- Lung Cancer Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Colorectal and Anal Carcinomas
- Cancer Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Lung Cancer Treatments and Mutations
- Radiopharmaceutical Chemistry and Applications
- Brain Metastases and Treatment
- Sarcoma Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Effects of Radiation Exposure
- Management of metastatic bone disease
- Lung Cancer Research Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatic and Hepatic Oncology Research
- Cancer Research and Treatments
- Healthcare and Venom Research
- Head and Neck Cancer Studies
- Colorectal Cancer Surgical Treatments
- Cancer, Hypoxia, and Metabolism
- Histiocytic Disorders and Treatments
- Soft tissue tumor case studies
Moscow Clinical Scientific Center
2020
Ministry of Health of the Russian Federation
2017-2020
Ministry of Health
2020
Russian Cancer Research Center NN Blokhin
2015-2019
Hydrometeorological Research Centre of Russian Federation
2001
Metastases of primary tumors to the brain develop in 20–40 % cancer patients. Historical information about origin and development stereotactic radiosurgery method are shown, including GammaKnife CyberKnife. The new centers world makes more accessible for article examines modern treatment algorithm cerebral metastases place as a high-dose conformal ablative selected metastatic lesions management these It is shown that provides high level local control survival, similar surgical resection....
Guided by physical needs, we deal with the rotationally isotropic Poincar\'e ball, when considering complement of Borromean rings embedded in it. We consistently describe geometry and realize fundamental group as isometry subgroup three dimensions. Applying this realization, reveal normal stochastization multifractal behavior within examined model directed random walks on rooted Cayley tree, whose six-branch graphs are associated dendritic polymers. According to Penner, construct...
Purpose: to estimate the rate of locoregional recurrence and distant metastases, grade chemoradiotherapy toxicity when in combination with local hyperthermia for treating squamous cell anal canal cancer T1-4N0,1-3M0-1. Materials methods. 112 patients were treated between 2011 2015 chemotherapy, radiation therapy based on 3D CRT, intensity-modulated (IMRT) volumetric intensity modulated arc (VMAT), hypothermia. Staging was TNM (7th edition): I - 4 (3.6%) patients, II 39 (34.8%) patients; IIIA...
Modern radiotherapy is performed with sophisticated equipment that requires highly qualified professionals. In the Russian Federation responsibilities of Radiation Therapy Technologists (RTTs) are carried out by medical nurses who receive on-the-job training. The article discusses problems RTT education and training, describes our own teaching experience suggests further development for national system in Russia.
The urgency of the problem treating patients with lung cancer is caused by a steady increase in incidence and mortality rates population. Most NSCLC initially present locally advanced or disseminated disease. Currently, simultaneous chemoradiation therapy (CRT) standard for treatment NSCLC, which appears superior to single chemotherapy radiation therapy, while overall survival (OS) rate remains not high enough. Therefore, search optimal combinations chemotherapeutic drugs (CRT), as well...
Treatment of patients with hepatocellular carcinoma is an urgent problem modern oncology. Despite the possibility using various methods local and systemic exposure their continuous improvement, results treatment in general remain unsatisfactory. Modern radiation therapy can be considered as one significant due to relative efficacy acceptable tolerability. Implementation mode stereotactic radiotherapy a promising direction because applying ablative doses restriction healthy organs tissues...
Introduction: Nowadays the stereotactic radiotherapy (SRT) of clinical stage I-II lung cancer patients is choice treatment modality for functionally inoperable patients. It shows safety and high efficiency in achieving local control. Though there a range unsolved issues connected with prediction frequency complications, an integration new technologies planning process allows widening search predictive factors. Material methods. Since 2014, 39 (17 T1N0M0 patients, 22 T2N0M0 patients) I-IIa...
