A5058319190- Sarcoma Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Cancer Diagnosis and Treatment
- Bone health and treatments
- Management of metastatic bone disease
- Bone Tumor Diagnosis and Treatments
- Musculoskeletal synovial abnormalities and treatments
- Radiopharmaceutical Chemistry and Applications
- Global Cancer Incidence and Screening
- Radiomics and Machine Learning in Medical Imaging
- Pelvic and Acetabular Injuries
- Oral and Maxillofacial Pathology
- Orthopaedic implants and arthroplasty
- Medical and Biological Sciences
- Metabolism and Genetic Disorders
- Orthopedic Infections and Treatments
- Mitochondrial Function and Pathology
- Medical Imaging and Pathology Studies
- Healthcare Systems and Public Health
- Cancer Genomics and Diagnostics
- Healthcare and Venom Research
- Facial Nerve Paralysis Treatment and Research
- Temporomandibular Joint Disorders
- Prostate Cancer Treatment and Research
- Breast Cancer Treatment Studies
Ministry of Health of the Russian Federation
2019-2022
Russian Cancer Research Center NN Blokhin
2016-2021
Purpose: To determine the diagnostic capabilities of body scan (BS) and SPECT/CT in diagnosis various variants bone metastases (BM). Material methods: The data 37 patients with BM breast cancer (20 patients), prostate (7 patients) other tumors localization (10 were analyzed. study was carried out two stages: first, BS performed, 3 hours after intravenous introduction an osteotropic radiopharmaceutical labeled 99mTc (technephor or phosphotech), followed by selected zone interest. All studies...
Introduction . Primary malignant tumors of the skeletal system mostly develop in young and middle-aged people. Morbidity this age group amounts to between 75 80 % overall morbidity. Due low survival caused by patient death first 5 years because metastases primary tumors, main focus treatment was on prolongation life, study development new methods conservative therapy. Therefore, until early 1970 amputation surgery generally accepted standard surgical intervention. Positive oncological...
Purpose. To evaluate the capabilities of whole-body MRI based on accelerated acquisition sequences in assessing extent malignancy. Material and methods. The study included 30 patients with malignant, solid tumors various origins metastatic lesions anatomical structures. All underwent WB-MRI, data collection sequences, subsequent clarifying studies, such as CT, PET/ ultrasound to confirm or refute malignancy detected changes. Results. In 14 out cases, it was possible identify additional...
Purpose : To demonstrate a clinical case of metastatic lesions the bones, which clearly reflects difference in sensitivity diagnostic methods SPECT/CT and MRI. Material A 69-year-old female patient with poorly differentiated gastric adenocarcinoma, underwent WBS, Results MRI revealed several metastases that were not reflected on examination. Conclusion Despite high specificity SPECT/CT, some cases additional are required. allows to clarify and, possibly, detect previously undetected metastases.
This article reveals a clinical case dedicated to young woman, professional athlete, who made an appointment at NN Blokhin Russian Cancer Research Center for differential diagnostics of left tibia bone lesion, diagnosed by local health facilities. There were no patient complaints during routine check-up. Oncologist scan and second opinion on CT (was also made). Incidental findings scintigraphy required further investigation. So decision perform hybrid SPECT/CT pelvis, MRI pelvis talocrural...
Objective: to improve breast cancer diagnosis using an independent mammographic teleassessment by two radiologists. Material and methods. The results of a dual assessment 3440 X-ray examinations were analyzed. first was made radiologist from therapeutic-and-prophylactic establishment who had less than one year practical experience in mammography screening room. second carried out with more 5 years specialized institution. Results. According the developed interpretation software,...
The use of mammography breast cancer screening in the world allows to reduce mortality from this widespread disease by 15-30% general women population. Currently U.S. and many European countries different standards screening, which principles are same widely applied. examination standardization its interpretation is generally accepted for differentiation entire flow healthy included process into groups that require recommendations monitoring after first round screening. To errors reports...
