Burn wounds are severely stressful events that can have a significant impact on the mental health of patients. However, burns individuals with different personality traits be different. The present study aimed to investigate dispositional optimism subjective well-being burn patients, and mainly focused confirmation mediator role psychological resilience. 410 patients from five general hospitals in Xi'an accomplished revised Life Orientation Test, Connor-Davidson Resilience Scale, Subjective...

Optimization of skin prick test (SPT) panels, especially in view significant differences sensitizations patterns within different geographical areas, is an unmet need China. Our aim was to assess the and clinical relevance aeroallergen allergic rhinitis (AR) define minimal battery SPT allergens, classified according Köppen-Geiger climate map. Overall, 7148 subjects with self-reported AR completed a standard questionnaire were assessed for sensitization relevant allergens by SPT. 6340 (88.7%)...

Purposes Domestic and international research has found that patients with advanced cancer prioritize increasing their quality of life above extending lives simple or intensive treatments. The current study investigates the pathways to improve patients’ sense well-being from family, social, individual levels, is say, it mediating roles comprehending social support as well psychological resilience in relationship between family subjective well-being, also provides references for future...

Evaluating the clinical value of modified single-incision posterior median approach with expandable tubular assistance for lumbar interbody fusion in managing degenerative spine diseases. A retrospective analysis was conducted on 121 patients single-level disease treated our surgery department from January 2017 to December 2021. Of these, 72 underwent a (single-incision MIS-TLIF group), while 49 received classic open incision P-TLIF (open group). We collected basic demographic data including...

ABSTRACT Objective To clarify the protective effects of gonadotropin‐releasing hormone analogues (GnRHas) on cyclophosphamide (CTX)‐induced oocyte number loss and development potential damage. Design Mice model study. Setting Laboratory‐based animal study conducted in controlled research facilities. Population Female C57/BL6 mice subjected to CTX‐induced ovarian Methods The GnRHa CTX were evaluated terms hormones, count slices, established three‐dimensional–constructed ovaries, vitro...

This study aimed to estimate the prevalence of diabetes mellitus (DM) and impaired fasting glucose (IFG) in a Kazakh population aged ≥18 years living YiLi District Xinjiang, China evaluate associated risk factors diabetes.Randomly selected adults, for at least 6 months Xinjiang had their clinical characteristics standard blood chemistries measured. DM IFG were defined according WHO 1999 criteria. The adjusted odds ratio (ORs) 95% confidence intervals calculated association multivariate...

The aim of the present study was to compare prevalence self-reported and confirmable allergic rhinitis (AR) with positive skin prick test (SPT) results among adults living in urban rural areas China. Adults from a community Beijing village Baoding were selected as representative dwellers, respectively. All eligible residents enrolled population register received face-to-face interview using modified validated questionnaires. Equal sets randomly self-reporting AR-positive AR-negative...

Epstain-Barr virus (EBV) can transform human B lymphocytes making them immortalized and inducing tumorigenic ability in vitro, but the molecular mechanisms remain unclear. The aim of present study is to detect analyze differentially expressed genes two types host cells, normal coupled EBV-transformed lymphoblasts vitro using gene chips, screen key regulatory lymphocyte transformation induced by EB virus.Fresh peripheral blood samples from seven healthy donors were collected. EBV was used...

Many studies have determined the existence of an extremely close association between Internet addiction and depression. However, reasons for depression addicts not been fully investigated. This cross-sectional study aims to explore factors that influence among addicts. A total 162 male completed Emotional Social Loneliness Scale, Multidimensional Scale Perceived Support, Self-Rating Depression Scale. lack social support are significantly correlated with Structural Equation Modeling results...

Background Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and CRS without (CRSsNP) is a global health concern. Several clinical biomarkers, such as inhaled carbon monoxide exhaled nitric oxide (NO), have been studied to assess the presence degree of inflammation in airway mucosa. Objective To evaluate application NO (nNO) distinguishing between CRSwNP CRSsNP consideration atopic status patients. Methods Eighty-eight patients 20 healthy volunteers were recruited for this study. The...

