A5021536655- Mental Health Research Topics
- Heart Rate Variability and Autonomic Control
- Functional Brain Connectivity Studies
- Treatment of Major Depression
- Neural and Behavioral Psychology Studies
- Stress Responses and Cortisol
- Personality Disorders and Psychopathology
- Psychotherapy Techniques and Applications
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Resilience and Mental Health
- Memory and Neural Mechanisms
- Identity, Memory, and Therapy
- Child and Adolescent Psychosocial and Emotional Development
- Psychological and Temporal Perspectives Research
- Autism Spectrum Disorder Research
- Face Recognition and Perception
- Epigenetics and DNA Methylation
- Attention Deficit Hyperactivity Disorder
- Biochemical effects in animals
- Obsessive-Compulsive Spectrum Disorders
- Prenatal Substance Exposure Effects
- Neuroendocrine regulation and behavior
- ECG Monitoring and Analysis
- Birth, Development, and Health
- Digital Mental Health Interventions
Max Planck Institute of Psychiatry
2020-2024
University of Vienna
2018
<b><i>Introduction:</i></b> Schema therapy (ST) reduces depressive symptoms, but clinical trials have not investigated its effectiveness for patients suffering from severe forms of depression and high rates comorbidities. There is demand exploring improving treatments this patient group. The objective the current study was to evaluate whether ST more effective than individual supportive (IST) noninferior compared with cognitive behavioral (CBT) in treating depression....
Abstract The prefrontal cortex is a key player in stress response regulation. Electroencephalographic (EEG) responses, such as decrease frontal alpha and an increase beta power, have been proposed to reflect stress‐related brain activity. However, the likely composed of different parts cognitive effort, time pressure, social‐evaluative threat, which not distinguished previous studies. This distinction, however, crucial if we aim establish reliable tools for early detection conditions...
Our study focused on the general population and explored relationships between autistic traits alexithymia, one hand, related to depression, anxiety, stress, other, using a multivariate statistical approach. In previous research, alexithymia have been linked these both in clinical populations population. We also investigated possible multiplicative effect of attempted determine which two variables is better predictor for health outcomes.An online survey was conducted, 302 participants were...
Abstract Background Major depressive disorder represents (MDD) a major cause of disability and disease burden. Beside antidepressant medication, psychotherapy is key approach treatment. Schema therapy has been shown to be effective in the treatment psychiatric disorders, especially personality variety settings patient groups. Nevertheless, there no evidence on its effectiveness for MDD an inpatient nor day clinic setting little known about factors that drive response such target group....
The diameter of the human pupil tracks working memory processing and is associated with activity in frontoparietal network. At same time, recent neuroimaging research has linked fluctuations to salience In this combined functional magnetic resonance imaging (fMRI)/pupillometry study, we recorded size healthy participants while they performed a blockwise organized task (N-back) inside an MRI scanner order monitor neural during processing. We first confirmed that mean closely followed load....
Abstract Major depressive disorder (MDD) is a devastating and heterogenous for which there are no approved biomarkers in clinical practice. We recently identified anticipatory hypo-arousal indexed by pupil responses as candidate mechanism subserving depression symptomatology. Here, we conducted replication extension study of these findings. analyzed sample 40 unmedicated patients with diagnosis 30 healthy control participants, who performed reward anticipation task while were measured. Using...
Early adaptive schemas (EAS) are resilience-oriented counterparts to early maladaptive (EMS), which central in schema therapy. The Young Positive Schema Questionnaire (YPSQ) was developed as a measure of EAS but has been evaluated neither relation clinical population nor German-speaking sample. Objectives this study were therefore the psychometric validation German YPSQ community sample and comparison psychiatric patients. Participants 1,418 individuals from 182 patients with main diagnosis...
Early life adversity and psychiatric disorders are associated with earlier declines in neurocognitive abilities during adulthood. These may be preceded by changes biological aging, specifically epigenetic age acceleration, providing an opportunity to uncover genome-wide biomarkers that identify individuals most likely benefit from early screening prevention.
Abstract Major depressive disorder (MDD) has been related to abnormal amygdala activity during emotional face processing. However, a recent large-scale study ( n = 28,638) found no such correlation, which is probably due the low precision of fMRI measurements. To address this issue, we used simultaneous and eye-tracking measurements commonly employed recognition task. Eye-tracking provide high-precision data, can be enrich potentially stabilize readouts. With behavioral response,...
Abstract Abnormalities in the neural mechanisms of stress response have potential to serve as a transdiagnostic marker for stress-related disorders. This is rooted highly individual and dynamic response, which poses challenge classical experimentally informed models that focus on specific phases, conditions, or stimuli during task. Here, we integrate heart rates (HR) an immanent index stress-response combine these with functional magnetic resonance imaging (fMRI) data. In this study, 83...
Early Adaptive Schemas (EAS) are resilience-oriented counterparts to Maladaptive (EMS), which central in Schema Therapy. The Young Positive Questionnaire (YPSQ) was developed as a measure of 14 EAS. YPSQ not yet evaluated relation clinical population and has been validated German. Objectives the present study were therefore psychometric validation German community sample comparison EAS psychiatric patients. Participants 1,418 individuals from 182 patients with main diagnosis Major Depressive...