A5088066727- Reproductive tract infections research
- COVID-19 Clinical Research Studies
- Syphilis Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- HIV/AIDS Research and Interventions
- Adolescent Sexual and Reproductive Health
- Antibiotic Use and Resistance
- SARS-CoV-2 detection and testing
- Long-Term Effects of COVID-19
- MicroRNA in disease regulation
- COVID-19 and healthcare impacts
- HIV Research and Treatment
- Urinary Tract Infections Management
- HIV/AIDS drug development and treatment
- Virology and Viral Diseases
- Nosocomial Infections in ICU
- Antibiotic Resistance in Bacteria
- Phagocytosis and Immune Regulation
- Vagus Nerve Stimulation Research
- Healthcare Systems and Reforms
- HIV/AIDS Impact and Responses
- Diabetes and associated disorders
- Bladder and Urothelial Cancer Treatments
- COVID-19 diagnosis using AI
- Female Genital Mutilation/Cutting Issues
BLK Super Speciality Hospital
2018-2023
Defence Institute of Physiology and Allied Sciences
2021
Maulana Azad Medical College
2013-2018
University of Delhi
2014-2016
Outbreak of COVID-19 pandemic in December 2019 affected millions people globally. After substantial research, several biomarkers for have been validated however no specific and reliable biomarker the prognosis patients with infection exists. Present study was designed to identify predict severity tool formulating treatment. A small cohort subjects (n = 43) were enrolled categorized four groups; Dead 16), Severe 10) Moderate 7) healthy controls 10). Small RNA sequencing done on Illumina...
Early and accurate diagnosis of human immunodeficiency virus (HIV) infection is essential for timely identification patients needing antiretroviral therapy instituting HIV prevention strategies. The primary methodology testing has shifted from enzyme linked immunosorbent assay (ELISA) to rapid diagnostic tests (RDTs) in recent years, especially resource limited settings. However, the performance RDTs a matter concern. In present study an RDT being used as initial test serial based algorithm...
The coronavirus disease (COVID-19) presents across a spectrum of signs and symptoms shows clinico-epidemiological predilections (elderly, those with comorbidities). Delhi is among the highest burden states in India.To report case detection trends profile patients tested positive at designated COVID-19 hospital Northern India.Using an observational (descriptive design) we analyzed data from electronic medical records hospital. All individuals testing for SARS-CoV-2 RNA using reverse...
The neurotrophic potential of SARS-CoV-2 virus is manifesting as various neurological disorders in the present pandemic. Nervous system involvement can be due to direct action on brain tissue or an indirect through activation immune-mediated mechanisms. This study will discuss detailed systematically evaluated clinical profile and relevant investigations outcome 14 laboratory confirmed positive patients presenting with signs symptoms. were further categorized into confirmed, probable,...
ABSTRACT Background: Serology is considered the mainstay of syphilis diagnosis. The limitations traditional serological methods and advent availability novel immunochromatographic assays have led to widespread application rapid point-of-care procedures as screening tools for syphilis. However, these tests not been extensively evaluated. This study was designed evaluate performance a diagnostic test known SD BIOLINE Syphilis 3.0 (SD Biostandard Diagnostics Private Limited, Gurgaon, Haryana,...
The contribution of India to the global burden HIV/AIDS is significant. A major barrier that country has faced in its battle against this disease inadequate and inaccurate information about it among population. present analysis explores knowledge clients attending a voluntary counselling testing (VCT) facility India. Two hundred VCT were assessed regard using structured predesigned questionnaire. Sixty-three (31.5%) respondents had never heard HIV/AIDS. In comparison males, significantly...
<b>Introduction:</b> Many centers for sexually transmitted infections in India perform only a single screening assay diagnosis of syphilis which may yield biological false positive (BFP) reactions. <b>Aims and Objective:</b> The aim this study was to determine the true picture seroprevalence BFP reactions different patient groups. <b>Materials Methods:</b> A total 57,308 serial serum samples obtained over period 5 years from groups were screened by venereal disease research laboratory (VDRL)...
Antimicrobial resistance [AMR] has emerged as a global and national priority establishing an effective surveillance system for antimicrobial is essential prerequisite generating evidence informed policymaking at both state levels. Twenty-four laboratories were enrolled after assessment in the WHO-IAMM Network Surveillance of Resistance Delhi [WINSAR-D]. The NARS- NET standard operating procedures adopted along with its pathogen lists antibiotic panels. members trained to use WHONET software...
WHO and NACO recommend treatment of STIs/RTIs on the basis syndromic case management (SCM), even without laboratory confirmation, which may lead to over-treatment. Thus, this study was conducted evaluate utility diagnosis for confirmation patients with vaginal discharge diagnosed SCM.234 married women in reproductive age group, as having syndrome were included. Normal saline wet-mount slide preparations made detection motile trichomonads. Gram stained smear prepared scored per classification...
