- Inflammatory Biomarkers in Disease Prognosis
- Adipokines, Inflammation, and Metabolic Diseases
- Clinical Nutrition and Gastroenterology
- Anesthesia and Sedative Agents
- Cancer, Lipids, and Metabolism
- Streptococcal Infections and Treatments
- Liver Disease and Transplantation
- Thyroid Cancer Diagnosis and Treatment
- Hematological disorders and diagnostics
- Gastrointestinal disorders and treatments
- Cardiovascular Disease and Adiposity
- Nausea and vomiting management
- Acute Kidney Injury Research
- Abdominal vascular conditions and treatments
- Pancreatitis Pathology and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Autoimmune and Inflammatory Disorders
- Amoebic Infections and Treatments
- Respiratory Support and Mechanisms
- Enhanced Recovery After Surgery
- Biliary and Gastrointestinal Fistulas
- Mycobacterium research and diagnosis
- Intraperitoneal and Appendiceal Malignancies
- Chronic Kidney Disease and Diabetes
- Heme Oxygenase-1 and Carbon Monoxide
Bolu Abant İzzet Baysal University
2012-2023
Istanbul Memorial Hospital
2015
Adli Tıp Kurumu
2013
Summary Objective: Hashimoto's thyroiditis (HT) is an autoimmune inflammatory disorder. The purpose of this study was to determine the neutrophil-to-lymphocyte ratio (NLR), a novel marker inflammation, in patients with HT and compare these values those from healthy subjects. Method: A total 154 participants were included study, 90 64 volunteers. Retrospectively, demographic laboratory data subjects obtained our institution's database. Patients active infection, diabetes mellitus, malignancy,...
Hashimoto's Thyroiditis (HT) is the most common autoimmune thyroiditis worldwide and characterized with lymphomonocytic inflammation of thyroid gland. Red cell distribution width (RDW) reflects erythrocyte anisocytosis besides it increases in iron deficiency anemia, recent studies reported that RDW was also associated conditions overt or subclinical inflammation. We aimed to answer whether increased thyroiditis.Patients HT admitted outpatient clinic our hospital were included study. Patients...
Background: Type 2 diabetes mellitus and obesity are two important disorders which associated with the enormous amount of morbidity mortality. Inflammation plays a crucial role in development complications these diseases. Aim: We aimed to compare mean platelet volume (MPV) as an inflammatory marker well poorly controlled type diabetic subjects observe its association indices, body mass index (BMI) waist circumference. Method: Data patients obtained from institutional database retrospectively...
Possible pathophysiological mechanisms of irritable bowel syndrome (IBS) are interactions between microbial flora the gut and mucosal/systemic immune system, post-infectious status inflammation. Mean platelet volume (MPV) red cell distribution width (RDW) have been reported as inflammatory markers in patients with disease, but they not studied functional gastrointestinal disorders.To investigate whether there was an association haemogram parameters (RDW MPV) IBS.Forty IBS 44 healthy controls...
Many studies in literature point out that inflammation related to nasal polyp is mostly dependent on eosinophils and their inflammatory products. Beside eosinophils, platelets may have a role development. Platelets are involved haemostasis, tissue repairing inflammation. However, our knowledge, there no reports the study association between platelet parameters polyps.Forty-three patients with polyps forty-nine healthy controls were enrolled study, retrospectively. Laboratory data of obtained...
Background . Red cell distribution width (RDW) has been used as a marker of iron deficiency; however, it is accepted cardiovascular survival. We aimed to study RDW levels in hemodialysis (HD) patients and the association between inflammatory, nutritional, volume markers. Methods included 296 HD with sufficient storage without anemia or hypervolemia. grouped into four groups according clinical parameters, albumin, C-reactive protein (CRP). Results The lowest were found group 1 (13.2%)....
Purpose: Kidney Injury Molecule-1 is a protein that increases in urine following tubular damage. levels were correlated with the level of chronic kidney disease secondary to diabetic nephropathy patients type 2 Diabetes Mellitus. Methods: Clinical and laboratory findings 142 34 control subjects analysed. Creatinine HbA1c blood samples albumin, creatinine assessed. Results: Urinary significantly increased both subgroups (normo-/micro-/macro-albuminuria) (stage 2-4) compared controls. stage...
We aimed to study the efficacy of three surgical flap techniques in pilonidal surgery. Pilonidal disease is characterized by chronic inflammation and infection sacrococcygeal region. Complications recurrence are common after treatment optimal for has not been established yet. enrolled a total 401 patients this study. Patients have treated with Karydakis (n = 113), modified Limberg 179), or 109) techniques. Mean off-work period, time walk without pain, sit on toilet, take drainage catheter...
