Tuba Taslamacıoğlu Duman

ORCID: 0000-0002-3836-2125
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Research Areas
  • Inflammatory Biomarkers in Disease Prognosis
  • Gout, Hyperuricemia, Uric Acid
  • Adipokines, Inflammation, and Metabolic Diseases
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Diabetes Treatment and Management
  • Liver Disease Diagnosis and Treatment
  • Cardiovascular Disease and Adiposity
  • Chronic Kidney Disease and Diabetes
  • Diabetes and associated disorders
  • Diabetes Management and Research
  • Nutrition and Health in Aging
  • Pharmacology and Obesity Treatment
  • Thyroid Disorders and Treatments
  • Alcohol Consumption and Health Effects
  • Pancreatic function and diabetes
  • COVID-19 Clinical Research Studies
  • Blood Pressure and Hypertension Studies
  • Metabolism, Diabetes, and Cancer
  • Pancreatitis Pathology and Treatment
  • Venous Thromboembolism Diagnosis and Management
  • Vitamin D Research Studies
  • Bone and Joint Diseases
  • Iron Metabolism and Disorders
  • Muscle and Compartmental Disorders
  • Vitamin C and Antioxidants Research

Bolu Abant İzzet Baysal University
2018-2024

Background: Type 2 diabetes mellitus is associated with chronic low grade inflammation. One of the novel inflammatory mark- ers hemogram derived neutrophil to lymphocyte ratio (NLR). Objective: We aimed compare NLR levels diabetic subjects and healthy controls observe possible correlation be- tween HbA1c.Methods: Medical data type admitted out-patient clinics our institution between April July in 2017 were obtained from database retrospectively analyzed. Control group was chosen who visited...

10.4314/ahs.v19i1.35 article EN African Health Sciences 2019-04-18

Despite it has some disadvantages, the most important marker of diabetic control is glycated hemoglobin (HbA1c). Uric acid to HDL cholesterol ratio (UHR) a promising in metabolic syndrome. We aimed compare UHR levels well and poorly controlled type 2 male subjects, as healthy men, observe its correlation with other parameters.Male patients T2DM that showed up outpatient internal medicine clinics our hospital were enrolled study. Diabetic subjects divided into two groups according level...

10.1080/13685538.2019.1678126 article EN The Aging Male 2019-10-16

The diagnosis and follow-up of hypertension (HT) depend on the blood pressure measurements, which can be affected by several factors. In present work, we aimed to explore role uric acid/HDL-cholesterol ratio (UHR) in HT whether/or not it was associated with poor control.In this retrospective cross-sectional cohort study, all participants treated for then followed up internal medicine clinics our institution were enrolled. Hypertensive patients grouped as either poorly or well-controlled...

10.1080/00325481.2022.2039007 article EN Postgraduate Medicine 2022-02-10

Diabetic kidney injury (DKI) is a serious microvascular complicationof type 2 diabetes mellitus (T2DM). Novel markers are being developedto make timely diagnosis of this complication. Uric Acid to HDLratio (UHR) was reported be associated with inflammatory andmetabolic diseases such as metabolic syndrome, diabetesmellitus, thyroiditis, and nonalcoholic hepatosteatosis, recently. Inthe present study, we aimed show the diagnostic role UHR indiabetic (DKI), condition characterized chronicand...

10.1080/00325481.2023.2214058 article EN Postgraduate Medicine 2023-05-12

OBJECTIVES: The objective of this study was to identify a parameter that can facilitate the diagnosis prediabetes and predict likelihood its development in individuals at high risk.METHODS: In retrospective study, population selected from Bolu Abant Izzet Baysal University Hospital's patients.Participants were divided into two groups, healthy group.We excluded with certain conditions or taking medications.The compared ratios uric acid high-density lipoprotein (HDL) between groups identified...

10.4149/bll_2023_130 article EN Bratislavské lekárske listy/Bratislava medical journal 2024-01-01

Metabolic syndrome (MS) is a clinical entity that associated with increased risk of type 2 Diabetes Mellitus (DM) and cardiovascular diseases. Serum uric acid levels are correlated MS criteria. We hypothesized whether to HDL-cholesterol ratio (UHR) could predict diabetic regulation presence in subjects.Admissions the subjects DM outpatient clinics our institution were retrospectively analyzed. Study population grouped into well-controlled poorly controlled diabetics according HbA1c level...

