A5065955885- Cervical Cancer and HPV Research
- Head and Neck Cancer Studies
- Cancer-related molecular mechanisms research
- HER2/EGFR in Cancer Research
- Folate and B Vitamins Research
- Family Support in Illness
- Liver Disease Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Advanced Breast Cancer Therapies
- Cancer Cells and Metastasis
- Colorectal Cancer Treatments and Studies
- Breast Cancer Treatment Studies
- Childhood Cancer Survivors' Quality of Life
- Health and Wellbeing Research
- Cancer Diagnosis and Treatment
- RNA modifications and cancer
- Genetic factors in colorectal cancer
- Ubiquitin and proteasome pathways
- Cancer survivorship and care
- Optimism, Hope, and Well-being
- Acute Myeloid Leukemia Research
Jiangnan University
2023-2025
Wuxi Fourth People's Hospital
2025
Sun Yat-sen Memorial Hospital
2022-2024
Sun Yat-sen University
2022-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
Peking Union Medical College Hospital
2023
Lymphoma patients often experience significant physical and psychological stress, with feelings of powerlessness negatively impacting their health. While social support hope are crucial for improving mood coping disease, mechanisms in relation to disease perception remain unclear. This study aimed examine the relationship between lymphoma patients, focusing on mediating roles hope. For a cross-sectional design, 311 were surveyed using Brief illness questionnaire, Powerlessness assessment...
<h2>Abstract</h2><h3>Objective</h3> This study identified the potential subgroups of fear cancer recurrence (FCR) in family caregivers (FCs) patients with hematologic malignancies receiving chemotherapy, as well exploring factors associated subgroups. <h3>Methods</h3> was a cross-sectional involving 206 pairs participating chemotherapy and their FCs. Using Mplus 8.3 to perform Latent Profile Analysis FCs' FCR. The burden, quality life, psychological resilience anxiety demographic...
Highlights•This trial evaluates the efficacy and safety of pyrotinib combined with chemotherapy•Patients luminal/HER2-low (IHC 2+/FISH-negative) early breast cancers are included•Pyrotinib chemotherapy has promising anti-tumor activity in (pre)clinical study•Pyrotinib a manageable toxicity profileSummaryThe prognosis patients luminal/human epidermal growth factor receptor 2 (HER2)-low cancer (EBC) needs to be improved. This preclinical study phase (ChiCTR2100047233) aims explore (a pan-HER...
Human papillomavirus (HPV) infection is a predominant cause of oropharyngeal squamous cell carcinoma. However, there limited knowledge about the epidemiology oral HPV infections among adults in China.We collected data from prospective cohort that enrolled participants Mainland China. A total 9,867 ages at least 20 years provided swab specimens typical areas China (Hebei and Guangdong provinces) 2021. DNA exfoliated cells was tested using nested PCR sequencing. Prevalence subpopulations...
Abstract Background The association between different phenotypes and genotypes of circulating tumor cells (CTCs) efficacy neoadjuvant chemotherapy (NAC) remains uncertain. This study was conducted to evaluate the relationship FTH1 gene-associated CTCs (F-CTC) with/without epithelial-mesenchymal transition (EMT) markers, or their dynamic changes with NAC in patients non-metastatic breast cancer. Patients Methods enrolled 120 cancer who planned undergo NAC. gene EMT markers were detected...
<p>Figure S1 Design and flow chart of the study. Data in this study were from DLCC study, data resource, population selection, information collected statistical methods demonstrated figure. DLCC: Diverse Life-Course Cohort; HIPV: human papillomavirus.</p>
<p>Figure S1 Design and flow chart of the study. Data in this study were from DLCC study, data resource, population selection, information collected statistical methods demonstrated figure. DLCC: Diverse Life-Course Cohort; HIPV: human papillomavirus.</p>
<div>AbstractBackground:<p>Human papillomavirus (HPV) infection is a predominant cause of oropharyngeal squamous cell carcinoma. However, there limited knowledge about the epidemiology oral HPV infections among adults in China.</p>Methods:<p>We collected data from prospective cohort that enrolled participants Mainland China. A total 9,867 ages at least 20 years provided swab specimens typical areas China (Hebei and Guangdong provinces) 2021. DNA exfoliated cells was...
<div>AbstractBackground:<p>Human papillomavirus (HPV) infection is a predominant cause of oropharyngeal squamous cell carcinoma. However, there limited knowledge about the epidemiology oral HPV infections among adults in China.</p>Methods:<p>We collected data from prospective cohort that enrolled participants Mainland China. A total 9,867 ages at least 20 years provided swab specimens typical areas China (Hebei and Guangdong provinces) 2021. DNA exfoliated cells was...
Abstract We discuss the clinical characteristics and prognostic significance of adult individuals with PTPN11 mutations who have developed acute myeloid leukemia (AML) (none promyelocytic leukemia). Next generation sequencing Sanger were used to detect 51 gene mutations, multiplex-PCR was 41 fusion genes from 232 de novo AML patients retrospectively. About 7.76% harbored 20 alterations identified, all which missense in N-SH2 ( n = 16) PTP 4) domains located exon 3. Patients mut had...
TPS620 Background: As a latent new subtype, HER2-low-expressing breast cancer has attracted increasing attention. However, HER2-low-expressing/HR-positive early or locally advanced (E/LABC) the lowest pathological complete response (pCR) rate among all types of cancer. Pyrotinib, small-molecule HER1/HER2/HER4 tyrosine kinase inhibitor, combined with chemotherapy regimen showed excellent efficacy and safety in treatment patients HER2-positive early, metastatic In-vitro experiment pyrotinib...
e12599 Background: Based on epithelial-mesenchymal transition (EMT) markers, circulating tumor cells (CTCs) can be classified into two main subtypes: epithelial CTCs(E-CTCs) and EMT-CTCs. CTCs with high expression of the FTH1 gene (HEF) may related to poor efficacy neoadjuvant chemotherapy (NAC). The relation between HEF pathological complete response (pCR) after NAC is unclear. Methods: 83 non-metastatic breast cancer patients who completed surgery were enrolled in this study, each patient...