- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Vitamin D Research Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Paraoxonase enzyme and polymorphisms
- Pancreatitis Pathology and Treatment
- Thyroid Disorders and Treatments
- Cardiovascular Disease and Adiposity
- Inflammatory Biomarkers in Disease Prognosis
- Apelin-related biomedical research
- Systemic Sclerosis and Related Diseases
- Renal and Vascular Pathologies
- Renal Diseases and Glomerulopathies
- Liver Disease Diagnosis and Treatment
- Parathyroid Disorders and Treatments
- Neuroendocrine Tumor Research Advances
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Bariatric Surgery and Outcomes
- Mycobacterium research and diagnosis
- Eosinophilic Esophagitis
- Muscle and Compartmental Disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Neuroblastoma Research and Treatments
Biruni University
2015-2023
Sağlık Bilimleri Üniversitesi
2019
Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi
2012-2019
İstanbul Eğitim ve Araştırma Hastanesi
2014
Şişli Etfal Eğitim ve Araştırma Hastanesi
2001-2004
Purpose: We aimed to study the inflammatory parameters of complete blood count in breast cancer cases. Materials and Methods: This retrospective covered 178 patients 107 age body mass index matched healthy women. Complete parameters, neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte (PLR) MPV/platelet were analyzed. Results: The leukocyte, neutrophil higher patient group (p values 0.001, 0.0001 0.0001, respectively) while haemoglobin hematocrit control (p=0.0001 for both). Logistic...
Leptospirosis is an infectious disease caused by pathogenic leptospires and may vary in degree from asymptomatic infection to severe fatal illness. Sixteen patients (all males; aged 40+/-17 years) with leptospirosis were admitted Sişli Etfal Training Research Hospital between July 1998 August 2003 retrospectively reviewed. Age, gender, occupation, clinical presentation, laboratory features, seasonal distribution of the disease, diagnostical approach, prognostic factors evaluated. Eleven...
<b><i>Background: </i></b>The natural history of AA amyloidosis is typically progressive, leading to multiple organ failure and death. We analyzed the etiology as well clinical laboratory features patients with biopsy-proven evaluated ultimate outcome. <b><i>Methods: </i></b>Seventy-three (24 female; mean age 41.85±15.89 years) were retrospectively. Demographic, studied outcome was assessed. <b><i>Results:...
OBJECTIVE:In this study, we aimed to compare the cardiovascular risk factors that might be associated with inflammation, atherosclerosis and metabolic syndrome between hemodialysis peritoneal dialysis patients.METHODS: Fifty 50 patients who had been receiving therapy for at least one year were included in study.Venous blood samples taken after 12 hours of fasting, serum glucose, triglyceride, low-density lipoprotein (LDL)-cholesterol, high-density (HDL)-cholesterol, C-reactive protein,...
Objective. To investigate the anti proteinuric effect of pentoxifylline in diabetic patients, we prospectively studied 25 hypertensive type 2 patients with persistent microalbuminuria and normal renal function impact combining an angiotensin converting enzyme inhibitor, lisinopril, on urinary albumin excretion compared results those obtained a control group treated lisinopril only. Material Methods. Fifty (31 males 19 females, aged between 47–73 years) were randomly assigned to two groups....
Hepatitis C virus (HCV) infection has recently become the major cause of chronic liver disease among patients on hemodialysis. The use erythropoietin for treatment anemia reduced number blood transfusions, but frequency HCV not declined in hemodialysis units. exact mode transmission within dialysis units is as yet incompletely defined, there evidence to support nosocomial by sharing machines unit. We performed a study estimate prevalence our unit and evaluate effect patient isolation devoted...
Objective: In this study, we compared predialysis and dialysis patients with the controls in terms of insulin resistance evaluated association inflammation that is a risk factor for cardiovascular disease. Materials methods: A total 134 non-diabetic (n = 33), 29) patient group 72) were included study. Fasting blood glucose, insulin, C-peptide, albumin, CRP (C-reactive protein) homocysteine plasma levels simultaneously analyzed all patients. HOMA-IR index was calculated to show existence...
Amyloidosis results from extracellular deposition of a fibrillary protein in various organs, and renal biopsy is the best, but complicated tool for diagnosis. Therefore, alternative sites have been proposed with varying degrees sensitivity. We aimed to find most appropriate site patients chronic kidney disease (CKD) whom contraindicated or unavailable. 42 (29 male; mean age 46 ± 16 y) CKD amyloidosis was suspected as underlying etiology on clinical grounds, not available (Group I), 36 (25 40...