Aim: A lot of studies are being carried out to predict recurrence and metastasis in rectal cancer, which is a common type cancer general surgery practice. It thought that MLR (monocyte lymphocyte ratio) , an indice developed by division monocyte count count, may be good marker reflect the degree tumor progression prognosis. In our study, we investigated role predicting cancer.Materials Methods: Fifty-seven patients diagnosed with Abant Izzet Baysal University clinic between 2012 2016 were...
Hydatid cyst disease is a common worldwide zoonosis. Most of the cysts are located in liver. Abscess formation due to infection an important complication. M. morganii, Gram-negative Bacillus , quite rare cause liver abscess. A 77-year-old woman was admitted hospital with complaints fever, chills, nausea, vomiting, loss appetite, and abdominal pain right-upper quadrant. Her history positive for hepatic hydatid ten years ago. Physical examination revealed painful mass filling quadrant...
Many of studies have shown that increased lipid levels play a significant role in the pathogenesis atherosclerosis after splenectomy. We investigated effects N-acetyl cysteine (NAC) on parameters and leukocyte platelet (PLT) following splenectomy.32 Sprague-Dawley rats weighing from 200 to 250 g were placed into four experimental groups. For 42 days post-operatively, all fed standard rat food water first group ( n = 8) received no intraperitoneal infusion. Rats second 6) given 50 mg/kg...
The diagnosis of acute appendicitis is based on medical history and physical examination. Serum (S) amiloid A (AA) levels are elevated in many inflammatory conditions. Omentin a recently discovered adipokine showing decreased associated with We aimed to measure SAA omentin patients appendicitis.36 30 healthy subjects were enrolled this research study. statistical analysis was performed using IBM SPSS Statistics Version 16.0 (SPSS Inc.®, Chicago, IL, United States).Patients study group...
Amaç: Kritik hastaların bakım ve tedavisi sırasında enteral beslenme, enerji ihtiyacının karşılanması, vücut direncinin korunması, gastrointestinal sistem (GİS) florasının korunması translokasyonların önlenmesi açısından çok önemlidir.Bu çalışmadaki amacımız; hastanemizde PEG takılması planlanan takılma endikasyonlarını, işlem sonrası komplikasyonlarını
Yag dokusu gunumuzde enerji metabolizmasinin onemli bir parcasi olarak kabul edilmektedir. Salgiladigi adipokinler beslenme, istah, dengesi, insulin ve glukoz metabo- lizmasi, lipid metabolizmasi, kan basincinin duzenlenmesi, vaskuler remodeling, koagulasyon, inflamasyon gibi vucudun bircok fizyolojik isleminde rol oynamaktadirlar. Leptin, cev- resel etmenler genler beraberce vucut yag miktarini duzenlemektedirler. Leptin molekulunun su ana kadar agirligi, dengesi takim noroendokrin...
Liver transplantation (LT) has become a favorable therapeutic option for patients with end-stage liver diseases. Gilbert's syndrome (GS) is benign condition characterized by intermittent mild jaundice due to unconjugated hyperbilirubinemia. It not obvious whether living-donor (LDLT) from donor GS could result in normal outcome both the recipient and donor. We aimed determine right lobe hepatectomy safe procedure living donors LT recipients. Between September 2011 March 2015, 305 LDLT...
The aim of this study is to investigate the effects bispectral index-controlled use magnesium on propofol consumption, periprocedural hemodynamic response and patient comfort.A total 60 patients were enrolled in study. In Group 1 (magnesium), a single dose 50 mg/kg sulfate diluted with 100 mL 0.9% NaCl was administered 10 minutes before beginning procedure. Initially bolus 0.5 applied. maintenance mcg/kg/min. During procedure, infusion increased by titration until index (BIS) value 70...
Aim: To investigate the protective efficacy of magnesium sulphate in a model rat liver ischemiareperfusion (I/R) injury.Method: 32 adult female Wistar-Albino rats (250 to 350 g) were used this experimental study.Rats divided into 4 groups according ischemia and sulfate application methods.Group 1 (C); control, group 2 (M); sulphate, 3 (I/R); I/R, (I/R+M); I/R + treated.The blood samples centrifuged for study aspartate aminotransferase (AST), alanine aminotransferase, prothrombin time (PT),...
Complications after colorectal surgery have not been reduced in recent years. Anastomotic leakage is responsible for nearly all morbidity colonic and about one third of the mortality.For study, 34 albino Wistar rats (about 155-190 g weight) were divided into four experimental groups. Each underwent an abdominal incision resection colon 4 cm distal to cecum form a colo-colonic anastomosis. In post-operative period, first group (n=8) fed with standard rat food water, second (n=9)...
Aim: To investigate the co-existence of cholelithiasis in patients with gastrointestinal (GI) cancer both preoperative and postoperative periods.Methods: We retrospectively analyzed data who underwent GI tract surgery general clinic a university hospital between January 2013 December 2019 for presence 'cholelithiasis' periods.Age, gender, tumor type localization were determined.In addition, cases divided into two as upper lower according to location relationship was evaluated.Results: A...
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