Background: Infection prevention and control (IPC) is the key component to curtail spread of infections combating rising antimicrobial resistance (AMR) amongst bacteria.Objectives: The present study was conducted assess knowledge, attitude practices (KAPs) for IPC nurses.Materials Methods: A cross-sectional, multicentric, hospital-based survey on 328 nurses from January November 2018 using a self-administered questionnaire public private quaternary-, tertiary- secondary-level...
Scrub typhus is a febrile illness caused by Orientia tsutsugamushi and transmitted through the bite of larval forms trombiculid mites [1].The signs symptoms disease are relatively nonspecific in areas like Delhi where outbreaks have not been reported so far, low index suspicion makes diagnosis this infection difficult.Furthermore, there paucity information regarding role scrub as cause fever paediatric population.
Sexually transmitted infections (STIs) plays a major role in the spread of Human immunodeficiency virus (HIV) due to common route transmission. These display an epidemiological synergy with HIV.The aim this study was analyse correlation CD4 T lymphocyte cell count, HIV-1 plasma viral load Reproductive tract infections/Sexually (RTIs/STIs) HIV infected females.The included 60 females. An informed consent taken from all subjects. Relevant specimens (genital specimen and blood) were collected...
Reproductive tract infection (RTIs)/sexually transmitted infections (STIs) are recognized as a major public health problem, particularly due to their relationship with HIV infection. Early detection and treatment of Chlamydia trachomatis (CTI) among HIV-infected HIV-uninfected women may impact heterosexual transmission. A total 120 participants were enrolled: 30 seropositive symptoms RTIs, without seronegative RTIs. One endocervical swab was collected from all CTI detected by real-time PCR...
Background: Revised and redefined biomedical waste management (BMWM) rules 2016 are an area of immediate focus for the health care personnel amidst menace created by improper disposal waste, emergence multi drug resistant superbugs harmful emissions.Methods: The present cross sectional study was conducted in Rajiv Gandhi Super speciality hospital, Tahirpur, upcoming referral hospital east Delhi, India. merged with training sessions 13 phases. A self-administered questionnaire pertaining to...
Introduction: A molecular diagnostic laboratory is the cornerstone of Coronavirus Disease-2019 (COVID-19) disease diagnosis, as patient’s treatment and management protocol depend on results. Therefore, conducting these tests must adhere to quality process increase accuracy validity generated reports. Rajiv Gandhi Super Speciality Hospital established its set-up at beginning pandemic. Hence, this study aims generate data help improve weak points. Aim: To assess system for COVID-19 diagnosis....
Coronavirus disease 2019 (COVID-19) is a novel viral that spread as global pandemic in 2020 by infecting millions of people across the world. Its clinical prognosis dependent on various coagulatory parameters since thrombotic events are frequently associated with infection severity.A total 383 COVID-19 patients enrolled Rajiv Gandhi Super Specialty Hospital, Delhi, India, were included present retrospective study. Patients divided into three categories, severe (n = 141), moderate 138), and...
To study the epidemiological characteristics of pandemic by describing clinical profile COVID-19 patients presenting to a super specialty hospital.This was descriptive using medical records who tested positive for SARS-CoV-2 RNA reverse transcription-polymerase chain reaction between 17th March and 15th January 2021 while maintaining confidentiality. The demographic data all were entered in Microsoft Excel statistical analysis done SPSS 21 software. Regression performed P value < 0.05...
Introduction: Urinary tract infections (UTI) are affecting any part of the urinary and most commonly caused by a multitude bacteria.Most tests used these days to detect UTI based on chemical test strips cultures, both which labor time-intensive.The aim our study is establish parameters that could with high certainty. Material & Methods:The was conducted in Department Pathology Rajiv Gandhi Super Speciality Hospital, Delhi.The samples received between January March 2017 were included...
Antiretroviral Therapy (ART) has changed the outlook of Human Immune-deficiency Virus (HIV)/Acquired Immuno Deficiency Syndrome (AIDS) patients worldwide.To analyse trends in baseline CD4+ T cell counts and ART requirements newly diagnosed HIV seropositive individuals a Tertiary care hospital Northern India.Out 1263 clients identified from January 2012 to June 2014, only those 470 were analysed, who registered at linked centre.The mean count study group was 249.77±216.0cells/mm3 that male...
<b>Introduction:</b> Venereal Diseases Research Laboratory (VDRL) is one of the key tests for diagnosis syphilis; however in HIV-positive individuals, it has been reported to give inappropriate results at times. Thus, this study was conducted determine if VDRL test titers vary with severity immunosuppression as determined by CD4 cell count. <b>Materials and Methods:</b> A total 2630 samples from adults were tested qualitative quantitative reactive, <i>Treponema pallidum</i> hemagglutination...
BackgroundPresent study aimed to identify DNA polymorphisms (variants) which can modulate the risk of COVID-19 infection progression severe condition. TaqMan based SNP genotyping assay was performed for 11 single nucleotide (SNPs) in pro-coagulant and anti-coagulant genes.MethodologyA total 33 patients, including dead, moderately infected individuals were compared 35 healthy controls. Both alleles labelled with two different fluorescent dyes (FAM VIC) during formulation. subjects mixed...