A5019360509- Ocular Surface and Contact Lens
- Advanced Drug Delivery Systems
- Anesthesia and Pain Management
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Pain Management and Opioid Use
- Natural Antidiabetic Agents Studies
- Spectroscopy and Chemometric Analyses
- Corneal Surgery and Treatments
- Bee Products Chemical Analysis
- Drug Solubulity and Delivery Systems
- Ocular Infections and Treatments
- Anesthesia and Neurotoxicity Research
- Crystallization and Solubility Studies
De Montfort University
2024-2025
Universidade Federal de Minas Gerais
2022-2025
Background: This study demonstrates the application of sequential design experiments (DoE) approach within quality by (QbD) framework to optimize extrusion processes through screening, optimization, and robustness testing. Methods: An in-line UV–Vis process analytical technology (PAT) system was successfully employed monitor critical attributes (CQAs) piroxicam amorphous solid dispersion (ASD) products, specifically lightness (L*). Results: L* measurement proved highly effective for ensuring...
At present, ophthalmic drug delivery remains a major challenge, given the eye's prot ective structure and susceptibility to irritation, resulting in poor patient adherence. In order overcome these constraints, new formulations are continually being developed. The inclusion of Galactoxyloglucan (Tamarind seed polysaccharide (TSP) such formulations, natural substance extracted from seeds Tamarindus indica, has shown great potential due its physico - chemical properties, high biocompatibility...
In the hospital environment, postoperative pain is a common occurrence that impairs patient recovery and rehabilitation lengthens hospitalization time. Racemic bupivacaine hydrochloride (CBV) Novabupi® (NBV) (S (-) 75% R (+) 25% hydrochloride) are two examples of local anesthetics used in management, latter being an alternative with less deleterious effects. present study, biodegradable implants were developed using Poly(L-lactide-co-glycolide) through hot molding technique, evaluating their...