- Microbial Inactivation Methods
- Heme Oxygenase-1 and Carbon Monoxide
- Viral-associated cancers and disorders
- Adipose Tissue and Metabolism
- Ocular and Laser Science Research
- Ovarian cancer diagnosis and treatment
- Collagen: Extraction and Characterization
- Skin and Cellular Biology Research
- Biomarkers in Disease Mechanisms
- Burn Injury Management and Outcomes
- Infectious Diseases and Mycology
- Toxin Mechanisms and Immunotoxins
- Lymphoma Diagnosis and Treatment
- Immune Response and Inflammation
- Genital Health and Disease
- Electrical Fault Detection and Protection
- Advancements in Transdermal Drug Delivery
- Cardiomyopathy and Myosin Studies
- Antimicrobial Resistance in Staphylococcus
- Climate Change and Health Impacts
- Cervical Cancer and HPV Research
- Bacillus and Francisella bacterial research
- Dermatology and Skin Diseases
- Vascular Tumors and Angiosarcomas
- Pregnancy and preeclampsia studies
North Denmark Region
2024
Bispebjerg Hospital
1991-2006
University of Copenhagen
1977-2004
Copenhagen University Hospital
1981-2002
Herlev Hospital
2002
Kiel University
1995
Office of Chief Medical Examiner
1991
Hvidovre Hospital
1981-1990
Leo Pharma (Denmark)
1989-1990
University of the Faroe Islands
1990
Four previously healthy Danish homosexual men developed Kaposi9s sarcoma or opportunistic infections with fever of unknown origin and lymphadenopathy. One patient died a Pneumocystis carinii pneumonia. Three patients had defective cell-mediated immunity absent leucocyte interferon production decreased proliferative response to mitogens antigens. T lymphocyte helper subsets natural killer cell activity were reduced. Unstimulated mononuclear cells produced migration inhibitor factor. Two...
Sixteen rabbits were placed in exposure chambers: eight continuously exposed to 180 ppm of carbon monoxide and atmospheric air for 2 weeks. The myocardial ultrastructure all the was examined. In monoxide, local areas partial or total necrosis myofibrils degenerative changes mitochondria found. Extra- intracellular edema, increases number ribosomes lipofuscin granules, reparative fibrotic also occurred. Varying degrees injury noted blood vessels. Capillary but never stenosis, seen some areas....
An intraobserver and interobserver analysis of the reproducibility revised 1988 International Federation Gynecology Obstetrics (FIGO) grading system endometrial cancers was performed in 47 (94 biopsy specimens). In FIGO growth pattern still serves as basic parameter, but nuclear atypia inappropriate for architectural grade, raises grade by 1. Ninety-four slides were graded twice two pathologists. Analysis kappa statistics (corrected agreement chance) showed an acceptable result...
An interobserver analysis of the reproducibility malignancy grade and histological type classified according to World Health Organization criteria was performed in 261 ovarian tumours, stages IIB IV. All available slides per patient including metastatic tumours (16%) were reviewed independently by two pathologists. Overall observed agreement regarding 68%. The chance-corrected expressed kappa coefficient 0.55 (95% confidence interval 0.49-0.61). 41% compared with a 0.19 0.12-0.26). Kappa...
Rabbits were exposed to carbon monoxide at varying concentrations and for lengths of time in order estimate the threshold limit value myocardial damage. Degenerative changes seen rabbits more than 4h CO higher 100 ppm. This high sensitivity myocardium is explained by combination binding myoglobin prevailing low oxygen tension normal myocardium. The study suggests that content tobacco smoke polluted air may be deleterious persons with ischaemic heart disease. A reevaluation recommended...
Biopsies were obtained from heat and electrically exposed pig skin at different times after exposure, in order to describe the morphological sequences injured skin. The work is part of a series studies which it investigated whether methods can be used disclosing electrical torture. Epidermal changes lesions differed those all experiments. Heat typically showed detached epidermis with fibrillar or granular cytoplasm. In older appeared concrete. Electrical an attached small defects, white,...
The breathing and suspended inspiration techniques are often used interchangeably for spine X-ray examinations. However, these not always adequately supported by clinical evidence. This study aimed to determine the two techniques' diagnostic value adverse image outcomes.
We performed 300 consecutive coronary arteriographies with 2 different kinds of catheters: polyurethane catheters and polyethylene catheters. The thromboembolic complication rate for investigations each type is compared to the surface structure as seen scanning electron microscope (SEM). was 21.4% 0.3% inner irregular, while appeared smooth. outer slight These results are other reports on at arteriography. It concluded that types have thrombogenic properties major importance this difference.
BACKGROUND Studies have suggested that the incidence of classic Kaposi's sarcoma (KS) varies considerably within Europe. The epidemiology KS in Denmark was described for period between 1970 and 1992 association with marital status country origin were evaluated. METHODS A descriptive study carried out using data from Danish Cancer Registry all pathology departments. effects immigration evaluated a case–control sex- age-matched controls 50 cases KS. RESULTS total 59 patients KS, 34 men, 25...
A case of atypical varicella zoster in a 33-year-old AIDS patient is reported. The had two attacks herpes within year and was given high-dose acyclovir several times. Thereafter he developed small keratotic pellucid papules on fingers, wrists face, which were found to contain varicella-zoster antigen by the ELISA test. Skin biopsy showed acanthosis lack vesication, as usually seen infections. varicella-like lesions persisted despite repeated doses but cleared temporarily when foscarnet. We...
We report a case of ulcer bed infection in an enlarging venous leg without clinical signs cellulitis the surrounding tissues. Signs were: 1) cocci‐like structures and bacteria‐like rods around vessel walls viable bed, 2) vasculitis‐like inflammation deeply situated vessels tissue, 3) Pseudomonas aeruginosa ‐specific antibodies serum (other than against exotoxin A), 4) extensive epidermolysis normal human skin by wound exudate vitro , 5) P. A (23 ng/ml). In cell assay, was cytotoxic rabbit to...
To map the expression of Ber-EP4 in well-differentiated squamous epithelia, metaplastic epithelia and dysplastic different origins.Squamous epithelium origin was stained using a standard immunohistochemistry method applied to paraffin sections. We found that normal oral cavity, oesophagus, uterine cervix, vagina, anal canal, branchial cysts are Ber-Ep4-negative, as mature metaplasia bronchial mucosa, urinary bladder mucosa cervical mucosa. In contrast, immature or dysplasia endodermal...
With the aim of being able to trace skin sequelae electrical torture, an interdisciplinary group scientists (the "electrical group" Anti-Torture Research, ATR) has performed controlled morphological studies on biopsies from experiments with fully anesthetized pigs. "Vesicular nuclei" in epidermis and a characteristic pattern collagen calcification dermis were found be typical damage. These alterations produced by alternating current as well direct current.
Background: When dealing with tumors of presumed fibroblastic or fibrohistiocytic origin, immunohistochemistry is traditionally done to exclude a tumor non‐fibroblastic non‐fibrohistiocytic nature, because reliable marker cell origin still be introduced. This study investigates whether procollagen 1 useful skin composed cells derived from fibroblasts fibrohistiocytes. Materials and methods: Twenty‐nine different types tumors, including spindle as well some additional epithelial melanocytic...