Chi Zhao

ORCID: 0000-0002-1051-8386
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About
Contact & Profiles
Research Areas
  • Fermentation and Sensory Analysis
  • Tea Polyphenols and Effects
  • Food Quality and Safety Studies
  • Probiotics and Fermented Foods
  • Metabolomics and Mass Spectrometry Studies
  • Acupuncture Treatment Research Studies
  • Pain Mechanisms and Treatments
  • Functional Brain Connectivity Studies
  • Blood transfusion and management
  • Sleep and related disorders
  • Music Therapy and Health
  • Microbial Metabolism and Applications
  • Advanced MRI Techniques and Applications
  • Biochemical Analysis and Sensing Techniques
  • Platelet Disorders and Treatments
  • Meat and Animal Product Quality
  • Nutrition, Genetics, and Disease
  • Gut microbiota and health
  • Polyamine Metabolism and Applications
  • Genetic Associations and Epidemiology
  • Musculoskeletal pain and rehabilitation
  • Osteoarthritis Treatment and Mechanisms
  • Mycotoxins in Agriculture and Food
  • Infrared Thermography in Medicine
  • Olfactory and Sensory Function Studies

Sichuan Academy of Agricultural Sciences
2019-2025

Institute of Agro-Products Processing Science and Technology
2022-2025

First Affiliated Hospital of Henan University
2022-2025

Henan University
2022-2025

Jiangsu Vocational Institute of Architectural Technology
2025

South China University of Technology
2022-2024

Sichuan Agricultural University
2022-2024

University of Massachusetts Amherst
2024

Shanghai University of Traditional Chinese Medicine
2020-2022

Montefiore Medical Center
2010-2022

Xiaoqu , one of three traditional jiuqu in China, is a saccharifying and fermenting agent used jiu brewing, with different ingredient compositions preparation techniques various regions. The yield quality are significantly affected by the metabolites microbiota ; however, associated relationship remains poorly understood. This study aimed to analyze this typical from Guizhou province China. non-volatile were detected using gas chromatography time-of-flight mass spectrometry, whereas...

10.3389/fmicb.2020.617030 article EN cc-by Frontiers in Microbiology 2021-02-01

Education rapid developing has led to an increasing scale of buildings in universities, resulting a significant increase energy consumption. How predict and optimize campus building consumption is hot research topic. Based on this, Bayesian theory was used construct optimization model for predicting buildings. Firstly, data mining techniques were analyze data, prediction established. Then, the practical application effect this method evaluated through experimental verification. Finally,...

10.1177/14727978251321733 article EN other-oa Journal of Computational Methods in Sciences and Engineering 2025-03-12

Background: Although previous observational studies suggest a potential association between gut microbiota (GM) and knee osteoarthritis (KOA), the causal relationships remain unclear, particularly concerning role of blood metabolites (BMs) as mediators. Elucidating these interactions is crucial for understanding mechanisms underlying KOA progression may inform development novel therapeutic strategies. Objective: This study aimed to determine relationship GM quantify mediating BMs. Methods:...

10.1089/rej.2024.0079 article EN Rejuvenation Research 2025-04-07

To evaluate the effectiveness of Tuina in relieving pain, negative emotions, and disability patients with knee osteoarthritis (KOA).Single-center, parallel, randomized controlled trial.Shanghai Guanghua Integrated Chinese Western Medicine Hospital, Shanghai, China.Adult KOA who were able to speak self-report symptoms eligible.A total 104 randomly allocated receive 6-week treatment (Tuina group) or celecoxib (celecoxib group). Data on collected at baseline, week 2, 4, 6, follow-up (1 month...

10.1093/pm/pnac127 article EN Pain Medicine 2022-08-23

Doubanjiang, a Chinese traditional fermented red pepper paste, is eaten worldwide for its unique flavor. The objective of this study was to evaluate the aroma quality doubanjiang using solvent-assisted flavor evaporation (SAFE) and headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography-olfactometry (GC-O) extract dilution analysis (AEDA). A total 165 volatile compounds, belonging 13 chemical classes, were identified. Esters hydrocarbons predominant groups. Thirteen...

10.3390/molecules24173107 article EN cc-by Molecules 2019-08-27

Suan zuo rou (SZR), a traditional fermented meat from Guizhou province, China, is loved by local people for its unique flavor and nutritional value. However, the microbial communities related characteristics of SZR different regions are unclear. We studied correlation between physicochemical properties volatile compounds (VFCs) 15 samples three in province. The community structure was determined high-throughput sequencing VFCs were identified headspace-solid phase microextraction combined...

