Chaoyang Zhang

ORCID: 0000-0001-6816-3840
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About
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Research Areas
  • Pancreatic and Hepatic Oncology Research
  • Radiomics and Machine Learning in Medical Imaging
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Genomics and Rare Diseases
  • Pancreatitis Pathology and Treatment
  • Cancer-related molecular mechanisms research
  • Neuroendocrine Tumor Research Advances
  • RNA modifications and cancer
  • Cancer Genomics and Diagnostics
  • Geotechnical Engineering and Underground Structures
  • Geotechnical Engineering and Soil Mechanics
  • Rock Mechanics and Modeling
  • Lipid metabolism and disorders
  • Geotechnical Engineering and Soil Stabilization
  • Photoacoustic and Ultrasonic Imaging
  • Optical Imaging and Spectroscopy Techniques
  • Landslides and related hazards
  • Ferroptosis and cancer prognosis
  • Cancer Mechanisms and Therapy
  • AI in cancer detection
  • Meat and Animal Product Quality
  • Lung Cancer Diagnosis and Treatment
  • Stroke Rehabilitation and Recovery
  • Phytochemicals and Antioxidant Activities
  • Grouting, Rheology, and Soil Mechanics

Helmholtz Zentrum München
2024-2025

Inner Mongolia University of Technology
2025

Center for Environmental Health
2025

Chinese PLA General Hospital
2022-2024

Chinese People's Liberation Army
2023-2024

Henan University
2024

Central South University
2016-2024

Enshi Tujia and Miao Autonomous Prefecture Academy of Agricultural Sciences
2024

Tianjin Medical University
2024

China Agricultural University
2019-2024

Background: Ultrasound is used to observe the imaging manifestations of COVID-19 in order provide reference for real-time bedside evaluation.Purpose: To explore ultrasonic peripulmonary lesions non-critical COVID-19, so as clinical diagnosis and efficacy evaluation. Materials Methods: The data 20 patients with clinically diagnosed treated Xi'an Chest Hospital during January February 2020 were retrospectively analyzed. Conventional two-dimensional ultrasound color Doppler characteristics...

10.2139/ssrn.3544750 article EN SSRN Electronic Journal 2020-01-01

Abstract Background: Ultrasound is used to observe the imaging manifestations of COVID-19 in order provide reference for real-time bedside evaluation. Purpose: To explore ultrasonic peripulmonary lesions non-critical COVID-19, so as clinical diagnosis and efficacy Materials Methods: The data 20 patients with clinically diagnosed treated Xi'an Chest Hospital during January February 2020 were retrospectively analyzed. Conventional two-dimensional ultrasound color Doppler characteristics...

10.21203/rs.2.24369/v1 preprint EN cc-by Research Square (Research Square) 2020-02-26

Abstract Hepatocellular carcinoma (HCC) is one of the most dominant causes neoplasm-related deaths worldwide. In this study, we identify and characterize HCCL5, a novel cytoplasmic long noncoding RNA (lncRNA), as crucial oncogene in HCC. HCCL5 promoted cell growth, G1–S transition, invasion, metastasis while inhibiting apoptosis HCC cells both vitro vivo. Moreover, was upregulated TGF-β1-induced classical epithelial-to-mesenchymal transition (EMT) models, lncRNA turn accelerated EMT...

10.1158/0008-5472.can-18-0367 article EN Cancer Research 2018-11-27

A novel image-intensified charge-coupled device (ICCD) imaging system has been developed to perform 3D fluorescence tomographic in the frequency-domain using near-infrared contrast agents. The imager is unique since it (i) employs a large tissue-mimicking phantom, which shaped and sized resemble female breast part of extended chest-wall region, (ii) enables rapid data acquisition by gain-modulated ICCD camera. Diffusion model predictions are compared experimental measurements two different...

