A5102854981- Peroxisome Proliferator-Activated Receptors
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cancer, Lipids, and Metabolism
- Lipid metabolism and disorders
- Nutrition, Genetics, and Disease
- Lipoproteins and Cardiovascular Health
- Cholesterol and Lipid Metabolism
- Diabetes Management and Research
- Liver Disease Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Cardiovascular Health and Risk Factors
- Diabetes Treatment and Management
- Obesity and Health Practices
- Blood Pressure and Hypertension Studies
- Selenium in Biological Systems
- Nanoparticles: synthesis and applications
- Retinoids in leukemia and cellular processes
- TGF-β signaling in diseases
- Clusterin in disease pathology
- Folate and B Vitamins Research
- Antioxidant Activity and Oxidative Stress
- Diet, Metabolism, and Disease
- Fluoride Effects and Removal
- Genetic Associations and Epidemiology
- Immune Cell Function and Interaction
Shihezi University
2009-2020
Linyi People's Hospital
2019-2020
Zhengzhou People's Hospital
2015
Arsenic produces liver disease through the oxidative stress. While lutein can alleviate cytotoxic and injury, nuclear factor erythroid 2-related 2 (Nrf2) pathway plays a critical role in defending species. However, mechanisms by which protects against effect of arsenic are not known. Therefore, this study aims to investigate involved action using mice model hepatotoxicity was induced arsenic. We found that treatment with could reverse changes morphological indexes result significant...
This study aimed to estimate the prevalence of diabetes mellitus (DM) and impaired fasting glucose (IFG) in a Kazakh population aged ≥18 years living YiLi District Xinjiang, China evaluate associated risk factors diabetes.Randomly selected adults, for at least 6 months Xinjiang had their clinical characteristics standard blood chemistries measured. DM IFG were defined according WHO 1999 criteria. The adjusted odds ratio (ORs) 95% confidence intervals calculated association multivariate...
Background The global pandemic of obesity has become a disastrous public health issue that needs urgent attention. Previous studies have concentrated in high-income urban settings and few cover low-income rural especially nomadic residents mountain areas. This study focused on minority people residing China's far west investigated their prevalence ethnic differences obesity. Methods A questionnaire-based survey physical examination 8,036 individuals were conducted during 2009–2010, using...
Objective . To study the relationships between IR and glucose lipid metabolism in far western China these relationships’ ethnic heterogeneity. Methods From baseline survey, 419 Uygur cases, 331 Kazak 220 Han cases were randomly selected, resulting a total of 970 for study. FINS concentration was measured by radioimmunoassay. Results (1) In population, correlated with hyperglycemia; high levels TC, TG, LDL-C; low HDL-C abdominal obesity (all <mml:math...
Anatase TiO 2 nanoparticles (NPs) are widely used in food products, capsules, toothpaste, and so on, the kinds of NPs directly get touch with human bodies.The potential effect this kind material on reproduction must be considered increase infertility.Sixty ICR male mice were intragastrically treated dosages 0, 10, 50, 100 mg kg -1 body weight (BW) anatase to investigate reproductive toxicity NPs.Sperm quality, morphological changes testes, oxidative damage indexes investigated study.Results...
We aimed to investigate whether free fatty acid (FFA) levels in hypertensive patients result from increased blood pressure or the accompanying condition of insulin resistance (IR). Furthermore, we study role IR onset and development hypertension then provide a basis for prevention treatment metabolic syndrome (MS).The included 68 essential without IR, 87 normotensive subjects with 82 74 IR. Analysis covariance was used compare FFA concentrations among four groups determine association...
Abstract Chronic kidney disease (CKD) is a persistent structural and functional disorder. Quercetin one of active extracted flavonoids has protective effects. Therefore, we proposed to survey the effect on CKD. HK‐2 cells were preprocessed by then irritated with lipopolysaccharide (LPS). CCK‐8 assay flow cytometry utilized test viability apoptosis. ELISA was estimate IL‐6 TNF‐α secretion. Western blot performed examine expression apoptosis inflammation‐associated mediators. After that...
The present study aimed to estimate prevalence of hypertension among adults in rural remote areas Xinjiang, China and evaluate the associated factors hypertension.The survey was based on questionnaire interviews clinical measurements 11,340 individuals (≥18 years old), conducted during 2009-2010 via a stratified cluster random sampling method about 4407 km away from capital Beijing. Hypertension defined according WHO/ISH criteria.Systolic blood pressure (SBP) diastolic (DBP) population were...
This study aimed to detect the association between polymorphisms and haplotype in ATP-binding cassette transporter A1 (ABCA1) gene overweight/obese Uyghur patients China.A total of 259 276 normal weight subjects, which were randomly selected from among 3049 adult Uyghurs, matched for age. We genotyped ABCA1 single nucleotide rs2515602, rs3890182, rs2275542, rs2230806, rs1800976, rs4149313.(1) The genotypic allelic frequencies rs2515602 rs4149313 differed control group case group. frequency...
We have investigated the relationship between polymorphisms and haplotypes in CETP gene, dyslipidemia among Xinjiang Kazak Uyghur populations China. A total of 712 patients with 764 control subjects gene polymorphism at rs12149545, rs3764261, rs1800775, rs711752, rs708272, rs289714, rs5882, rs1801706 loci were studied by Snapshot method, linkage disequilibrium analysis haplotype construction. The results are as follows: (1) minor allele eight frequencies two groups different from other...
Gene-gene and gene-environment interactions may be partially responsible for dyslipidemia, but studies investigating in the reverse cholesterol transport system (RCT) are limited. We explored these a Xinjiang rural population by genotyping five SNPs using SNPShot technique APOA1, ABCA1, LCAT, which involved RCT (690 patients, 743 controls). conducted unconditional logistical regression analysis to evaluate associations generalized multifactor dimensionality reduction interactions. Results...
To detect the interactions between six functional polymorphisms in ABCA1 and obesity Kazakhs with low HDL-C levels.
Aims. Based on a case–control study, we investigated the relationship between +869T/C and +915G/C gene polymorphisms in transforming growth factor-β1 (TGF-β1), protein levels essential hypertension (EH) Kazakh Han Chinese populations selected from Boertonggu countryside of Shawan region Xinjiang Uygur Autonomous Region China (n=1600). The TGF-β1 blood were detected using polymerase chain reaction–restriction fragment length polymorphism assays sandwich ELISA, respectively. Major findings. An...
This study investigated the prevalence and distribution of dyslipidemia in adults Uygur, Kazak, Han ethnicity Xinjiang, China.A questionnaire including general data, physical examination (blood pressure, body height, weight) blood lipid [total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL-C), high-density (HDL-C)] was administered to 11,506 China from 2009 2010 using a stratified sampling method.The overall rates were 42.4,31.6, 30.2%, respectively; they 42.4,31.8, 28.2%...