10.1590/1806-9282.65.1.9 article EN Revista da Associação Médica Brasileira 2019-01-01

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Aktas G, Duman TT, Atak BM, et al. Irritable bowel syndrome is associated with novel inflammatory markers derived from hemogram parameters. Family Medicine & Primary Care Review. 2020;22(2):107-110. doi:10.5114/fmpcr.2020.95311. APA Aktas, G., Duman, T. T., Atak, B. M., Kurtkulagi, O., Bilgin, S., Basaran, E. (2020). Review, 22(2), 107-110. https://doi.org/10.5114/fmpcr.2020.95311 Chicago Gulali, Tuba T Burcin...

10.5114/fmpcr.2020.95311 article EN cc-by-nc-sa Family Medicine & Primary Care Review 2020-01-01

SUMMARY OBJECTIVE Association between type 2 diabetes mellitus and inflammation is well-established. We aimed to study platelet-to-lymphocyte ratio (PLR), a novel inflammatory index derived from hemogram, in diabetic patients comparison those healthy volunteers. METHODS Medical data of diabetics that showed up general outpatient medical clinics our institution February 2017 August were recorded analyzed. RESULTS Median PLR was significantly higher than the controls (p=0.001). Moreover,...

10.1590/1806-9282.65.1.38 article EN Revista da Associação Médica Brasileira 2019-01-01

Hemogram indices were proposed as novel inflammatory markers in chronic conditions and inflammation has substantial role the pathogenesis of type 2 diabetes mellitus (T2DM). We aimed to observe hemogram parameters diabetic male subjects with various age groups well poorly controlled subsets.Data men enrolled study recorded from patient files institution. Study population grouped into three according age. Group A was consisted patients younger than 55 years, B aged between 64 C 65 years or...

10.1080/13685538.2019.1632283 article EN The Aging Male 2019-06-28

SUMMARY OBJECTIVE: Non-alcoholic fatty liver disease, which is characterized by lipid being deposited into hepatocytes, affects nearly one in three adults globally. Inflammatory markers were suggested to be related with hepatic steatosis. Uric acid HDL cholesterol ratio proposed as a novel inflammatory and metabolic marker. We aimed compare levels of patients disease those healthy controls find out potential correlations between other disease. METHODS: Patients diagnosis who on clinical...

10.1590/1806-9282.20201005 article EN Revista da Associação Médica Brasileira 2021-04-01

Background: Type 2 diabetes mellitus and obesity are two important disorders which associated with the enormous amount of morbidity mortality. Inflammation plays a crucial role in development complications these diseases. Aim: We aimed to compare mean platelet volume (MPV) as an inflammatory marker well poorly controlled type diabetic subjects observe its association indices, body mass index (BMI) waist circumference. Method: Data patients obtained from institutional database retrospectively...

10.15562/bmj.v7i3.806 article EN Bali Medical Journal 2018-10-03

Neuregulin-4 (Nrg-4) is a new adipokine released from brown adipose tissue. It plays pivotal role in regulating systemic energy balance, glucose and lipid metabolism reducing chronic inflammation. We aimed to investigate the relation between diabetic microvascular complications (DMC) serum levels patients with type 2 diabetes mellitus.Patients mellitus were divided into DMC without (non-DMC). Nrg-4 of compared.Fifty 29 enrolled non-DMC groups, respectively. was 1.23 (0.02-5.1) ng/mL 2.5...

10.1111/eci.13206 article EN European Journal of Clinical Investigation 2020-01-30

Background. Hashimoto's thyroiditis (HT) is an auto-immune condition characterized with lymphocytic and fibroblastic infiltration of the thyroid gland. The rate uric acid HDL cholesterol - so called as to ratio (UHR) has been shown be elevated in inflammatory conditions diseases. We aimed compare UHR other laboratory parameters patients HT those values healthy controls. Methods. diagnosed by medical history, physical examination, autoantibodies serum characteristic sonographic findings...

10.2478/rjim-2021-0023 article EN cc-by-nc-nd Romanian Journal of Internal Medicine 2021-06-18

The systemic inflammatory index (SII) is a new marker that has been the subject of various studies in diseases with chronic inflammation. Diabetic nephropathy disease associated We aimed to evaluate relationship between SII and diabetic nephropathy.Patients diabetes who applied our outpatient clinic were included study. patients divided into two groups: those without. In addition, healthy individuals for general check-ups during these dates as control group. values other characteristics...