10.1088/0031-9155/48/12/303 article EN Physics in Medicine and Biology 2003-06-03

There is no information on the commonality and specificity of oral fecal microbiota in patients with gastric cancer (GC) colorectal (CRC).The high-throughput 16S rRNA gene V4 region sequencing was used to perform bioinformatics analysis oral, fecal, tissue GC (76 subjects), CRC (53), healthy controls (HC, 70). Furthermore, we determined microbial characteristics each part, constructed verified three classifiers for CRC, evaluated curves receiver operating characteristic precision-recall...

10.3389/fcimb.2022.830684 article EN cc-by Frontiers in Cellular and Infection Microbiology 2022-05-19

Abstract E xtra c hromosomal ircular DNA ( eccDNA ) elements are circular molecules that derived from but independent of chromosomal DNA. EccDNA is emerging as a rising star because its ubiquitous existence in cancers and crucial role oncogene amplification tumor progression. In the present study, whole-genome sequencing (WGS) data cancer samples were downloaded public repositories. Afterwards, eccDNAs identified WGS via bioinformatic analyses. To leverage database coverage, also collected...

10.1038/s41388-022-02286-x article EN cc-by Oncogene 2022-04-06

Cervical cancer is a common malignant tumour of the female reproductive system that seriously threatens health women.The aims this study were to identify key genes and pathways illuminate new molecular mechanisms underlying cervical cancer.Altogether, 1829 DEGs identified, including 794 significantly down-regulated 1035 up-regulated DEGs.GO analysis suggested mainly enriched in mitotic cell cycle processes, DNA replication, organelle fission, chromosome segregation phase transition,...

10.7150/ijms.34172 article EN cc-by-nc International Journal of Medical Sciences 2019-01-01

The structural design and manufacturing of spacecraft require meticulous attention to lightweight characteristics, rigidity, stability, which are fundamental for the success space missions. As a result, designs must be subjected rigorous analys is, testing, validation ensure reliability safety. However, use Empirical Mode Decomposition (EMD) methods identifying dense modes presents challenges due endpoint effects, can compromise accuracy modal parameter identification. This study evaluates...

10.1049/icp.2024.3525 article EN IET conference proceedings. 2025-01-01

Metabolic processes are crucial in immune regulation, yet the impact of metabolic heterogeneity on immunological functions remains unclear. Integrating metabolomics into immunology allows exploration interactions multilayered features biological system and molecular regulatory mechanism these features. To elucidate such insight lung squamous cell carcinoma (LUSC), we analyzed 106 LUSC tumor tissues. We performed high-resolution matrix-assisted laser desorption/ionization (MALDI) mass...

10.1080/2162402x.2025.2457797 article EN cc-by-nc OncoImmunology 2025-02-09

Autophagy dysfunction is one of the common causes tumor formation and plays an important role in uveal melanoma (UM). However, little known about regulatory mechanisms autophagy UM. Here, we show that PTK6 can promote proliferation, migration, invasion UM cells by inhibiting autophagy. SOCS3 inhibit cells. Overexpression partially rescue PTK6-induced promotion cell invasion. Mechanistically, bind to SOCS3, downregulate expression PTK6. Furthermore, upregulate phosphorylation mTOR Taken...

10.1038/s41419-023-05590-w article EN cc-by Cell Death and Disease 2023-01-23

The use of large language models (LLMs) in medicine can help physicians improve the quality and effectiveness health care by increasing efficiency medical information management, patient care, research, clinical decision-making.

10.1186/s13018-024-04996-2 article EN cc-by-nc-nd Journal of Orthopaedic Surgery and Research 2024-09-18

Identifying modifiable risk factors early on is essential to prevent major depressive disorder (MDD). This study systematically investigated the causal relationship between 19 and MDD. Single-nucleotide polymorphisms (SNPs) associated with potentially were screened via genome-wide association (GWAS) enrolling individuals of European descent. Summary-level data for MDD (59,851 cases 113,154 controls) extracted from UK Biobank. The inverse-variance-weighted (IVW) method was utilized as primary...

10.1371/journal.pone.0289419 article EN cc-by PLoS ONE 2023-08-03
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