A5010441693- Bone Metabolism and Diseases
- Phytochemicals and Medicinal Plants
- Ethnobotanical and Medicinal Plants Studies
- Agricultural Economics and Practices
- Bone health and treatments
- Agricultural pest management studies
- Inflammatory mediators and NSAID effects
- Bone health and osteoporosis research
- Osteoarthritis Treatment and Mechanisms
- Natural product bioactivities and synthesis
- Livestock Management and Performance Improvement
- Complementary and Alternative Medicine Studies
- Pharmacological Effects of Medicinal Plants
- Botanical Research and Chemistry
- Mesenchymal stem cell research
- MicroRNA in disease regulation
- Essential Oils and Antimicrobial Activity
- Agronomic Practices and Intercropping Systems
- Genetic and Environmental Crop Studies
- Curcumin's Biomedical Applications
- Bone and Joint Diseases
- Wildlife-Road Interactions and Conservation
- Oral and Maxillofacial Pathology
- Dermatoglyphics and Human Traits
- Plant-based Medicinal Research
Central Drug Research Institute
2016-2025
Indian Institute of Pulses Research
2025
Emory University
2024
Westchester Medical Center
2024
New York Medical College
2024
Career Institute Of Medical & Dental Sciences and Hospital
2023
Central Council for Research in Ayurvedic Science
2023
Government of India
2023
Sardar Patel Post Graduate Institute of Dental and Medical Sciences
2023
Siddhartha Medical College
2022
Northeast States of India is blessed with a wide range physiographic and ecoclimatic conditions the geographical ‘gateway’ for much India's endemic flora as well fauna. It home 17 crop species that represent 47% diversity available in country. The region receives an annual average rainfall 2000 mm accounting about 10% (42.5 mhm) country's total precipitation 420 mhm. Forest cover 14.2 million ha which 54.16% area higher than national (19.39%). By large, characterized by fragility,...
Banana fruit is widely grown and source of income across the tropics. It known for its nutritional qualities well-recognized medicinal applications. Given that banana pulp peel are...
Th e leaves of Alternanthera sessilis (Linn.) R.Br.ex DC (Family Amaranthaceae) were exhaustively extracted by soxhlet apparatus withdiff erent solvents like, petroleum ether (40-60oC), chloroform, acetone, methanol and distilled water in ascending order the polarity. All fi ve extracts subjected to antimicrobial screening using cup plate turbidimetric methods. chloroform extract among all showed maximum zone inhibition signifi cant MIC values above two methods respectively. Hence was taken...
Anthropogenic activities have driven many wildlife species towards extinction. Among these species, the geographic distributions of are poorly documented, which can limit effectiveness conservation. The critically endangered Chinese pangolin (Manis pentadactyla) is experiencing population decline throughout its range due to land-use changes and illegal trade for food traditional medicine. Using distribution records maximum entropy modeling, we predicted potential across Nepal. Most suitable...
A formulation of quercetin-based solid lipid nanoparticles (QSLNs) was developed to increase the bioavailability quercetin, with an aim evaluate its effects on bone health in comparison free quercetin (Q).
Spinacia oleracea is an important dietary vegetable in India and throughout the world has many beneficial effects. It cultivated globally. However, its effect on osteoarthritis that mainly targets cartilage cells remains unknown. In this study we aimed to evaluate anti-osteoarthritic chondro-protective effects of SOE chemically induced (OA).OA was by intra-patellar injection monosodium iodoacetate (MIA) at knee joint rats. then given orally 250 500 mg.kg- 1 day- doses for 28 days these...
Post-menopausal condition augments the biological aging process, characterized by multiple metabolic disorders in which bone loss is most prevalent outcome and usually coupled with sarcopenia. Coexistence of such associated pathogenesis have much worse health outcomes, compared to individuals osteoporosis only. Pre- post-natal development demands calcium from mother fetus during pregnancy lactation leading a significant maternal skeletal loss. It follows an anabolic phase around weaning...
Introduction The fundamental facets of holistic systems such as Ayurveda need adequate positioning while designing clinical trials to examine the safety and efficacy. challenges concerning quality, safety, dosage forms delivery system, diverse basic concepts complex approaches in study design, diagnostic therapeutic procedures, outcomes efficacy, drug interactions also pose certain limitations research. There is a for system medicine approach validate therapies with integration principles...
The molecular hybridization concept led us to design a series of galloyl conjugates flavanones that have potent osteoblast differentiation ability in vitro and promote bone formation vivo. An array studies, especially gene expression osteogenic markers, evinced compound 5e as the most anabolic agent, found be active at 1 pM, which was then further assessed for its potential From vivo studies on rat calvaria fracture defect model, we inferred 5e, an oral dose 5 mg/(kg day), increased genes...
Obesity and osteoporosis are two prevalent conditions that becoming increasingly common worldwide, primarily due to aging populations, imbalanced energy intake, sedentary lifestyles. Obesity, characterized by excessive fat accumulation, osteoporosis, marked reduced bone density increased fracture risk, often interconnected. High-fat diets (HFDs) can exacerbate both promoting marrow adiposity loss. The effect of WFA on the osteogenesis adipogenesis was studied C3H10T1/2 cell line mesenchymal...
Bacopa monnieri (L), belonging to the Scrophulariaceae family and commonly known as Brahmi, is well in India for its CNS activity but neuropharmacological effect has not yet been explored. In present study, antiepileptic effects of plant were investigated. The ethanolic extract monniera was tested anticonvulsant albino rats, using different convulsive models. leaves produced significant all models studied. study shows a probable mechanism action similar that benzodiazepines (GABA agonist)....
Osteoarthritic conditions in ACLT model rats were attenuated by SOE administration.