Junhu Yao

ORCID: 0000-0002-0848-8392
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About
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Research Areas
  • Ruminant Nutrition and Digestive Physiology
  • Gut microbiota and health
  • Reproductive Physiology in Livestock
  • Genetic and phenotypic traits in livestock
  • Animal health and immunology
  • Clostridium difficile and Clostridium perfringens research
  • Milk Quality and Mastitis in Dairy Cows
  • Probiotics and Fermented Foods
  • MicroRNA in disease regulation
  • Immune Response and Inflammation
  • Infant Nutrition and Health
  • Microbial Metabolites in Food Biotechnology
  • Extracellular vesicles in disease
  • Animal Nutrition and Physiology
  • Phytase and its Applications
  • Bioenergy crop production and management
  • Food composition and properties
  • Nitrogen and Sulfur Effects on Brassica
  • Diet, Metabolism, and Disease
  • Breastfeeding Practices and Influences
  • Agriculture, Soil, Plant Science
  • Liver Disease Diagnosis and Treatment
  • Escherichia coli research studies
  • Barrier Structure and Function Studies
  • Gout, Hyperuricemia, Uric Acid

Northwest A&F University
2016-2025

Agriculture and Forestry University
2023

Abstract Background The increased growth rate of young animals can lead to higher lactation performance in adult goats; however, the effects ruminal microbiome on goats, and contribution early-life rumen lifelong goats has not yet been well defined. Hence, this study assessed with different average daily gains (ADG) evaluated its during first period. Results Based monitoring a cohort 99 from youth lactation, 15 highest ADG (HADG) lowest (LADG) were subjected fluid metabolome profiling....

10.1186/s40168-023-01652-5 article EN cc-by Microbiome 2023-09-29

Abstract Ruminal microbiota changes frequently with high grain diets and the occurrence of subacute ruminal acidosis (SARA). A grain-induced goat model SARA, durations a significant decrease in rumen pH value to less than 5.6 an increase lipopolysaccharides concentration, is constructed for real-time monitoring bacteria alteration. Using 16 S rRNA gene sequencing, bacterial differences between goats from SARA healthy groups are identified at every hour six continuous hours after feeding....

10.1038/s41522-021-00215-6 article EN cc-by npj Biofilms and Microbiomes 2021-05-14

Abstract Background Due to the high prevalence and complex etiology, bovine mastitis (BM) is one of most important diseases compromise dairy cow health milk quality. The shift in compositions has been widely investigated during mastitis, but recent studies suggested that gastrointestinal microorganism also a crucial effect on inflammation other peripheral tissues organs, including mammary gland. However, research focused variation rumen inner-environment still limited. Therefore, ruminal...

10.1186/s40104-020-00543-1 article EN cc-by Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2021-02-08

Rumen microbes play an important role in ruminant energy supply and animal performance. Previous studies showed that yak (Bos grunniens) rumen microbiome fermentation differ from other ruminants. However, little is understood about the features of make adapted to their unique environmental dietary conditions. This study was investigate metabolome understand how adapt coarse forage harsh environment Qinghai-Tibetan plateau. Nine female Qaidam yellow cattle taurus), 9 dzomo (hybrids yak)...

10.1016/j.aninu.2022.07.014 article EN cc-by-nc-nd Animal nutrition 2022-08-09

Previous studies have demonstrated that Lactobacillus has anti-inflammatory properties, but the protective functions of and mechanisms inhibition necrotic enteritis (NE) in intestines chickens not been fully clarified. In present study, we selected a probiotic strain, fermentum 1.2029, which good adhesive ability high survival rate low pH bile salts. The objective this study was to examine properties L. 1.2029 against NE chickens. Two hundred forty 1-d-old male Arbor Acres broilers were...

10.3382/ps.2012-02548 article EN cc-by-nc-nd Poultry Science 2012-11-15

Milk can mediate maternal-neonatal signal transmission by the bioactive component extracellular vesicles (EVs), which select specific types of miRNA to encapsulate. The profiling sheep milk EVs was characterized sequencing and compared with that cow milk. Nanoparticle tracking analysis revealed concentration 1.3 ± 0.09 × 10

10.3390/ani10020331 article EN cc-by Animals 2020-02-20

The rumen, which contains a series of prokaryotes and eukaryotes with high abundance, determines the ability to degrade complex carbohydrates in ruminants. Using 16S rRNA gene sequencing, we compared ruminal microbiota dairy goats that foregut colon mice found more Bacteroides identified helps ruminants utilize plant-derived polysaccharides, cellulose, other structural carbohydrates. Furthermore, high-fiber diets did not significantly increase intestinal fiber-degrading bacteria mice, but...

10.1128/spectrum.00446-22 article EN cc-by Microbiology Spectrum 2022-08-04

The transition from pregnancy to lactation is critical in dairy cows. Among others, cows experience a metabolic stress due large change glucose and lipid metabolism. Recent studies revealed that bile acids (BA), besides being involved both the emulsification solubilization of fats during intestinal absorption, can also affect metabolism lipids, directly or indirectly by affecting gut microbiota. Thus, we used untargeted targeted metabolomics 16S rRNA sequencing approaches investigate...

