A5100655975- Robotic Path Planning Algorithms
- Robotics and Sensor-Based Localization
- Cancer-related molecular mechanisms research
- Advanced Breast Cancer Therapies
- Traditional Chinese Medicine Studies
- Melanoma and MAPK Pathways
- Immunotherapy and Immune Responses
- Metallurgy and Material Forming
- Metabolomics and Mass Spectrometry Studies
- HER2/EGFR in Cancer Research
- Cancer Immunotherapy and Biomarkers
- MicroRNA in disease regulation
- Spine and Intervertebral Disc Pathology
- Molecular Biology Techniques and Applications
- Circular RNAs in diseases
- Urban Transport Systems Analysis
- Guidance and Control Systems
- Ferroptosis and cancer prognosis
- Supramolecular Chemistry and Complexes
- Glaucoma and retinal disorders
- Histone Deacetylase Inhibitors Research
- Access Control and Trust
- Identification and Quantification in Food
- Aluminum Alloy Microstructure Properties
- Big Data Technologies and Applications
Jiading District Central Hospital
2019-2025
Zhejiang University of Technology
2022-2024
Tang Hospital
2022-2024
Sun Yat-sen University
2024
Shanghai University of Traditional Chinese Medicine
2024
Shanghai University of Medicine and Health Sciences
2024
Peking University
2019-2023
Zhejiang University
2023
Xijing Hospital
2022-2023
Air Force Medical University
2023
Metformin treatment is associated with vitamin B12 deficiency, which a risk factor for neuropathy. However, few studies have examined the relationship between metformin and diabetic peripheral neuropathy (DPN), available findings are contradictory. We aimed to assess whether DPN in patients type 2 diabetes mellitus (T2DM) Beijing, China.All newly diagnosed T2DM January 2010 September 2012 Medical Claim Data Employees database were included. was defined as any record of prescription. The...
Abstract Background Breast cancer (BC) is a malignant tumor characterized by high incidence rate and the leading cause of cancer-related deaths among women worldwide. This study aims to identify key genes potential prognostic biomarkers using bioinformatics approach. Methods Three microarray datasets, GSE86374, GSE120129, GSE29044, were downloaded from GEO database. GEO2R Venn diagram software employed differentially expressed (DEGs), while DAVID was utilized for functional enrichment...
Age-related macular degeneration (AMD) is characterized by the degenerative senescence in retinal pigment epithelium (RPE) and photoreceptors, which accompanied accumulation of iron ions aging retina. However, current models acute oxidative stress are still insufficient to simulate gradual progression AMD. To address this, we established chronic injury exposing aRPE-19 cells, 661W mouse retina ion overload over time. Investigations at levels cell biology molecular were performed. It was...
Vinegar is used as an acidic condiment and preservative worldwide. In Asia, various black vinegars are made from different combinations of grains, such Sichuan bran vinegar (SBV), Shanxi aged (SAV), Zhenjiang aromatic (ZAV), Fujian Monascus (FMV) in China Ehime Japan (JBV). Understanding the chemical compositions can provide information about nutritional values quality taste. This study investigated metabolome using a combination GC-MS, conventional LC-MS, isotope labeling LC-MS. Different...
Glioblastoma (GBM) is a highly invasive neurological malignancy with poor prognosis. LncRNA-GAS5 (growth arrest-specific transcript 5) tumor suppressor involved in multiple cancers. In this study, we explored the clinical significance, biological function, and underlying mechanisms of GAS5 GBM. We showed that lncRNA-GAS5 expression decreased high-grade glioma tissues cells, which might be associated overexpression lowered cell viability, suppressed GBM migration invasion, impaired stemness...
To explore the relationship between diabetes and intervertebral disc degeneration in mice associated underlying mechanism. Four-week-old male Kunming were used to model using a high-fat diet combined with streptozotocin injection. After 6 months, morphological pathological changes L4-L6 discs detected by magnetic resonance imaging, micro-CT histological staining. Immunostaining of CD31, F4/80 CD16/32 receptors was detect vascular invasion inflammatory infiltration endplates; exact then...
To develop a new 18 high-risk human papillomavirus (HR HPV) detection and genotyping assay, which is important to evaluate the risk degree of HR HPV for causing cancers. All β-globin relative DNA fragments were synthesized cloned plasmid pUC57 obtain their recombinant plasmids. Based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) platform, each genotypes investigated using constructed The assay was tested 356 clinical specimens results compared...