10.3390/diagnostics13122063 article EN cc-by Diagnostics 2023-06-14

Hashimoto's thyroiditis (HT) is a chronic autoimmune that causes systemic inflammation in the body, leading to hypothyroidism and an enlargement of thyroid gland.This study aims reveal whether there relationship between platelet-count-to-lymphocyte-count ratio (PLR), which used as new inflammatory marker.In this retrospective study, we compared PLR euthyroid HT group hypothyroid-thyrotoxic controls. We also evaluated values thyroid-stimulating hormone (TSH), free T4 (fT4), C-reactive protein...

10.3390/diseases11010015 article EN cc-by Diseases 2023-01-22

C-reactive protein-to-lymphocyte ratio is a reliable marker in patients with COVID-19 infection: the CLEAR COVID study La relación proteína C-reactiva-a-linfocito es un marcador confiable en pacientes con infección

10.24875/cirue.m22000545 article EN Cirugía y Cirujanos (English Edition) 2024-03-12

To compare mean platelet volume to lymphocyte ratio (MPVLR) of diabetic nephropathy subjects those diabetics without nephropathy.Observational, cross-sectional study.Tertiary referral hospital, in Bolu, Turkey, from July December 2017.Patients with type 2 diabetes mellitus admitted the Internal Medicine Clinic, were included. Patients divided into two groups according urinary microalbumin/creatinine ratio: and non-nephropathy group. MPVLR was calculated mathematically by division MPV...

10.29271/jcpsp.2018.11.844 article EN Journal of College of Physicians And Surgeons Pakistan 2018-10-29

Neuregulin-4 is a cytokine with many functions and primarily produced by fat tissue.The aim of the study was to observe relationship between serum neuregulin-4 levels diabetes regulation in type 2 mellitus (T2DM), compare diabetic subjects those healthy controls.Patients T2DM were included study. Healthy enrolled as controls. Subjects glycated haemoglobin (HbA1c) <7% classed well controlled HbA1c >7% poorly controlled. control groups compared.The T2DM, well-controlled significantly different...

10.4414/smw.2019.20139 article EN cc-by Schweizerische medizinische Wochenschrift 2019-10-27

Chronic hepatitis C (CHC) is one of the most important health problems affecting significant rate world population and it may lead to cirrhosis hepatocellular carcinoma. C-reactive protein lymphocyte count ratio (CLR) used in estimating inflammatory burden. Therefore, this study aimed compare CLR values between CHC patients healthy controls with without fibrosis.Patients infection who visited outpatient inpatient internal medicine clinics our institution January 2021 December were enrolled...

10.1590/1806-9282.20220236 article EN Revista da Associação Médica Brasileira 2022-06-01

SUMMARY OBJECTIVE In this study, we aimed to analyze the relationship between serum uric acid (UA) and microalbuminuria as a marker of renal injury in type 2 diabetes mellitus. METHODS A total 100 patients with mellitus were enrolled study. Participants divided into two groups according urinary microalbumin/creatinine ratio: diabetic nephropathy non-nephropathy group. UA compared study groups. RESULTS Serum levels significantly higher than those group (UA groups: 6.3 (1.82) mg/dl,...

10.1590/1806-9282.65.9.1156 article EN Revista da Associação Médica Brasileira 2019-09-01

OBJECTIVES: Frailty is a common problem in patients with type 2 diabetes mellitus (T2DM).It considered to be associated infl ammation.Novel markers derived from hemogram, such as neutrophil/lymphocyte ratio (NLR) and mean platelet volume/lymphocyte (MPVLR), are proposed ammatory markers.In present study, we aimed compare NLR MPVLR levels of frail T2DM non-frail diabetic subjects.METHODS: Diabetic subjects were grouped groups according the Edmonton Frail Scale.General characteristics...

10.4149/bll_2021_017 article EN Bratislavské lekárske listy/Bratislava medical journal 2021-01-01

Background: Frailty is associated with increased risk of hospitalization in diabetic patients. Both SARS-CoV-2 pandemic and type 2 diabetes mellitus contribute to the frailty. In this study we aimed observe clinical laboratory indices subjects during COVID-19 who were either frail or not according Edmonton score. Material methods: During era, 100 consecutive patients divided into two groups as non-frail Frail Scale scores. Laboratory features compared. Results: older than diabetics. Blood...

10.5603/dk.a2022.0015 article EN cc-by-nc-nd Clinical Diabetology 2022-04-20
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