A5019433860- Antibiotic Resistance in Bacteria
- Enterobacteriaceae and Cronobacter Research
- Bacterial Identification and Susceptibility Testing
- Mycobacterium research and diagnosis
- Pharmaceutical and Antibiotic Environmental Impacts
- Genomics and Phylogenetic Studies
- Antibiotic Use and Resistance
University of Kelaniya
2019-2021
Colombo North Teaching Hospital
2019-2020
Rapidly progressing antibiotic resistance is a great challenge in therapy. In particular, the infections caused by carbapenem-resistant Enterobacteriaceae (CRE) are exceedingly difficult to treat. Carbapenemase production predominant mechanism of CRE. Early and accurate identification carbapenemase-producing (CP-CRE) extremely important for treatment prevention such infections. present study, four phenotypic carbapenemase detection tests were compared an algorithm was developed rapid...
Extended-spectrum β-lactamase producing Enterobacteriaceae (ESBL-PE) and carbapenem-resistant (CRE) are disseminated worldwide posing a serious public health concern. Although, the presence of ESBL-PE CRE in Sri Lanka has been reported, prevalence is unknown. This study aimed to provide up-to-date epidemiological data on multidrug-resistant characterize molecular determinants carbapenemase-producing (CPE) Lanka.A prospective cross-sectional was conducted at tertiary care hospital between...
Abstract Background Extended spectrum β-lactamase producing Enterobacteriaceae (ESBL-PE) and carbapenamase Enterocacteriaceae (CPE) are widely disseminated globally creating a huge public health threat. Even though incidence of multidrug-resistant is rapidly growing, the epidemiological data regarding occurrence CRE in Sri Lanka scarce. In this study, we determined prevalence ESBP-PE genetic determinants CPE. Methods A total 593 clinically significant was isolated from different clinical...
Background: Global dissemination of carbapenemase-producing carbapenem-resistant Enterobacteriaceae (CP-CRE) is a critical public health issue. Thus, timely detection CP-CRE becoming increasingly important to rationalize empiric antibiotic therapy and guide infection control. Although new technologies are available, the culture based biochemical tests more popular in low/middle income countries due high cost associated with modern methods. This research was carried out objective identify...
Abstract The authors have withdrawn this preprint due to author disagreement.