Jie Xu

ORCID: 0000-0002-0999-9661
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About
Contact & Profiles
Research Areas
  • Adipose Tissue and Metabolism
  • Endoplasmic Reticulum Stress and Disease
  • Advanced Sensor and Control Systems
  • Grey System Theory Applications
  • Elevator Systems and Control
  • Robotic Mechanisms and Dynamics
  • Microbial Metabolic Engineering and Bioproduction
  • Magnetic Bearings and Levitation Dynamics
  • Diverse Interdisciplinary Research Innovations
  • Lipid metabolism and biosynthesis
  • Animal Genetics and Reproduction
  • Molecular Sensors and Ion Detection
  • Advanced biosensing and bioanalysis techniques
  • Genetics, Aging, and Longevity in Model Organisms
  • Supramolecular Self-Assembly in Materials
  • Pluripotent Stem Cells Research
  • Simulation and Modeling Applications
  • Renal and related cancers

Chinese Academy of Sciences
1996-2022

Kunming Institute of Zoology
2022

Chongqing University
2010-2021

Center for Excellence in Molecular Cell Science
1996

Lipid droplets (LDs) are intracellular organelles that dynamically regulate lipids and energy homeostasis in the cell. LDs can grow through either local lipid synthesis or LD fusion. However, how involving fusion for growth is largely unknown. Here, we show genetic mutation of acox-3 (acyl-CoA oxidase), maoc-1 (enoyl-CoA hydratase), dhs-28 (3-hydroxylacyl-CoA dehydrogenase), daf-22 (3-ketoacyl-CoA thiolase), all involved peroxisomal β-oxidation pathway Caenorhabditis elegans, led to rapid...

10.1016/j.jbc.2022.102179 article EN cc-by-nc-nd Journal of Biological Chemistry 2022-06-23

Coordinated regulation of stress response pathways is crucial for cellular homeostasis. However, crosstalk between the different and physiological significance this remain poorly understood. In study, using model organism C . elegans , we discovered that suppression transcription factor LET-607/CREBH, a regulator defense proteostatic responses, triggers adaptive induction DAF-16-dependent responses. Suppression LET-607 improves resistance extends lifespan in manner. We identified...

10.1371/journal.pgen.1009573 article EN cc-by PLoS Genetics 2021-05-20

Enantiomeric inorganic helical TiO<sub>2</sub> nanofibers directed the different assembly processes of insulin and subsequent cellular behaviors.

10.1039/c9ra04660g article EN cc-by-nc RSC Advances 2019-01-01
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