The aims of this study are to evaluate the serum levels paraoxonase (PON) and arylesterase (ARE) in breast cancer (BC) patients; determine their relationship with chemotherapy requirements BC; find a cut-off value assess subjects higher risk BC.A total 40 BC patients 33 age-matched healthy women were included study. Beside other biochemical parameters, participants' PON ARE determined analyzed.Serum found decreased sera (96.44 ± 21 159.75 15.75 U/L, respectively)compared controls (158.39...
<b><i>Background/Aims:</i></b> Cardiac valve calcification (CVC) and left ventricular (LV) abnormalities are common indicators of a poor prognosis in dialysis patients. We determined the prevalence hypertension, CVC, LV hypertrophy (LVH) geometry peritoneal (PD) <b><i>Methods:</i></b> Eighty-seven patients (50 female; mean age 42 ± 13 years; duration 46 24 months) on strict salt volume restriction, none whom were receiving antihypertensives,...
It is known that depression common in obese individuals. Besides the effects of obesity, pathogenic increase visceral and abdominal fat mass on are also being investigated. Our study aimed to show relationship between percentage detected with practical methods presence severity depression.Our included 104 patients 50 healthy controls. In all individuals, was assessed using Beck Depression Inventory (BDI). Anthropometric measurements, percentage, body were measured bioelectric impedance...
Introduction:In this study we aimed to detect paraoxonase 1 (PON-1) activity in iron deficiency anemia (IDA) and compare it with healthy controls by observing the change after therapy.Material methods: In study, 50 adult patients IDA 40 subjects were enrolled.All analyzed at beginning treatment according laboratory assessments.Results: Mean arylesterase activities group significantly lower than mean of control (102.4 ±19.2 U/l 163.3 ±13.68 U/l, respectively 157.3 ±26.4 256.1 ±24.6...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Introduction. In this study, we aimed to demonstrate the correlation of FGF-23 levels with bone-mineral metabolism, anemia, and treatment in dialysis patients. Methods. Eighty-nine patients similar age, gender, duration, adequacy who were receiving hemodialysis replacement therapy for at least 6 months included study. Serum iron, iron binding capacity, ferritin, hemoglobin (Hb), hematocrit (Htc), calcium (Ca), phosphorus (P), intact parathormone (iPTH), studied. addition, active vitamin D...
To determine the prevalence of metabolic syndrome and its risk factors in various ethnic groups Istanbul, Turkey.Study participants were aged ≥ 20 years. Risk factor components for measured presence was determined study participants.The included 254 Greeks, 273 West Thracians, 275 East Turkistanis 304 Armenians. The significantly different between (Greeks, 19.3%; 24.9%; Turkistanis, 15.3%; Armenians, 20.4%), increased with age all groups. Low levels high-density lipoprotein cholesterol...
Objective: Altered paraoxonase (PON) and arylesterase (ARE) activities have been shown in anemic chronic kidney disease (CKD) patients iron deficiency anemia (IDA) patients. Whether accompanying alone is responsible for this diminished PON ARE CKD or an additive factor not well studied. Therefore, we tried to clarify issue here. Methods: A total of 82 subjects that consisted 19 with IDA (group 1), 23 2), 40 age sex matched healthy 3) were enrolled. Carotid intima media thickness (CIMT),...
Purpose. In this study we tried to determine the association between body-mass index (BMI), survival rate, and stage of tumor at time diagnosis in patients with gastric cancer. Methods. A total 270 cancer patients' hospital records were retrospectively evaluated. Patients grouped according their BMI diagnosis. Tumor stages admission compared values. Results. There no differences OS among subgroups (p = 0.230). The percent III was significantly higher nonobese while IV surprisingly obese...
A 78-year-old male patient who had an indwelling urinary catheter because of benign hyperplasia the prostate and been receiving hemodialysis twice a week due to endstage renal disease was admitted our hospital complaining three days purple urine color (Figure 1).His medications included beta blocker, anti-aggregant, erythropoietin, piracetam calcitriol therapies.A analysis performed; results were as follows: pH: 8.0, density: 1012, leukocyte esterase: (++), leukocyte: 11/HPF (high power...