Chondrosarcoma is one of the most common tumors in adults. Correct grading chondrosarcoma important criterion that defines course surgical treatment. A case report a 56 years old female patient with pelvic bone presented. The assistance magnetic resonance tomography accurate tumor shown.
A 43-year-old man presented with a history of osteogenic sarcoma lower third the right femur bone. In dynamic monitoring (2011–2018) in Nuclear Medicine Department N.N. Blokhin National Medical Research Centre oncology, Moscow, Russia total 48 radionuclide diagnostic studies were performed: 24 bone scans, 19 SPECT/CT (areas interest) and 5 scintigraphies. The results diagnostics allowed to identify 6 episodes progression underlying condition earlier than X-ray methods imaging form appearance...
Relevance : Radionuclide bone scan signs of lesions are not specific and require radiological identification. Hybrid tomographic technology is a combination spatial distribution radiopharmaceuticals its anatomical binding. Thus, makes it possible to accurately identify the affected structure also determine nature this changes (radiological anatomy). In cancer patients, SPECT/CT method allows visualize tumor pathology in bones, but keeps minimum errors other excessive examinations. Purpose To...
At present the oncologists have great potentialities in diagnostic techniques that enable to determine not only structural but functional characteristics of tumor as well. The use modern technologies medical visualization for diagnosis, determination disease stage and effectiveness neoadjuvant chemotherapy patients with bone sarcomas high degree (G3-G4) malignancy is presented.
At present the oncologists have great potentialities in diagnostic techniques that enable to determine not only structural but functional characteristics of tumor as well. The use modern technologies medical visualization for diagnosis, determination disease stage and effectiveness neoadjuvant chemotherapy patients with bone sarcomas high degree (G3-G4) malignancy is presented.
Purpose: Demonstrate the possible manifestations of SAPHO syndrome. Material and methods: 38-year-old woman with suspected syndrome were performed scintigraphy SPECT/CT for evaluate localization abundance process. Results: Osteosclerosis hyperostosis left clavicle, osteosclerosis L1 vertebra other, less pronounced changes, accompanied by active accumulation 99mTc-MDP, revealed. Conclusion: It is important to remember specific complex symptoms this nosological entity isolated onset individual...
Aim: To evaluate the possibilities of absolute and relative values apparent diffusion coefficient (ADC) in diagnosis metastatic lesions skeletal bones. Material methods: The study included 12 patients with bone lesions, before any treatment was applied. age ranged from 38 to 73 years, 3 men, 9 women. Among morphological forms tumors were presented: cancers breast (3), prostate (1) glands, colon (1), lung (2), body cervix uterus, thyroid pancreas (2). detected changes classified on basis Bone...
Purpose: To demonstrate the diagnostic capabilities to control effects of radiotherapy and HIFU treatment in patient with osteosarcoma bone metastases by SPECT/CT method. Material methods . It was conducted monitoring after external radiotherapy, ultrasound ablation cyber knife. Results. were detected changes SPECT/CT-images treated bones short time. The effect induced manifested 1 month observation. has proven as a reliable method dynamic at radiotherapy. all these is reduce or absence...
The study objective : using a clinical example to demonstrate possibilities of single photon emission computerized tomography (SPECT) in combination with computed (CT) identifying latent bone metastases, taking into account the dynamics growth serum basal calcitonin. Materials and methods . Patient S., 60 years old, visited N.N. Blokhin National Medical Research Center Oncology for consultation on multiple lung metastases cancer unknown primary. Results. Taking calcitonin level,...
Purpose: Is to demonstrate functional and structural changes in the musculoskeletal system of patient with ochronosis using bone scan hybrid imaging consisting single-photon emission computed tomography (SPECT) X-ray transmission (CT) (SPECT/CT).
 Material methods: A clinical case report ochronosis, examined SPECT/CT.
 Results: In this article we show a picture mineral metabolism disorder severe degenerative (a genetically determined disease), caused by metabolic disorders...