- Ophthalmology and Eye Disorders
- Pituitary Gland Disorders and Treatments
- Nasolacrimal Duct Obstruction Treatments
- Glaucoma and retinal disorders
- Oral and Maxillofacial Pathology
- Head and Neck Surgical Oncology
- Thyroid Disorders and Treatments
- Cerebral Venous Sinus Thrombosis
- Salivary Gland Tumors Diagnosis and Treatment
- Retinal and Optic Conditions
- Corneal surgery and disorders
- Child Abuse and Related Trauma
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Ocular Diseases and Behçet’s Syndrome
- Sinusitis and nasal conditions
- Intraocular Surgery and Lenses
- IgG4-Related and Inflammatory Diseases
- Retinal Diseases and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Ocular Oncology and Treatments
- Advanced Differential Geometry Research
- Congenital limb and hand anomalies
- Ocular Disorders and Treatments
- Ophthalmology and Visual Impairment Studies
Gazi University
2014-2024
University of Health Sciences Antigua
2024
Sağlık Bilimleri Üniversitesi
2024
Kırıkkale University
2021
Gazi Hastanesi
2014
Graves' orbitopathy (GO) is the main extrathyroidal manifestation of disease (GD). Choice treatment should be based on assessment clinical activity and severity GO. Early referral to specialized centers fundamental for most patients with Risk factors include smoking, thyroid dysfunction, high serum level thyrotropin receptor antibodies, radioactive iodine (RAI) treatment, hypercholesterolemia. In mild active GO, control risk factors, local treatments, selenium (selenium-deficient areas) are...
Graves' orbitopathy (GO) is an autoimmune condition, which associated with poor clinical outcomes including impaired quality of life and socio-economic status. Current evidence suggests that the incidence GO in Europe may be declining, however data on prevalence this disease are sparse. Several variants exist, euthyroid GO, recently listed as a rare (ORPHA466682). The objective was to estimate its Europe, based available literature, consider whether they potentially qualify rare. Recent...
<h3>Background/aims</h3> The epidemiology of Graves’ orbitopathy (GO) may be changing. aim the study was to identify trends in presentation GO tertiary centres and initial management over time. <h3>Methods</h3> Prospective observational European Group On Orbitopathy (EUGOGO) centres. All new referrals with a diagnosis 4-month period 2012 were included. Clinical demographic characteristics, referral timelines decisions about recorded. data compared similar EUGOGO survey performed 2000....
To construct a predictive score for the development or progression of Graves' orbitopathy (GO) in hyperthyroidism (GH).Prospective observational study patients with newly diagnosed GH, treated antithyroid drugs (ATD) 18 months at ten participating centers from EUGOGO 8 European countries.348 were included untreated GH but without obvious GO. Mixed effects logistic regression was used to determine best predictors. A (called PREDIGO) constructed.GO occurred 15% (mild 13% and moderate severe...
Background Graves’ orbitopathy (GO) is subject to epidemiological and care-related changes. Aim of the survey was identify trends in presentation GO European Group On Orbitopathy (EUGOGO) tertiary referral centres initial management over time. Methods Prospective observational multicentre study. All new referrals with diagnosis within September–December 2019 were included. Clinical demographic characteristics, timelines therapeutic decisions recorded. Data compared a similar EUGOGO performed...
To compare the reduction of proptosis and incidence new-onset diplopia after 3-wall (medial, lateral, inferior) orbital decompression versus balanced medial lateral wall combined with fat excision in patients Graves ophthalmopathy.Three-wall including medial, inferior, walls was performed 13 eyes 7 (group 1), removal 18 11 2). A transnasal endoscopic approach used for removal. canthotomy incision a short upper eyelid extended removal, this an inferior conjunctival fornix when floor...
<i>Background:</i> To evaluate possible causative factors of unsuccessful dacryocystorhinostomy (DCR) surgery, and present the surgical technique results revision external DCR in a tertiary referral center. <i>Methods:</i> During 2001–2007, 79 patients (59 female, 20 male, 83 revised sites) underwent for management recurrent epiphora after surgery. The reasons surgery were noted according to preoperative nasal endoscopic perioperative findings, was performed address...
Purpose: To compare the long-term visual outcomes after 2-wall (medial-lateral) versus 3-wall (medial-lateral-inferior) orbital decompression combined with fat removal in patients dysthyroid optic neuropathy (DON).Methods: Records of 68 eyes 42 were retrospectively reviewed. Two-and was performed 41 and 27 eyes, respectively. Transcaruncular approach used for medial wall decompression. Lateral canthotomy upper eyelid crease incision lateral removal, transconjunctival lower if floor...
Purpose: To investigate the effects of combined orbital bone and fat decompression on intraocular pressure (IOP) superior ophthalmic vein blood flow velocity (SOV-BFV), their association with clinical features Graves orbitopathy (GO).Methods: During 2002–2008 period, 72 eyes 36 GO cases demonstrating moderate to severe were evaluated according as: or without dysthyroid optic neuropathy (DON), underwent decompression. A control group comprised 40 20 healthy subjects. In both groups, a full...
