A5015850702- Cerebral Palsy and Movement Disorders
- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- Genomics and Rare Diseases
- Pneumonia and Respiratory Infections
- HIV, Drug Use, Sexual Risk
- Neurogenetic and Muscular Disorders Research
- Infant Development and Preterm Care
- Family and Disability Support Research
- Metabolism and Genetic Disorders
- Neonatal and fetal brain pathology
- Mobile Health and mHealth Applications
- Birth, Development, and Health
- Virology and Viral Diseases
- Congenital Anomalies and Fetal Surgery
- Health, Environment, Cognitive Aging
- HIV/AIDS drug development and treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Focus Groups and Qualitative Methods
- Breastfeeding Practices and Influences
- Tuberculosis Research and Epidemiology
- Bacterial Infections and Vaccines
- Pregnancy and preeclampsia studies
- Cardiac Structural Anomalies and Repair
McGill University Health Centre
2013-2025
McGill University
2013-2021
Background In South Africa, stigma, discrimination, social visibility and fear of loss confidentiality impede health facility-based HIV testing. With 50% adults having ever tested for in their lifetime, private, alternative testing options are urgently needed. Non-invasive, oral self-tests offer a potential confidential, unsupervised self-testing option, but global data limited. Methods A pilot cross-sectional study was conducted from January to June 2012 care workers based at the University...
Cerebral palsy (CP) is the most prevalent physical disability in children and often accompanied by other neurodevelopmental disorders (NDDs) such as attention deficit hyperactivity disorder (ADHD). Both conditions are influenced genetic environmental factors significantly affect daily functioning. This study aims to estimate prevalence of ADHD school-aged with CP from a large, population-based registry explore associated including sex, material social deprivation, epilepsy, prematurity,...
Background Implementation of human immunodeficiency virus rapid and point-of-care tests (RDT/POCT) is understood to be impeded by many different factors that operate at 4 main levels—test devices, patients, providers, health systems—yet a knowledge gap exists how they act interact impede implementation. To fill this gap, with view improving the quality implementation, we conducted systematic review. Methods Five databases were searched, 16,672 citations retrieved, data abstracted on 132...
To assess the stability of Gross Motor Functional Classification System (GMFCS) in children with cerebral palsy (CP) from time preliminary diagnosis (~2 years age) to (~5 age), and examine factors associated reclassification.We conducted a longitudinal study using sample Canadian CP Registry. Stability was analysed by percentage agreement between timepoints weighted prevalence bias adjusted kappa statistic. Univariate multivariate logistic regressions were performed identify variables...
Multiplexed point-of-care (POC) devices can rapidly screen for HIV-related co-infections (eg, hepatitis C (HCV), B (HBV), syphilis) in one patient visit, but global evidence this approach remains limited. This study aimed to evaluate a multiplex POC testing strategy expedite screening at-risk populations.A was developed with two subsequent versions of an investigational device Miriad. It evaluated non-comparable settings and populations countries feasibility conduct, detection new...
Keywords: Diagnostics and development studies, global health application, impact, low middle income countries, personalized medicine, point-of-care tests.
<h3>Background</h3> South Africa has about 11% of the total population living with HIV, largest to date for any country. Facility-based HIV testing reached only 50% Africans because fear visibility leading stigma, embarrassment and discrimination. Alternative strategies like self-testing may improve engagement, but evidence is limited. For be successful, knowledge regarding process, clear instructions how conduct, interpret seek linkages counselling staging essential. <h3>Methods</h3> We...
Parental nativity, as well duration of residence foreign-born parents in the host country, has been shown to be associated with size at birth. However, most studies have focused on maternal nativity status only and not accounted for important characteristics both parents.To explore whether paternal length (LOR) are independently birthweight gestational age a representative sample infants Canada.We compared mean differences sex- age-standardised z-score by nationally 130,532 singleton born...
<h3>Objective:</h3> To capture the full extent of genomic contributions to cerebral palsy (CP) in an unselected cohort. <h3>Background:</h3> CP is most common childhood physical disability. It increasingly recognized that changes can contribute at least some clinical features and phenotypes individuals with . The uncovering rare variants result a degree diagnostic confusion, known disorders labeled as "mimics". This has led debate about validity diagnosis "genetic diagnosis". Resolution...