To investigate the preventive effects of Ilex cornuta aqueous extract (ICAE) on high-fat diet (HFD)-induced fatty liver mice and its mechanisms.Twenty-six male KM (Kunming) were divided into 3 groups, including control group (n = 9), fed with normal diet; HFD HFD; ICAE + 8), administered (3 g·kg-1·d-1) at same time for 10 weeks. Body weight, intra-abdominal subcutaneous fat serum triglyceride (TG), total cholesterol (TC), blood glucose determined to evaluate obesity. The average 24 h food...
The present study explored the attentional processing mechanisms of gaze and arrow cues in two different types conflict tasks. In Experiment 1, participants performed a flanker task which were presented as central targets or bilateral distractors. congruency between direction target distractors was manipulated. Results showed that greatly interfered with gaze, while immune to from Using spatial compatibility task, 2 effects exerted on by their relative locations. When its layout screen,...
Prader-Willi syndrome (PWS) is a multisystem genetic imprinting disorder mainly characterized by hyperphagia and childhood obesity. Extensive structural alterations are expected in PWS patients, their influence on brain nuclei should be early profound. To date, few studies have investigated children with PWS, although functional of the cortex been reported widely.
The damage or apoptosis of retinal ganglion cells (RGCs) is one the leading causes various blinding eye diseases, such as glaucoma, diabetic retinopathy, optic neuritis, and ischemic neuropathy. Oxidative stress involved in RGCs death. Baicalin, a flavonoid compound extracted from Scutellaria baicalensis, has beneficial effects, including anti-inflammatory, anti-apoptotic, antioxidant properties. However, effects baicalin on underlying mechanisms require further investigation.
Excessive accumulation of nitrogen is a major cause water eutrophication. Developing an inexpensive and efficient removal technology therefore essential for wastewater purification. The microbial has been widely used its low cost, high efficiency, strong environmental adaptability. Most recently, with the advances in synthetic biotechnology, artificial multicellular systems have sufficiently developed exhibited unique definability controllability. Compared those natural consortia, pathways...
This paper presents the design, modeling, and experimental validation of CapsuleBot, a compact hybrid aerial-ground vehicle designed for long-term covert reconnaissance. CapsuleBot combines manoeuvrability bicopter in air with energy efficiency noise reduction ground vehicles on ground. To accomplish this, structure named actuated-wheel-rotor has been designed, utilizing sole motor both unilateral rotor tilting configuration wheel movement mode. comes equipped two these structures, enabling...
Chemotherapy has improved the survival of hepatocellular carcinoma (HCC) patients, but underlying mechanisms are still not fully understood. MicroRNAs (miRNAs) critical regulators in carcinogenesis and involved response to cancer therapy. However, correlation between miRNAs chemotherapy is well-established, detailed responsive targets remain unclear. Here, we investigated function mechanism miR-210 HCC with cisplatin.This study samples from patients after surgery, including tumor non-tumor...
Background: The O6-methylguanine-DNA methyltransferase gene (MGMT) promoter methylation status can be used to predict the prognosis of patients with various cancers following treatment alkylating agents. Moreover, MGMT often coexists TP53 mutation. However, has not been identified as a biomarker melanoma. Therefore, this study systematically analyzed prognostic role and correlation between mutation in non-Caucasian
Abstract The NiNiO/GR‐TiO 2 magnetic hollow rod composites based on lignocellulose was prepared via electroless Ni and sol‐gel method to effectively solve that the were difficult recycle reuse. Rapid degradation of organic dyes conducted. element distribution, surface morphology, functional groups characterized SEM, TEM, LSCM FT‐IR, respectively. structure by XRD XPS. photocatalytic properties tested TU‐1950 UV spectrophotometer. EDS demonstrated increase S N elements FT‐IR results,...
The college ideological and political education is brought by numerous dazzled, complex, changeable other diversification of social thought.The efficiently correctly respond to these trends not only the primary task course, but also cultivates improves students' ability identify thought, at same times it reform need.In order dealing with we need improve discriminate, politics course should accurately find point thought from multi aspects theoretical analysis ability.At time, carry out...
By minimizing power flow response, a method of moving asymptotes was adopted to optimize the model by adding and deleting corresponding elements changing material setting position in configuration. To improve dynamic performance whole structure under premise slightly increasing mass structure, Rayleigh damping combined action environment characteristics is established, SIMP (Solid Isotropic Material With Penalization) coupling used calculate response plate-reinforced so that vibration more...