Low-energy laser radiation has a good anti-inflammatory and stimulating effect on the damaged tissues; therefore, it can be used for prevention treatment of both early late radiation-induced skin injuries in patients receiving radiotherapy. So far, low-energy damage remains poorly understood. This article presents brief overview results obtained latest foreign studies as well own experience therapy with breast cancer after simultaneous reconstructive plastic surgery.
Clinical case of the patient with nasopharyngeal carcinomaafter stereotactic radiosurgical treatment for persistent disease after chemoradiotherapyare presented. The diagnostic data PET/CTwith 18F-Fluoroethyl-Ltyrosine (18F-FET)and MRI intravenous contrastof head and neck were included in analysis. There was analyzeda clinical differential diagnosis changes thetemporal lobe brain radiation therapy carcinoma using PET/CT 18F-FET. Identified high accuracy delayed (tumor or necrosis)...
Material and methods: Since 2014, 33 patients with lung cancer of clinical stage I-IIa (cT1N0M0 - 12 patients, T2N0M0 21 patients) have undergone SRT. Verification tumor process was obtained in 30 patients. A third (n = 10) had a history metachronic primary-multiple tumors 31 peripheral cancer. The used variants SRT fractionation were as followed: 10Gr x 5 fractions 22) 7Gr 8 11) BED 100Gy. Results: With median follow-up months (range 3-37 months), 4 (12 %) within the first year...
Objective: to evaluate the effectiveness of salvage radiotherapy in patients with recurrent prostate cancer after radical prostatectomy. Materials and methods. In period from March 2009 January 2015, 92 biochemical recurrences prostatectomy underwent classic fractionation hypofractionation radiation dose. Results conclusion. Median follow-up duration was 40 months (12–78 months). Overall survival 100 %. Local control One (1), 2, 3-year disease-free whole patient group 96, 91, 86 %; it 98,...
Objective. To evaluate efficacy and safety of FOLFIRINOX regimen as induction therapy in borderline resectable unresectable pancreatic cancer. Materials methods. A prospective study included patients with cancer without distant metastases. Patients received up to 6 courses chemotherapy (oxaliplatin 85 mg/m2 i. v., irinotecan 180 calcium folinate 400 5‑fluorouracil v. bolus 2 46‑hours infusion) repeated every 14 days. underwent surgery when radiologic signs resectability were achieved....
Purpose. Control of pain syndrome in patients with locally advanced and recurrent pancreatic cancer using stereotactic radiation therapy (SBRT).
 Materials methods. Our clinical observations relate to 103 (LAPC)and who received the radiological unit NIITs NMI. NN Blokhin "in periods: 2000-2010. 2010-2015. The first group consisted 77 non-resectable cancer, which (1a subgroup), 30 radiotherapy a classical fractionation regimen 54-60 Gy/5 fraction, 40 (1b subgroup) mode hypofractionation....
The study objective is to determine advisability of radiation therapy in patients with recurrent prostate cancer after radical prostatectomy. Materials and methods. In our research 92 were treated by salvage median follow up 48 months. Results. rates 1, 2 3 years disease-free survival 96, 91 86 %. We received that specific antigen doubling time <6 months >0.5 ng/ml before statistical significance associated biochemical failure. results indicate two main negative factors the prognosis...
The main method of treating rare mesenchymal tumors PEComas is surgical removal the tumor and external-beam radiation therapy has historically been considered ineffective. However, individual cases in foreign literature as well this article authors’ experience form clinical case provided it shows possibility achieving some anti-tumor effect due to use aggressive variants therapy. variations stereotactic radiotherapy with high dose per fraction sum an neoadjuvant definitive treatment looks promising.
For more than 10 years, there have been no significant improvements in treatment outcomes for patients with inoperable locally advanced non-small cell lung cancer. At the moment, standard of this category is concurrent chemoradiation therapy. same time, 5-year overall survival rate varies range 15–25%. This indicator contributes to modernization existing approaches, as well search new ways stage III One promising areas combination therapy immunotherapy. Thus, use Imfinzi (durvalumab,...