A5037363087- Environmental Toxicology and Ecotoxicology
- Marine Bivalve and Aquaculture Studies
- Aquaculture Nutrition and Growth
- Physiological and biochemical adaptations
- Radioactive contamination and transfer
- Aquatic Invertebrate Ecology and Behavior
- Ocean Acidification Effects and Responses
- Advanced Proteomics Techniques and Applications
- Autophagy in Disease and Therapy
- Cellular Mechanics and Interactions
- Biochemical and Molecular Research
- Heavy metals in environment
- Biological Research and Disease Studies
- Advanced Nanomaterials in Catalysis
- Toxic Organic Pollutants Impact
- Fungal and yeast genetics research
Ocean University of China
2019-2024
Qingdao National Laboratory for Marine Science and Technology
2019-2023
Laoshan Laboratory
2023
This present study was conducted to provide evidence and an explanation for the apoptosis that occurs in marine rotifer Brachionus plicatilis when facing 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) stress. Metabolomics analysis showed aminoacyl-tRNA biosynthesis, valine, leucine isoleucine arginine biosynthesis were top three sensitive pathways BDE-47 exposure, which resulted reduction amino acid pool level. Pyrimidine metabolism purine also significantly influenced, pyrimidine content...
The ionic properties of strontium (Sr), a significant artificial radionuclide in the marine environment, were estimated using stable nuclide-substituting experimental system under controlled laboratory conditions. bio-accumulation Sr and its impacts, as well any possible hidden mechanisms, evaluated based on physiological alterations sentinel blue mussel Mytilus edulis. mussels exposed to series stress-inducing concentrations, with highest solubility being 0.2 g/L. No acute lethality was...
The modified clay is the only worldwide-accepted practical method for mitigating algal bloom. Is it ecologically safe? To evidence it, a simulative bloom-occurring system of Karenia mikimotoi was set up, and sentinel organisms rotifer Brachionus plicatilis in sea surface blue mussel Mytilus edulis on benthos were respectively included. organisms' physiological responses determined as indicators to reflect ecological impacts when settled from bottom during mimic bloom-mitigating process....
Thymosin β4 (Tβ4), a 43-amino acid N α -acetylated peptide, has multiple significant biological functions. There are two bottlenecks to its biosynthesis: the difficulties in obtaining -acetylation and expressing small peptides. In this study we found that ssArd1, an archaeal acetylase from Sulfolobus solfataricus can acetylate N-terminal residue Ser of Tβ4. A modified E. coli BL21(DE3) with ssArd1-expressing cassette integrated locus lpxM chromosome by Red recombination was constructed named...
The energetic response of blue mussel Mytilus edulis when coping with tetrabromodiphenyl ether (BDE-47) exposure was evaluated from the perspective alterations in energy supply mode, and possible regulating mechanism discussed based on a 21-day bioassay. results showed that mode changed concentration: 0.1 μg/L BDE-47 decreased activity isocitrate dehydrogenase (IDH), succinate (SDH), malate oxidative phosphorylation, suggesting inhibition tricarboxylic (TCA) acid cycle aerobic respiration....
Japan's initiation of their nuclear-contaminated water discharge plan has shocked the world, and worldwide attention mainly focused on its potential impacts marine ecosystems. A stable nuclide-substituting method was applied in present study to assess effects strontium (88Sr) sentinel blue mussel Mytilus edulis under controlled lab conditions. No acute lethality observed even upon exposure highest solubility 88Sr (0.2 g/L), but injury key physiological processes occurred different sublethal...