- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Glaucoma and retinal disorders
- Digital Imaging for Blood Diseases
- Nitric Oxide and Endothelin Effects
- Neonatal and fetal brain pathology
- Optical Imaging and Spectroscopy Techniques
- Ophthalmology and Visual Impairment Studies
- Adipose Tissue and Metabolism
- Neuroinflammation and Neurodegeneration Mechanisms
- Atherosclerosis and Cardiovascular Diseases
- Sarcoidosis and Beryllium Toxicity Research
- Eicosanoids and Hypertension Pharmacology
- Remote-Sensing Image Classification
- Advanced Glycation End Products research
- Photoacoustic and Ultrasonic Imaging
- Occupational and environmental lung diseases
- Medical Imaging and Pathology Studies
- Retinal Development and Disorders
- Brain Tumor Detection and Classification
- Neurogenesis and neuroplasticity mechanisms
- Natural product bioactivities and synthesis
- Computational Drug Discovery Methods
Tianjin Medical University
2013-2023
Third Affiliated Hospital of Southern Medical University
2019-2022
Key Laboratory of Guangdong Province
2022
Weatherford College
2021
Zhejiang Chinese Medical University
2020
Shenyang Ninth People's Hospital
2011
To investigate the expression and significance of mechanistic target rapamycin complex 1(mTORC1) in diabetic retinopathy (DR), to find new targets methods for treatment DR.A DR rat model was prepared by general feeding combined with intraperitoneal injection 10% streptozotocin (60 mg/kg). The rats were randomly divided into a control group (NDM group) diabetes (DM group). Three months later, degrees determined using hematoxylin eosin staining, levels p-S6, VEGF, PEDF proteins detected...
Abstract Background: Although many publications in diabetic retinopathy (DR) have been reported, there is no bibliometric analysis. Purpose: To perform a analysis the field of research, to characterize current international status DR identify most effective factors involved this field, and explore research hotspots research. Methods: Based on Web Science Core Collection (WoSCC), was conducted investigate publication trends related DR. Knowledge maps were constructed by VOSviewer v.1.6.10...
Glaucoma is a chronic and irreversible eye disease leading to blindness, early detection particularly important for its diagnosis treatment. To improve the performance of automatic glaucoma diagnosis, method based on multi-feature multi-classifier proposed. Firstly, an average histogram obtained each channel ophthalmic condition, 6 features are extracted from with count pixels their maximum intensity value. Secondly, optimal combination screened classifier 10-fold cross-validation. Finally,...
Abstract Introduction: Age-related macular degeneration (AMD) is a leading cause of visual impairment and severe vision loss, with the number cases expected to increase because aging population. However, many aspects AMD, including how it works treated, have yet be elucidated. This study aims identify evaluate global trends in AMD research over last twenty years visualize frontiers using bibliometric analysis. Methods: We collected all publications on from 2002 2021, analyzed within them,...
Objective To establish an appropriate diabetic retinopathy (DR) risk assessment model for patients with type 2 diabetes mellitus (T2DM). Methods A retrospective clinical analysis. From January 2016 to December 2017, 753 T2DM in the Third Affiliated Hospital of Southern Medical University were analyzed retrospectively. Digital fundus photography was taken all patients. Fasting plasma glucose (FPG), HbA1c, total bilirubin (TB), blood platelet, cholesterol (TC), triglyceride (TG), high...
Spectral imaging technology can obtain a three-dimensional data cube of the target, which has advantage "unification maps". Analyzing "fingerprint" spectral information space targets is powerful method for target identification. In response to needs material identification and key part identification, this paper proposes new computational with high Light utilization detection. A high-resolution spatial image obtained through combination panchromatic channel calculated channel. Introduce...
Aim: To explore the possible mechanism of action Wu Ling San Plus for treatment diabetic macular edema (DME) through network pharmacology and molecular docking. Methods: DME-related genes were searched in drugbank database, GeneCards Online Mendelian Human Genetic (OMIM) TTD database. The Traditional Chinese Medicine Systems Pharmacology (TCMSP) database was applied to screen potential chemically active substances related target proteins drug pairs. A “drug-disease target” regulatory...