10.3168/jds.2024-24658 article EN cc-by Journal of Dairy Science 2024-06-20

The objective of this study was to evaluate the effects physically effective NDF (peNDF) in goat diets containing alfalfa hay as sole forage source on feed intake, chewing activity, ruminal fermentation, and nutrient digestibility. Four rumen-fistulated goats were fed different proportions chopped ground a 4 × Latin square design. Diets chemically similar but varied peNDF content: low, moderate high, high. Dietary content determined using Penn State Particle Separator with 2 sieves (8 19 mm)...

10.2527/jas.2010-3013 article EN Journal of Animal Science 2010-10-09

Abstract The impact of dietary fibers on lipid digestion within the gastrointestinal tract depends their molecular and physicochemical properties. In this study, influence electrical characteristics ability to interfere with protein‐coated droplets was investigated using an in vitro small intestine model. Three were examined: cationic chitosan; anionic alginate; neutral locust bean gum (LBG). particle size, ζ‐potential, microstructure, apparent viscosity β‐lactoglobulin stabilized...

10.1111/1750-3841.13361 article EN Journal of Food Science 2016-06-14

Mastitis is generally considered a local inflammatory disease caused by the invasion of exogenous pathogens and resulting in dysbiosis microbiota metabolites milk. However, entero-mammary pathway theory may establish possible link between some endogenous gut bacteria occurrence development mastitis. In current study, we attempted to investigate differences profile metabolite composition serum from healthy cows those with subclinical mastitis clinical Compared cows, microbial community...

10.3168/jds.2021-21654 article EN cc-by Journal of Dairy Science 2022-08-02

In rumen fermentation, fumaric acid (FA) could competitively utilize hydrogen with methanogenesis to enhance propionate production and suppress methane emission, but both effects were diet-dependent. This study aimed explore the of FA supplementation on fermentation in goats fed diets varying forage concentrate particle size. Four rumen-cannulated used a 4 × Latin square design 2 factorial arrangement treatments: low or high ratio size: size (Fps:Cps), without (24 g/d). Fps:Cps was higher...

10.1186/s40104-018-0235-3 article EN cc-by Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology 2018-02-05

Understanding the altered gastrointestinal microbiota is important to illuminate effects of maternal grazing (MG: maternally nursed and grazed) barn feeding (BF: supplied milk replacer, starter feed, alfalfa hay) on performance immune function yak calves. Compared with MG group, significantly increased body weight, height, length, chest girth, organ development liver, spleen, thymus were identified in BF which resulted from dry matter intake, concentrations propionate, butyrate, isobutyrate,...

10.3389/fmicb.2020.00485 article EN cc-by Frontiers in Microbiology 2020-04-03

The present study aims to evaluate the effects of different early weaning paradigms, which supplied with extra alfalfa hay, or starter feeding, both hay and along milk replacer, on gastrointestinal microbial community, growth, immune performance yak calves. Twenty 30-day-old male calves were randomly assigned four groups, including control (CON), (A), feeding (S), plus (SA) groups. colonization, development function, growth all separately measured. Supplementation during pre-weaning period...

10.3389/fmicb.2020.00994 article EN cc-by Frontiers in Microbiology 2020-06-04

Mastitis affects almost all mammals including humans and dairy cows. In the industry, bovine mastitis is a disease with persistently high incidence, causing serious losses to health of cows, quality products, economy farms. Although local udder infection caused by invasion exogenous pathogens into mammary gland was considered main cause mastitis, evidence has been established continues grow, showing that nutrition factors gastrointestinal microbiome (GM) as well their metabolites are also...

10.1016/j.aninu.2024.01.010 article EN cc-by-nc-nd Animal nutrition 2024-03-16

Abstract The ruminal microbiota generates biogenic methane in ruminants. However, the role of host genetics modifying microbiota‐mediated emissions remains mysterious, which has severely hindered emission control this notorious greenhouse gas. Here, we uncover genetic basis rumen microorganisms by genome‐ and transcriptome‐wide association studies with matched genome, transcriptome, microbiome data from a cohort 574 Holstein cattle. Heritability estimation revealed that approximately 70%...

10.1002/imt2.234 article EN cc-by iMeta 2024-09-03

The internal environment of the cow's udder directly affects health and milk quality. 16S rDNA sequencing liquid chromatography–mass spectrometry (LC–MS) methods were used to investigate significant differences in microbial diversity metabolites among cows that are healthy (H) those suffering from subclinical mastitis (SM) clinical (CM). Results uncovered more than 16 192 differently abundant microbiota at phylum genus levels, respectively, 673 different levels enriched 20 pathways 3 groups....

10.1021/acs.jafc.0c03738 article EN Journal of Agricultural and Food Chemistry 2020-07-06
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