Purpose: To investigate the oxidative stress and antioxidant activity in orbit Graves' ophthalmopathy (GO). Materials Methods: Orbital fibroadipose tissue samples were obtained from 13 cases during orbital fat decompression surgery. All demonstrated features of moderate or severe GO according to European Group on Orbitopathy classification. The disease was evaluated with Clinical Activity Score, clinical Ophthalmopathy Index. 8 patients without any thyroid autoimmune studied as controls. In...
AIM: To evaluate the long-term results of different orbital decompression techniques performed in patients with Graves' ophthalmopathy (GO). METHODS: Totally 170 cases GO underwent between 1994 and 2014. Patients were divided into 4 groups as medial-inferior, medial-lateral (balanced), medial-lateral-inferior, lateral only according to applied surgical technique. Surgical indications, regression degrees on Hertel exophthalmometer, new-onset diplopia primary gaze gaze-evoked after surgery...
Abstract Purpose Patients with Graves’ orbitopathy can present asymmetric disease. The aim of this study was to identify clinical characteristics that distinguish from unilateral and symmetric orbitopathy. Methods This a multi-centre new referrals 13 European Group on Orbitopathy (EUGOGO) tertiary centres. New patients presenting over 4 month period diagnosis were included. Patient demographics collected examination performed based previously published protocol. categorized as having...
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ABSTRACT PURPOSE: We studied the long-term results of photorefractive keratectomy (PRK) in keratoconus suspects detected by videokeratography (TMS). METHODS: Bilateral inferior corneal steepening was 6 candidates for PRK presenting with moderate myopia or astigmatism. Mean follow-up 44.5 ± 4.4 months (range, 38 to 54 mo). spherical equivalent refraction -5.18 1.60 D (mean sphere, -4.73 D; mean cyclinder, -0.92 D) which stable at least preceding year. The quantitative measurement (I-S value)...
To give the long-term success rates of punctal dilatation with insertion perforated plugs (PPP) for management acquired stenosis.A series 44 eyes 26 patients who underwent PPP implantation stenosis were retrospectively evaluated in terms severity stenosis, associated eyelid disorders, technique PPP, and rate treatment epiphora. In all patients, dilation was performed prior to plugs. Patients demonstrating moderate or severe horizontal laxity a lateral tarsal strip procedure before...
Most imaging techniques used for the evaluation of obstructive epiphora, such as DS DCG, rely on undesired ionizing radiation. We evaluated efficacy topical contrast-enhanced MR DCG in comparison with patients epiphora who underwent balloon or stent placement.Thirty-six LDSs 21 treated (n = 11) placement were examined and DCG. Contralateral 14) also unilateral disease. A sterile 0.9% NaCl solution containing 1:100 diluted gadolinium chelate was instilled into conjunctival sacs. The 3D FSPGR...
To investigate the level of ascorbic acid in human tear fluid after photorefractive keratectomy (PRK), transepithelial PRK, and laser situ keratomileusis (LASIK).Departments Ophthalmology Biochemistry, School Medicine, Gazi University, Ankara, Turkey.Twenty patients (7 women 13 men) were included this study. Traditional PRK with epithelial scraping by a blunt spatula followed surface ablation eyes), or LASIK (6 eyes) was performed. Tears collected preoperatively 1 5 days postoperatively....
To evaluate etiologies, demographics, and surgical outcomes in cases of traumatic nasolacrimal duct obstruction (NLDO).Charts 35 patients with the diagnosis NLDO were reviewed retrospectively. Patient type trauma, previous lacrimal surgery history, treatment, follow-up time, anatomical functional evaluated.Forty eyes included this study over 12 years. Twenty-four male (68.5%) mean age was 31.52 ± 14.58 years (range 9-68). The most common etiology motor vehicle accidents (52.5%), followed by...
In Brief Purpose To evaluate the results of nasolacrimal polyurethane stent implantation for treatment primary acquired duct obstruction and effects obstructed on subsequent dacryocystorhinostomy (DCR). Methods This study was designed as a nonrandomized, prospective clinical trial. Stent attempted in 53 lacrimal drainage systems 47 patients. placement performed retrograde fashion through external nare over guide wire, which introduced from upper punctum. Occluded stents were removed either...
KONUK, ONUR MD; ÖZDEK, ŞENGÜL ÖNAL, BARAN TIFTIKÇIOĞLU, YUDUM GÜRELIK, GÖKHAN HASANREISOĞLU, BERATI MD Author Information
The aim of this study is to evaluate the expression cycloocygenase-2 (COX-2) in orbital fibroadipose connective tissue Graves' ophthalmopathy (GO) patients, and investigate associations between COX-2 GO characteristics.The tissues 23 cases demonstrating moderate or severe GO, eight control subjects without any history thyroid autoimmune disease were analyzed for mRNA expression. Real-time relative quantitative PCR was performed assess transcripts using LightCycler. activity evaluated by...