- Colorectal Cancer Surgical Treatments
- Anorectal Disease Treatments and Outcomes
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 and healthcare impacts
- Colorectal Cancer Treatments and Studies
- Appendicitis Diagnosis and Management
- Diverticular Disease and Complications
- Nutrition and Health in Aging
- Inflammatory Bowel Disease
- Stoma care and complications
- Microscopic Colitis
- Surgical Simulation and Training
- Colorectal Cancer Screening and Detection
- Enhanced Recovery After Surgery
- Trauma and Emergency Care Studies
- Cytokine Signaling Pathways and Interactions
- Pelvic floor disorders treatments
- Pancreatic and Hepatic Oncology Research
- Eosinophilic Esophagitis
- Hip and Femur Fractures
- Genetic factors in colorectal cancer
- Intraperitoneal and Appendiceal Malignancies
- Esophageal and GI Pathology
Clinique Hartmann
2024-2025
Sir Charles Gairdner Hospital
2024
University of Rome Tor Vergata
2020-2024
Carlo Forlanini Hospital
2022
Policlinico Tor Vergata
2021-2022
Colorectal cancer (CRC) cells contain elevated levels of active signal transducer and the activator transcription (Stat)-3, which exerts proliferative anti-apoptotic effects. Various molecules produced in CRC tissue can activate Stat3, but mechanisms that amplify such an activation are yet to be determined. In this paper, we assessed whether Smad7, inhibitor Transforiming Growth Factor (TGF)-β1 activity, sustains Stat3 expression/activation cells. Both Smad7 phosphorylated...
Hemorrhoidal disease represents one of the most common anorectal disorders in general population. Energy devices, such as LigaSureTM scalpel, have reshaped concept hemorrhoid surgery and turn, improved patient outcomes simplified work surgeon.The study aims to evaluate hemorrhoidectomy (LH) analyzing main post-operative complications rate, length stay, operating time, time return work.In this monocentric descriptive study, from June 2001 February 2019, 1454 consecutive patients, treated with...
Abstract Acute diverticulitis (AD) is associated with relevant morbidity/mortality and increasing worldwide, thus becoming a major issue for national health systems. AD may be challenging, as clinical relevance varies widely, ranging from asymptomatic picture to life-threatening conditions, continuously evolving diagnostic tools, classifications, management. A 33-item-questionnaire was administered residents surgeons analyze the actual practice verify real spread of recent recommendations,...
Immunonutrition (IN) appears to reduce infective complications and in-hospital length of stay (LOS) after major gastrointestinal surgery, but its use in normo-nourished patients is still controversial. The primary aim this comparative observational study was evaluate if pre-operative IN reduces undergoing laparoscopic colorectal resection for cancer under an enhanced recovery surgery (ERAS) program. influence on time first bowel movements, full oral diet tolerance, number type complications,...
Abstract Purpose Routine use of abdominal drain or prolonged antibiotic prophylaxis is no longer part current clinical practice in colorectal surgery. Nevertheless, patients undergoing laparoscopic right hemicolectomy with intracorporeal anastomosis (ICA), it may reduce perioperative contamination. Furthermore, cancer patients, surgery extensive dissection such as central vascular ligation and complete mesocolon excision D3 lymphadenectomy (altogether radical colectomy RRC) called...
Low rectal Carcinoma arising at the background of Ulcerative Colitis poses significant management challenges to clinicians. The complex decision-making requires discussion multidisciplinary team meeting. published literature is scarce, and there are variations in such patients. We reviewed treatment protocols operative strategies; with aim providing a practical framework for low cancer complicating UC. A algorithm proposed.
Address: 1Department of General and Specialistic Surgery, Second University Naples, Italy, 2Colorectal Surgical Oncology, National Institute Tumors 3Radiotherapy, 4Radiotherapy, Hospital G. Moscati Avellino, 5Medical 6Pathology, 7Radiology, Italy 8Endoscopy, * Corresponding author