A5020550167- Head and Neck Cancer Studies
- Cancer-related molecular mechanisms research
- Social Media in Health Education
- Cancer Immunotherapy and Biomarkers
- Digital Communication and Language
- International Law and Aviation
- Law and Political Science
- Educational Games and Gamification
- Peptidase Inhibition and Analysis
- Focus Groups and Qualitative Methods
- Digital Innovation in Industries
- Viral-associated cancers and disorders
- Cancer-related gene regulation
- European and International Law Studies
University of Cologne
2023-2025
University Hospital Cologne
2023-2024
Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde
2022-2023
Lungenklinik Köln-Merheim
2023
Background: The incidence of oropharyngeal squamous cell carcinoma (OPSCC) is rapidly increasing in high income countries due to its association with persistent high-risk human papilloma virus (HPV) infection. Recent scientific advances have highlighted the importance tumor microenvironment OPSCC. In this study, including 216 OPSCC patients, we analyze composition four established markers cancer associated fibroblasts (CAFs) context intratumoral CD8 T-cell infiltration. Methods:...
Subgroups with a poorer prognosis exist among patients human papillomavirus positive oropharyngeal squamous cell carcinoma (HPV-positive OPSCC). This study aims to identify histological and genetic differences within HPV-positive OPSCC correlate these findings patient outcomes. The included 102 patients, all tested for high-risk HPV DNA p16INK4a expression. Based on histomorphological classification (HPV Prediction Classification, PC), cases were categorized as either classic (cHPV) or...
Oropharyngeal squamous cell carcinoma (OPSCC) is the only subgroup of head neck cancer that presents with an increased incidence. Gender-specific studies in other entities have revealed differences treatment response and prognosis. However, limited data OPSCC according to gender human papillomavirus (HPV) status exist. Therefore, we aimed investigate sex-specific how these may be distributed relation HPV risk factors.This retrospective, bicentric study included 1629 patients diagnosed...
Zusammenfassung Hintergrund Die HNO-App, eine Smartphone-App zur Fort- und Weiterbildung für HNO-Ärzte HNO-Interessierte, ergänzt bestehende Angebote der ärztlichen Aus- Weiterbildung. Das Prinzip des game-based E-Learning kann in Zeiten von Digitalisierung Pandemie neue Perspektiven eröffnen. Herzstück App ist ein großes HNO-Quiz, welchem App-Nutzer im Duell-Modus gegeneinander antreten. vorliegende Arbeit analysiert die Leistung Quizmodul unter Berücksichtigung Fragenkategorien dem...
Einleitung Das HPV-assoziierte Oropharynxkarzinom gilt mittlerweile als eigenständige Tumorentität. Während sowohl steigende Inzidenzen auch starke regionale Unterschiede vielfach beschrieben wurden, fehlen Untersuchungen zum nationalen Inzidenztrend.
Background The ORL-App, a smartphone app for further education and training ORL doctors those interested in ORL, complements existing offers medical training. principle of game-based e-learning can open up new perspectives times digitalisation pandemic. heart the is large quiz, which users compete against each other. This paper analyses performance quiz module, taking into account questions’ categories users’ level education.
Hintergrund Die HNO-App, eine Smartphone-App zur Fort- und Weiterbildung für HNO-ärzte HNO-Interessierte, ergänzt bestehende Angebote der ärztlichen Aus- Weiterbildung. Das Prinzip des game-based E-Learning kann in Zeiten von Digitalisierung Pandemie neue Perspektiven eröffnen. Herzstück App ist ein großes HNO-Quiz, welchem App-Nutzer im Duell-Modus gegeneinander antreten. vorliegende Arbeit analysiert die Leistung Quizmodul unter Berücksichtigung Fragenkategorien dem Ausbildungsstand Nutzer.
Introduction HPV-associated oropharyngeal carcinoma is considered a distinct tumor entity. While increasing incidences and strong regional differences have been widely described, studies on the national incidence trend are lacking.