A5023191603- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Health and Technologies
- Prenatal Screening and Diagnostics
- Ovarian function and disorders
- Birth, Development, and Health
- Gynecological conditions and treatments
- Mitochondrial Function and Pathology
- Ectopic Pregnancy Diagnosis and Management
- Reproductive Health and Contraception
- Uterine Myomas and Treatments
- S100 Proteins and Annexins
- Inflammatory mediators and NSAID effects
- Molecular Biology Techniques and Applications
- Congenital Heart Disease Studies
- Sperm and Testicular Function
- Redox biology and oxidative stress
- COVID-19 Impact on Reproduction
- Opioid Use Disorder Treatment
- Sexual Differentiation and Disorders
- Prenatal Substance Exposure Effects
- Medical History and Research
- Entrepreneurship Studies and Influences
- Cystic Fibrosis Research Advances
- Single-cell and spatial transcriptomics
Beth Israel Deaconess Medical Center
2017-2024
Harvard University
2017-2024
Boston IVF
2017-2024
University of Alaska Anchorage
2022
Memorial Sloan Kettering Cancer Center
2019
Hadassah Medical Center
2018
Beth Israel Deaconess Hospital
2017
RELX Group (United States)
2017
RELX Group (Netherlands)
2017
Washington University in St. Louis
2014-2016
What is the treatment path and cumulative live birth (CLB) rate from a single oocyte retrieval of patients who intend to pursue PGT-A at start an IVF cycle compared matched controls?The choice first decreases CLB per for <38 years age, however ≥38 age benefit significantly embryo transfer (ET) when (LB) evaluated.PGT-A has been shown reduce practice transferring multiple embryos confer higher transfer.This retrospective cohort study December 2014 September 2016, involving 600 patients: those...
Abstract STUDY QUESTION Does fluorescence lifetime imaging microscopy (FLIM)-based metabolic assessment of human blastocysts prior to frozen transfer correlate with pregnancy outcomes? SUMMARY ANSWER FLIM failed distinguish consistent patterns in mitochondrial metabolism between leading compared those that did not. WHAT IS KNOWN ALREADY measurements provide quantitative information on NAD(P)H and flavin adenine dinucleotide (FAD+) concentrations. The embryos has long been linked their...
Importance Poor ovarian response (POR) to stimulation may impact patients’ desire or need utilize cryopreserved oocytes for family building in the future. These findings, captured by Society Assisted Reproductive Technology (SART) national data, underscore tailored counseling and further research into decision-making processes influencing oocyte utilization. Objective To examine association of number vitrified with likelihood timing patients returning utilization following planned...
Analyzing data on ART presents unique and sometimes complicated challenges related to choosing the unit(s) of analysis statistical model. In this commentary, we provide examples how these arise guidance for overcoming them. We discuss implications different ways count treatment cycles, considering perspectives research questions, management patient counseling. present advantages disadvantages models, finally, definition calculation cumulative incidence live birth, which is a key outcome ART.
ObjectiveTo study the impact of routine ketorolac administration during oocyte retrieval on proportion patients who require postoperative narcotics for analgesia.DesignRetrospective cohort study.SettingSingle, university-affiliated infertility clinic.Patient(s)All women undergoing between July and November 2016 (non-ketorolac group [NKG]; n = 826) April-August 2017 (ketorolac group, KG; 1780).Intervention(s)A single 30 mg intravenous dose was administered after procedure.Main outcome...
Central neurons undergo cell death after axotomy. One of the signaling pathways for this process is oxidative modification one or more critical sulfhydryls in association with superoxide generation within mitochondria. Agents that reduce oxidized are neuroprotective axotomized retinal ganglion cells, and we hypothesized occurs via reversal effects mitochondrial-produced superoxide. To study this, measured ability novel borane-phosphine complex drugs bis(3-propionic acid methyl...