Marcela Coelho Silva Ribeiro

ORCID: 0000-0002-2943-2515
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About
Contact & Profiles
Research Areas
  • Retinal Development and Disorders
  • Retinal Diseases and Treatments
  • RNA Interference and Gene Delivery
  • Retinal and Macular Surgery
  • Advanced biosensing and bioanalysis techniques
  • Sugarcane Cultivation and Processing
  • Photochromic and Fluorescence Chemistry
  • Glaucoma and retinal disorders
  • Virus-based gene therapy research
  • Ocular Infections and Treatments
  • Business and Management Studies
  • Social Media and Politics
  • Power Transformer Diagnostics and Insulation
  • Neuroscience and Neural Engineering
  • Photoreceptor and optogenetics research
  • MicroRNA in disease regulation
  • Social and Economic Solidarity
  • Cultural, Media, and Literary Studies
  • Machine Fault Diagnosis Techniques

Universidade Federal de Minas Gerais
2018-2025

Unité de Technologies Chimiques et Biologiques pour la Santé
2020-2021

Université Paris Cité
2020-2021

Inserm
2020-2021

Centre National de la Recherche Scientifique
2020-2021

Universidade Federal de Uberlândia
2020

Universidade Federal de Juiz de Fora
2017

Currently, most nonviral nucleic acid vectors are in the form of colloidal suspensions administered primarily parenterally. This type formulation and mode administration impose strong constraints such as size or production sterile preparations. The tablet provides access to easy oral administration, well accepted by patients; As regards vectors, a dry represents an advance terms stability. Using optimized lipid-based small interfering RNA-delivery system, we studied tabletability liquid...

10.1021/acs.molpharmaceut.9b01190 article EN Molecular Pharmaceutics 2020-03-03

Since the possibility of silencing specific genes linked to retinal degeneration has become a reality with use small interfering RNAs (siRNAs), this technology been widely studied promote treatment several ocular diseases. Despite recent advances, clinical success gene in retina is significantly reduced by inherent anatomical and physiological barriers, new strategies are required achieve intraocular therapeutic effectiveness. In study, we developed lipoplexes, prepared sodium alginate as an...

10.3390/pharmaceutics13060845 article EN cc-by Pharmaceutics 2021-06-08

The incorporation of siRNA into nanocarriers is mandatory to facilitate its intracellular delivery, as itself cannot enter cells. However, the these oral, solid dosage forms and their fate in gastrointestinal environment yet be explored. In present work, of, (i) naked siRNA, (ii) freshly prepared lipoplexes, (iii) tableted simulated gastric intestinal fluids was studied. either released from or protected within quantified by gel electrophoresis efficacy assessed cell transfection. lipoplexes...

10.3390/pharmaceutics13111807 article EN cc-by Pharmaceutics 2021-10-28

Eye diseases have a high socioeconomic impact on society and may be one of the fields in which most stem cell-related scientific accomplishments been achieved recently. In this context, human Pluripotent Stem Cell (hPSC) technology arises as an important tool to produce study Embryonic cell derived-Retinal Pigmented Epithelial Cells (hES-RPE) for several applications, such therapy, disease modeling, drug screening. The use pre-clinical phases attends overall population desire animal-free...

10.15283/ijsc20094 article EN International Journal of Stem Cells 2020-12-30

Este artigo apresenta a aplicação da Transformada Rápida de Fourier (Fast Transformer - FFT) na detecção precoce defeitos em máquinas elétricas rotativas. Os sinais corrente e tensão são coletados externamente ao conjunto análise (motor-carga ou gerador-máquina primária) através transdutores especiais desenvolvidos para esta finalidade durante sua operação normal. Estes sinais, inicialmente adquiridos no domínio do tempo, carregam não só dados operativos conjunto, mas também suas...

10.5151/mathpro-cnmai-0111 article PT cc-by 2015-04-01

Este artigo examina apropriações midiáticas pelo feminismo negro baseadas em reflexões teórico-conceituais sobre a problemática da comunicação sociedades midiatizadas e suas relações com literacia midiática. O Instituto Mulher Negra Geledés, fundado 1998 no período redemocratização brasileira, constitui-se objeto de investigação. movimento Geledés foi observado mapeado sua página site rede social Facebook, durante um consecutivo oito semanas 2016, o propósito identificar modalidades...

10.20873/uft.2447-4266.2017v3n1p205 article PT Revista Observatório 2017-03-30

10.14211/xi-egepe-118119 article PT cc-by Anais do XI EGEPE - Encontro de Estudos sobre Empreendedorismo e Gestão de Pequenas Empresas 2020-01-01
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