Abstract The coexistence of electrical and chemical synapses among interneurons is essential for interneuron function in the neocortex. However, it remains largely unclear whether coupling between influences synapse formation microcircuit assembly during development. Here, we show that GABAergic connections robustly develop neocortical layer 1 over a similar time course. Electrical promotes action potential generation synchronous firing interneurons. Furthermore, electrically coupled exhibit...

Burn wounds have a significant impact on the mental health of patients. This study aimed to investigate perceived social support and dispositional optimism depression burn A total 246 patients accomplished Multidimensional Scale Perceived Social Support, Revised Life Orientation Test, Depression Scale. The results revealed that both were significantly correlated with depression. Structural equation modeling indicated partially mediated relationship between Implications for prevention in discussed.

Conclusions. The agger nasi cell, together with the postosuperior portion of uncinate process, was key that unlocked frontal recess. Objectives. To investigate anatomical interaction between upper process and cell. Materials methods. Twenty-one skeletal skulls (42 sides) were studied by spiral computed tomography (CT) endoscopy, one cadaver head (2 collodion-embedded sectioning in coronal plane. Results. endoscopic view entrance middle meatus showed part turbinate fused as axilla meatus....

To investigate the relationship between worry tendency and sleep quality mediating effect of state–trait anxiety, 1072 adolescents young adults from Jiangxi Fujian Provinces in China were administered questionnaires pertaining to tendency, quality, anxiety. The results showed significant grade differences for Worry was negatively associated with which mediated by state anxiety trait There is a need interventions that aim reduce level ensure good progression poor quality.

Background Patients are often confronted with diverse medical decisions. Often lacking relevant knowledge, patients fail to independently make decisions and instead generally rely on the advice of doctors. Objective This study investigated characteristics differences in doctor–patient decision making basis construal level theory. Methods A total 420 undergraduates majoring clinical medicine were randomly assigned six groups. Their opt for radiotherapy surgery investigated, choices described...

Background The role of nasal nitric oxide (NO) in the diagnosis allergic rhinitis (AR) is controversial. aim this study was to identify factors that may affect levels NO AR patients and evaluate AR. Methods Seventy‐five 31 healthy controls were enrolled study. symptom scores assessed using visual analog scale. Eosinophil cationic protein (ECP) detected by enzyme‐linked immunoassay, measured a chemiluminescence analyzer, airway resistance (NAR) active anterior rhinomanometry. Results Nasal...

Abstract Background Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized platform used to detect alternative on genome-wide scale. Two probe summarization algorithms, PLIER (Probe Logarithmic Intensity Error) RMA (Robust Multichip Average), commonly compute gene-level exon-level expression values. However, systematic comparison of these two algorithms their effects high-level...

Highlights•A dataset of coffee odor molecules was established•A molecular predictor developed using deep learning•The PredCoffee website built•A systematic computational analysis moleculesSummaryCompared to traditional methods, machine learning assess or predict the can save costs in various aspects. Our research aims collect with and summarize regularity these molecules, ultimately creating a binary classifier that determine whether molecule has odor. In this study, total 371 coffee-odor...

Abstract Background To explore and compare the values of 3.0T magnetic resonance imaging (MRI) T2 mapping in evaluating degree acetabular cartilage degeneration hip replacement surgery. Methods A total 26 elderly patients with femoral neck fractures who were scanned MRI quantification technique included. Basing on images, was classified into Grade 0, 1, 2, 3 4, according to International Cartilage Repair Society (ICRS) scores. In addition, 8 healthy volunteers included for control group....

To develop and validate a predictive nomogram for early stress urinary incontinence (SUI) after endoscopic enucleation of the prostate (EEP) in patients with benign prostatic hyperplasia (BPH).The records 458 who underwent plasmakinetic- or diode-based EEP at our center from March 2016 to December 2019 were reviewed. Among these, 326 132 cases randomly assigned training validation set, respectively. A was constructed based on multivariate logistic regression analysis. Receiver operating...

As a common human pathogen, parvovirus B19 (B19V) has been shown to be associated with many heart diseases, such as myocarditis, cardiomyopathy and cardiopericarditis. The virus protein 1-unique region (VP1u) is critical B19V infectivity, but its role in the pathogenesis of B19V-induced myocardial injury not well studied. In this study investigate effects ofVP1u on host myocardium, we first expressed recombinant VP1u Escherichia coli, produced it large scale by high-volume fermentation,...