAFLD). This study aimed prospectively characterize the metabolic profile, lifestyle, biometric features, response treatment HCC patients an Australian population. Method Multicenter prospective cohort analysis newly diagnosed at six multidisciplinary team meetings over a 2‐year period. Results Three hundred thirteen (313)...
The optimal treatment approach in very-early and early-stage hepatocellular carcinoma (HCC) is not precisely defined, there ambiguity the literature around comparative efficacy of surgical resection versus ablation as curative therapies for limited disease. We performed this real-world propensity-matched, multi-centre cohort study to assess differences survival outcomes between those undergoing receiving ablation. Patients with Barcelona Clinic Liver Cancer (BCLC) 0/A HCC first diagnosed 1...
The management of early-stage hepatocellular carcinoma (HCC) is complex, with multiple treatment strategies available. There a paucity literature regarding variations in the patterns care and outcomes between transplant non-transplant centres. We conducted this real-world multi-centre cohort study two liver cancer referral centres an integrated program additional eight HCC across Australia to identify variation key survival outcomes. Patients stage Barcelona Clinic Liver Cancer (BCLC) 0/A...
Background: Faecal biomarkers are increasingly utilized for disease assessment in inflammatory bowel (IBD). Objectives: To characterize the relative and combined accuracy of faecal calprotectin (FC) immunochemical testing (FIT) detecting endoscopic histologically active Crohn’s (CD) ulcerative colitis (UC), subdivided by location. Design: A prospective cohort study. Methods: Patients with confirmed IBD undergoing routine ileocolonoscopy activity were prospectively recruited performed both FC...
Percutaneous ablation is recommended in Barcelona Clinic Liver Cancer (BCLC) stage 0/A patients with HCC ≤3 cm as a curative treatment modality alongside surgical resection and liver transplantation. However, trans-arterial chemo-embolisation (TACE) commonly used the real-world an initial single small contrast to widely accepted clinical practice guidelines which typically describe TACE for intermediate-stage HCC. We performed this propensity-matched multi-centre cohort study ≤ 3 assess...
<h3></h3> Retention of medical information is often poor, especially when patients or parents are anxious. Patients focus on diagnosis-related and fail to register instructions treatment. improved with written information. Patient experience feedback was collected using visual aids engage patients. Communication highlighted as an area for improvement. We present the use bedside patient-led (Comms) charts improve communication between patients, staff. This tool implemented a district general...
<h3>Introduction and Objectives</h3> Prognostic accuracy clinical utility of the Pulmonary Embolism Severity Index (PESI) & simplified PESI (sPESI) at predicting very early mortality (<7 days) has not been previously investigated. We use this time frame to suggest outpatient imaging could be used confirm a suspected pulmonary embolism (PE). <h3>Methods</h3> A retrospective chart review adult patients (≥18 years), who presented two emergency departments, January 2013 – December 2015,...
Emergency Medicine, St George Hospital, Sydney, Australia