Neuregulin-4 (Nrg-4) is a new adipokine released from brown adipose tissue. It plays pivotal role in regulating systemic energy balance, glucose and lipid metabolism reducing chronic inflammation. We aimed to investigate the relation between diabetic microvascular complications (DMC) serum levels patients with type 2 diabetes mellitus.Patients mellitus were divided into DMC without (non-DMC). Nrg-4 of compared.Fifty 29 enrolled non-DMC groups, respectively. was 1.23 (0.02-5.1) ng/mL 2.5...

Neuregulin-4 is a cytokine with many functions and primarily produced by fat tissue.The aim of the study was to observe relationship between serum neuregulin-4 levels diabetes regulation in type 2 mellitus (T2DM), compare diabetic subjects those healthy controls.Patients T2DM were included study. Healthy enrolled as controls. Subjects glycated haemoglobin (HbA1c) <7% classed well controlled HbA1c >7% poorly controlled. control groups compared.The T2DM, well-controlled significantly different...

To investigate the level of ascorbic acid in human tear fluid after photorefractive keratectomy (PRK), transepithelial PRK, and laser situ keratomileusis (LASIK).Departments Ophthalmology Biochemistry, School Medicine, Gazi University, Ankara, Turkey.Twenty patients (7 women 13 men) were included this study. Traditional PRK with epithelial scraping by a blunt spatula followed surface ablation eyes), or LASIK (6 eyes) was performed. Tears collected preoperatively 1 5 days postoperatively....

Prognostic nutritional index (PNI) is a novel inflammation marker that useful in predicting prognosis of certain conditions. We aimed to study PNI the outpatient and inpatient subjects with established Covid-19 also compare deceased survived patients.The patients whom presented or clinics Abant Izzet Baysal University Hospital were enrolled study. levels inpatients outpatients, compared. values compared.Study population was consisted 4419 (2907 outpatients 1512 inpatients). (41.55...

Abstract. Purpose: Photorefractive keratectomy (PRK) induces free radical formation and polymorphonuclear (PMN) cell infiltration in the cornea. Vitamin E is a scavenger protects cells from reactive oxygen species. We investigated effects of topical vitamin on corneal PMN antioxidant enzyme activities after PRK. Methods: studied four groups, each consisting seven eyes. Group 1 were control In group 2 epithelium was removed by blunt spatula ( epithelial scrape ). 3, photoablation (59 µm, 5...

Aim: Cancer is still considered as one of the leading causes mortality worldwide. Various tumor factors have been used for diagnosis and follow-up solid tumors; however, their clinical features remains controversial in terms diagnostic, prognostic, predictive values. In this study, we aimed to investigate use systemic inflammatory response biomarkers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), lymphocyte-to-monocyte (LMR), tumors. Method: We...

A 3-arm, parallel group, randomized clinical trial examines the effect of aromatherapy through inhalation and foot massage on blood pressure stress response in patients with essential hypertension. Lavender oil reduced pressure, heart rate, serum cortisol, subjective anxiety hypertensive patients.

AbstractGlutathione related enzymes are involved in the metabolism and detoxification of cytotoxic carcinogenic compounds as well reactive oxygen species. Excimer laser is a very useful tool for treatment refractive errors removing superficial corneal opacities. Previous studies have shown that excimer may initiate free radical formation cornea. In present study, we evaluated effect keratectomy on glutathione-related enzyme activities rabbits. Animals were divided into five groups, all...

The Sysmex Coagulation System-2500 (CS-2500) is a fully automated coagulation analyzer that uses the optical reaction method. In this study, we aimed to evaluate performance characteristics of CS-2500 in two tests [prothrombin time (PT) and activated partial thromboplastin (aPTT)] at our hospital laboratory. PT aPTT measurements were performed using STA-Compact Diagnostica Stago coagulometers (STA-Compact). Then, precision, accuracy, reference range verification, method comparison statistics...

Aim: To investigate the protective efficacy of magnesium sulphate in a model rat liver ischemiareperfusion (I/R) injury.Method: 32 adult female Wistar-Albino rats (250 to 350 g) were used this experimental study.Rats divided into 4 groups according ischemia and sulfate application methods.Group 1 (C); control, group 2 (M); sulphate, 3 (I/R); I/R, (I/R+M); I/R + treated.The blood samples centrifuged for study aspartate aminotransferase (AST), alanine aminotransferase, prothrombin time (PT),...

Aim: To investigate the clinical effect of computer-aided sperm analyzers (CASA) by comparing low concentration semen samples evaluated CASA with count performed on Makler Counting Chamber (MC) as a manual method.Methods: Semen were taken from184 patients coming to our clinic (SQA-V Gold analyzer, MES Medical Electronic Systems Ltd.Caesarea Industrial Park, IL 3088900, UK) and MC (Makler Chamber, Sefi-Medical Instruments ltd., Haifa, Israel).Samples divided into two groups containing sperms...

Its increasing clinical importance has turned 25-hydroxy-Vitamin D (25(OH)D) into an indispensable test in laboratories. In this study, we aimed to analyze the analytical performances of two widely used immunoassays, namely new restandardized Abbott product Architect 25-OH Vitamin and Beckman Coulter Access 25(OH) Total Test by making comparisons with reference method liquid chromatography tandem mass spectrometry (LC-MS/MS).The I2000SR System (Abbott Laboratories, IL, USA; ref 5P02) Access2...

Evaluation of the analytical performance two vitamin D immunoassay methodsV itamin is a regulatory, bone-stimulating that has role in absorption calcium and inorganic phosphorus from intestine.A deficiency known to be risk factor for osteoporosis [1].The importance many chronic diseases, including cancer, diabetes, hypertension, asthma, as well bone, liver, kidney diseases also been demonstrated recent studies [2,3].This increased demand 25-hydroxyvitamin [25(OH)D] test routine measurement...

Background We aimed to analyze the analytical performance of Lifotronic H9 glycated hemoglobin analyzer (Lifotronic H9) with Arkray Adams HA-8160 (Arkray HA8160), which is currently used for measurement HbA1c test in our laboratory. Methods The verification studies were performed by comparison HA8160, has been verified and already laboratory, accordance CLSI EP5-A3 15-A3 guidelines. method study was 316 subjects. Results Both instruments demonstrated perfect repeatability (within-run) CVs...

Objective: The effect of wet cupping therapy on anxiety and thiol/disulfide homeostasis was evaluated in rats with premature ovarian failure (POF) induced by cyclophosphamide (CYC). Material Methods: Twenty four Wistar Albino female were divided into control (n=6), POF POF+wet (n=6) groups. CYC at a dose 200 mg/kg injected intraperitoneally to One week later, applied groups for 5 minutes. next day, Open Field Test Elevated Plus Maze all experimental evaluate anxiety. After sacrification,...

Background: The aim was to investigate the antioxidant effects of lycopene and caffeine in rats exposed renal ischemia/reperfusion injury. Materials Methods: Following right nephrectomy, 60 minutes ischemia followed by reperfusion were performed 200-250 gram Wistar albino used study. 30 before ischemia, (5 mg/kg), (50 mg/kg) + administered intraperitoneally rats. After experiment, 4 ml blood left kidney taken from Tissue malondialdehyde, glutathione peroxidase, superoxide dismutase serum...