10.3389/fmicb.2021.736525 article EN cc-by Frontiers in Microbiology 2021-10-20

We aimed to evaluate the efficacy of electroacupuncture in relieving acute pain after total knee arthroplasty (TKA) and related mechanism.

10.1002/brb3.2913 article EN cc-by Brain and Behavior 2023-02-07

Doubanjiang (DBJ), a mixed fermented broad bean (Vicia faba L.) and red pepper (Capsicum annuum condiment used worldwide, is known for its high-salt content (∼20g/100g). Industry demands sodium reduction in DBJs. In this study, we investigated the physicochemical properties, microbial community changes, pathogen surveillance DBJ samples with varying salt contents (10g/100g, 15g/100g, 20g/100g 25g/100g). Our findings revealed that these could be categorized into two groups: low-salt...

10.1016/j.lwt.2024.116071 article EN cc-by-nc-nd LWT 2024-04-16

Abstract Introduction Knee osteoarthritis (KOA) is characterized by a degenerative change of knee cartilage and secondary bone hyperplasia, resulting in pain, stiffness, abnormal walking gait. Long‐term chronic pain causes considerable cortical plasticity alternations patients. However, the brain structural functional alterations associated with pathological changes joints end‐stage KOA patients remain unclear. This study aimed to analyze connectivity comprehensively understand main...

10.1002/brb3.2479 article EN Brain and Behavior 2021-12-29

Metabolome analysis of high-salt fermented food can be an analytical challenge, as the salts interfere with sample processing and analysis. In this work, we describe a four-channel chemical isotope labeling (CIL) LC–MS approach for comprehensive metabolome food. The workflow includes metabolite extraction, metabolites using dansyl chloride, dansylhydrazine, or p-dimethylaminophenacyl bromide reagents to enhance separation ionization, LC-UV measurement total concentration dansyl-labeled in...

10.1021/acs.jafc.2c03481 article EN Journal of Agricultural and Food Chemistry 2022-07-05

Abstract Black waxy rice wine fermentation metabolites are closely related to the product's final quality. However, little is known about dynamic metabolite changes during fermentation. Here, we used gas chromatography time‐of‐flight mass spectrometry (GC‐TOF‐MS) metabolomics and multivariate statistical analysis explore relationship between time. A total of 159 were identified entire process. The PCA revealed a clear separation samples after 4 days 2 days, 4–24 clustered together. This...

10.1002/fsn3.1507 article EN Food Science & Nutrition 2020-03-27

Vinegar is used as an acidic condiment and preservative worldwide. In Asia, various black vinegars are made from different combinations of grains, such Sichuan bran vinegar (SBV), Shanxi aged (SAV), Zhenjiang aromatic (ZAV), Fujian Monascus (FMV) in China Ehime Japan (JBV). Understanding the chemical compositions can provide information about nutritional values quality taste. This study investigated metabolome using a combination GC-MS, conventional LC-MS, isotope labeling LC-MS. Different...

10.3390/metabo12050427 article EN cc-by Metabolites 2022-05-10

Phenyllactic acid (PLA), a promising food preservative, is safe and effective against broad spectrum of food-borne pathogens. However, its mechanisms toxigenic fungi are still poorly understood. In this study, we applied physicochemical, morphological, metabolomics, transcriptomics analyses to investigate the activity mechanism PLA inhibition typical food-contaminating mold, Aspergillus flavus. The results showed that effectively inhibited growth A. flavus spores reduced aflatoxin B1 (AFB1)...

10.3390/toxins15060370 article EN cc-by Toxins 2023-06-01

Aflatoxin B1 (AFB1) is a carcinogenic mycotoxin present in many foods, posing serious human health problem. Oriental high-salt fermented foods are highly susceptible to AFB1 contamination due their production process and condition. Therefore, it necessary isolate microbial resources that can remove In the current study, forty-nine salt-tolerant microorganisms with ability were isolated from Doubanjiang, Chinese typical red pepper paste. Among them, Bacillus velezensis AD8 had highest removal...

10.1590/fst.122621 article EN Food Science and Technology 2022-01-01

Endoplasmic reticulum (ER) and inflammatory stress responses contribute to islet dysfunction in type 2 diabetes (T2D). Comprehensive genomic understanding of these human whether T2D-associated genetic variants modulate them is lacking. Here, comparative transcriptome epigenome analyses islets exposed ex vivo stressors revealed 30% expressed genes 14% cis-regulatory elements (CREs) as responsive, modulated largely an ER- or cytokine-specific fashion. T2D overlapped 86 stress-responsive CREs,...

10.1016/j.cmet.2024.09.006 article EN cc-by-nc-nd Cell Metabolism 2024-10-08
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