Aslıhan Şaylan

ORCID: 0000-0002-1065-3254
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About
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Research Areas
  • Sperm and Testicular Function
  • Reproductive Biology and Fertility
  • Nicotinic Acetylcholine Receptors Study
  • Chemotherapy-induced organ toxicity mitigation
  • Genomics, phytochemicals, and oxidative stress
  • Cholinesterase and Neurodegenerative Diseases
  • Neuroscience and Neuropharmacology Research
  • Medicinal Plants and Neuroprotection
  • Neuroscience of respiration and sleep
  • Bee Products Chemical Analysis
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Pharmacological Effects and Toxicity Studies
  • Natural Antidiabetic Agents Studies
  • Advancements in Transdermal Drug Delivery
  • Epilepsy research and treatment
  • Ovarian function and disorders
  • Neonatal and fetal brain pathology
  • Drug Transport and Resistance Mechanisms
  • Freezing and Crystallization Processes
  • COVID-19 and Mental Health
  • Wound Healing and Treatments
  • Antioxidant Activity and Oxidative Stress
  • Reproductive biology and impacts on aquatic species
  • Alzheimer's disease research and treatments
  • Neonatal Respiratory Health Research

Bolu Abant İzzet Baysal University
2018-2024

Necmettin Erbakan University
2016

Due to the complex nature of Alzheimer's disease (AD), it is important investigate agents with multiple effects in treatment AD. Carvacrol possesses anti-acetylcholinesterase, anti-oxidant, and neuroprotective properties. We therefore investigated therapeutic carvacrol on cell viability, oxidative stress, cognitive impairment Aβ1-42-induced vitro vivo models SH-SY5Y cells differentiated into neurons by retinoic acid were pretreated or galantamine before Aβ1-42 administration. For...

10.1111/ejn.15565 article EN European Journal of Neuroscience 2021-12-14

In 2014, enrolled 20 patients who applied to the Unit of Assisted Reproduction Techniques, Konya Necmettin Erbakan University. Based on presence hyaluronic acid (HA) in oocyte-cumulus cell complex, sperm attached HA vivo were modeled vitro. Available healthy obtained swim-up procedure using investigated.This observational cohort study, a routine analysis was conducted ejaculation samples from patients. We divided each sample into two groups and method applied. Human serum albumin (HSA, 0.5%)...

10.22074/cellj.2016.3990 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2016-01-01

10.1016/j.androl.2022.04.001 article EN Revista Internacional de Andrología 2023-01-05

The aim of the study was to examine protective efficacy astaxanthin (ASTA) against damage that occurs during sperm cryopreservation.This experimental carried out on waste semen samples 30 normozoospermic individuals who applied for analysis. Semen were divided into four equal volumes and 0 μM (control group), 50 μM, 100 500 ASTA added each group. All groups stored frozen in a liquid nitrogen tank. removed from after 72 hours thawed. Motility evaluation performed. In addition, stained with...

10.5489/cuaj.7876 article EN Canadian Urological Association Journal 2022-06-09

Amaç: Tüm dünyayı etkisi altına alan koronavirüs salgını sebebiyle aniden geçilen uzaktan eğitim sisteminin sağlık alanında eğitim öğrenciler tarafından değerlendirilmesi amaçlanmıştır. 
 Gereç ve Yöntemler: Uygulamalı eğitimin önemli bir yer tuttuğu Bolu Abant İzzet Baysal Üniversitesi Diş Hekimliği Fakültesi, Sağlık Bilimleri Tıp Fakültesi Sağlık Meslek Yüksekokulu’nda öğrenim gören 505 öğrenci cevaplandırılan 43 soruluk anket çalışması faktör analizi ile...

10.33631/sabd.1070696 article TR Sağlık Bilimlerinde Değer 2023-01-18

Aim: Aronia melanocarpa is a red-purple medicinal fruit known for its therapeutic properties in the urinary system by anti-inflammatory effects with high antioxidant content. The aim of study to show supportive effect extract delayed toxicity on bladder induced cyclophosphamide (CYC) that an antineoplastic agent. Material and Methods: In three groups were constituted control (n=7), CYC(urotoxicity group, n=7) CYC+ARONIA(treatment n=7). 100 mg/kg CYC intraperitoneally given CYC+ARONIA waited...

10.33631/sabd.1404408 article EN Sağlık Bilimlerinde Değer 2024-10-17

Our aim is to show the supportive effect of Aronia melanocarpa(A. melanocarpa) extract on bladder damage caused by cyclophosphamide(CYC) in delayed period. For this purpose,the was evaluated gas chromatography.Oral gavage(every other day) A.melanocarpa started one month after Wistar rats were given 100mg/kg CYC.After oral gavage repeated 15 times,sacrification performed and tissue examined histologically.P38 MAP Kinase,an inflammatory marker,total antioxidant(TAS) oxidant(TOS) status serums...

10.22541/au.166981378.86541760/v1 preprint EN Authorea (Authorea) 2022-11-30

Background: The aim was to investigate the antioxidant effects of lycopene and caffeine in rats exposed renal ischemia/reperfusion injury. Materials Methods: Following right nephrectomy, 60 minutes ischemia followed by reperfusion were performed 200-250 gram Wistar albino used study. 30 before ischemia, (5 mg/kg), (50 mg/kg) + administered intraperitoneally rats. After experiment, 4 ml blood left kidney taken from Tissue malondialdehyde, glutathione peroxidase, superoxide dismutase serum...

10.35440/hutfd.865165 article EN Harran Üniversitesi Tıp Fakültesi Dergisi 2021-12-20

Abstract The excitotoxicity is a common pathological mechanism of perinatal brain injuries (PBI), however neuroinflammation resulting in PBI both cause and consequence excitotoxicity. TRESK background potassium channels are an important regulator neuronal excitability. We therefore investigated effects activation by selective activator cloxyquin on excitotoxic-induced injury involving mast cells inflammatory cytokines neonatal rats. An excitotoxic model mimicking human lesions was...

10.21203/rs.3.rs-1188598/v1 preprint EN cc-by Research Square (Research Square) 2021-12-28
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