A5038410736- Endometrial and Cervical Cancer Treatments
- Ovarian function and disorders
- Cancer Risks and Factors
- Reproductive Biology and Fertility
- Maternal and fetal healthcare
- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- Pregnancy and preeclampsia studies
- Cardiovascular Issues in Pregnancy
- Ovarian cancer diagnosis and treatment
- Congenital Diaphragmatic Hernia Studies
- Urinary and Genital Oncology Studies
- Neonatal and Maternal Infections
- Infective Endocarditis Diagnosis and Management
- Dermatological and Skeletal Disorders
- Preterm Birth and Chorioamnionitis
- Sexual Differentiation and Disorders
- Urological Disorders and Treatments
- Pregnancy-related medical research
- Sperm and Testicular Function
- Streptococcal Infections and Treatments
- Hemophilia Treatment and Research
- Connective tissue disorders research
- Blood Coagulation and Thrombosis Mechanisms
- Gestational Diabetes Research and Management
Sapporo Medical University
2018-2023
Obihiro National Hospital
2018
Hyperandrogenism is one of the cardinal symptoms in polycystic ovary syndrome and plays a key role pathogenesis syndrome. However, precise effects mechanisms excess androgen during follicular development are still unclear. Here we investigated on mouse follicle vitro. Androgen did not affect growth follicles smaller than 160–180 μm presence follicle-stimulating hormone (FSH). low FSH, supported larger μm, size at which growing acquire FSH-dependency. change mRNA expression various...
Abstract Background Radical tracheletomy (RT) with pelvic lymphadenectomy has become an option for young patients early invasive uterine cervical cancer who desire to maintain their fertility. However, this operative method entails a high risk the following pregnancy due its radicality. Methods We have performed vaginal RT 71 and experienced 28 pregnancies in 21 patients. They were followed up carefully according follow-up methods we reported previously. Their courses prognoses after...
Umbilical cord entanglement is known to be a major cause of fetal hypoxia and correlated with several neonatal complications, but almost all the previous reports were restricted nuchal cord. In this study, we retrospectively examined correlation between multiple part pregnancy outcomes. A total 2156 cases recruited from term deliveries in our hospital 2008 2012. We counted umbilical loop numbers not only for also trunk limb entanglement. classified into three groups: no loop, single loops...
Abstract Aim Radical trachelectomy (RT) with pelvic lymphadenectomy has become an option for young patients early invasive uterine cervical cancer who decide to maintain their fertility. However, this operative method entails a high risk the following pregnancy due its radicality. Therefore, RT pregnant can be challenge both gynecologic oncologists and obstetricians. Methods We have performed vaginal five stage 1B1 according of Dargent et al. The operations were between 16 26 weeks...
Polycystic ovary syndrome (PCOS) is an endocrine disease that common in women their reproductive period. Patients with this suffer from anovulation and hyperandrogenism. Ovulation induction exogenous gonadotropin often causes ovarian hyperstimulation because many small antral follicles pause growth. Treatment insulin sensitizers reportedly effective for both associated PCOS, suppression of excessive follicular growth; however, the underlying mechanism action remains unknown. Although...
Abstract A 37‐year‐old pregnant woman who had undergone three previous cesarean sections was diagnosed as having placenta percreta. We decided to perform hysterectomy with bilateral common iliac artery balloon occlusion (CIABO). The duration of surgery 2 h and min total estimated blood loss 2600 mL. Surgery completed without any surgical complications, but the pulse oximeter waveform left leg became undetectable during surgery. immediately performed angiography after closure laparotomy found...
Abstract Background Letrozole has been reported to be effective in treating anovulation, preventing ovarian hyperstimulation syndrome (OHSS), and retrieving oocytes breast cancer patients. However, the role mechanism of letrozole follicular development remain unclear. Results We treated mouse preantral follicles with various treatments; we found no significant difference follicle survival rates (LET) group compared control group, but average diameter LET tended larger (CTRL vs. 30, p =...
Cervical varix during pregnancy is a rare condition, and standard management for bleeding from has not been established. We performed cross double cervical cerclage effectively stopped bleeding. A 41-year-old female had twin pregnancy. The development of was observed ruptured started at 20 weeks gestation. surgical hemostasis by cerclage. In the first cerclage, we could stop varix. For further restriction blood supply to varix, second in crossed position on deeper side vagina than Then...
Hereditary antithrombin (AT) deficiency increases the risk of venous thromboembolism (VTE) in pregnant woman. We report first case administration recombinant human (rhAT) to a Japanese woman with AT deficiency. A 30-year-old woman, gravida 2 para 0, was referred our hospital because Unfractionated heparin administered from 13 weeks gestation and rhAT labor onset. cesarean section performed patient her baby were healthy, no sequelae. concluded that effective for preventing VTE during...
Ehlers-Danlos syndrome is a rare genetic disorder that presents with variety of pathologies depending on the disease type. Among them, vascular requires extremely careful management as there have been many reports fatal perinatal complications such uterine rupture. Although hypermobile less likely to cause complications, symptoms arthralgia, hip dislocation, and depression may be seen throughout pregnancy. We report here case twin pregnancy in which was first suspected at 19 weeks gestation....
Abstract Purpose Radical trachelectomy (RT) with pelvic lymphadenectomy has become a new treatment option for young patients uterine cervical cancer stages 1A2–1B1 who desire the preservation of their fertility. However, application RT pregnant is still controversial. We comparatively studied both obstetrical and oncological outcomes underwent vaginal during pregnancy those before pregnancy. Methods Both results eight in our institute between 2010 2020 (Group A), ten same period B) were...