A5001258035- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Meningioma and schwannoma management
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrospinal fluid and hydrocephalus
- Pelvic floor disorders treatments
- Neurofibromatosis and Schwannoma Cases
- Urinary Bladder and Prostate Research
- Manufacturing Process and Optimization
- Advanced Radiotherapy Techniques
- Neurosurgical Procedures and Complications
- Glioma Diagnosis and Treatment
- BIM and Construction Integration
- Advanced MRI Techniques and Applications
- Ethics in Clinical Research
- Trigeminal Neuralgia and Treatments
- Biomedical Ethics and Regulation
- Medical Imaging Techniques and Applications
- Anorectal Disease Treatments and Outcomes
- Quality and Management Systems
- Risk and Safety Analysis
- Hernia repair and management
- Innovations in Concrete and Construction Materials
- Design Education and Practice
University of Stuttgart
2021-2025
Daimler (Germany)
2015-2017
Copernicus Therapeutics (United States)
2016
Dana (United States)
2016
Bupa Cromwell Hospital
2013
Royal Hallamshire Hospital
1992-2007
University of Washington
2003
Novem (Netherlands)
2001
Elekta (United States)
1999
Queen Square Radiosurgery Centre
1999
✓ The quality of survival 150 patients with arteriovenous malformations the brain is presented. mean period follow-up was over 15 years. surgically operated and conservatively managed groups are compared, a comparison that in long run appears to favor cases. results discussed indications for surgery summarized.
✓ Four-vessel angiography was repeated in 56 patients with confirmed subarachnoid hemorrhage whom the initial investigation negative. Only one aneurysm demonstrated. The results suggest that, good technique, careful observation, and a complete four-vessel cerebral angiography, false negative rate of less than 2% can be achieved. It is suggested that to repeat pan-angiography seldom justified unless further bleeding episodes occur.
This phantom study assesses the accuracy of stereotactic localization using Leksell G frame (Elekta Instruments AB, Stockholm, Sweden) with T1-weighted magnetic resonance imaging (Siemens 1.5 T Magnetom; Erlangen, Germany). The coordinates an array solid perspex rods were determined and compared measured values in a series transverse, coronal, sagittal images. maximum absolute errors observed (X = 2.7 mm, Y 7.0 Z 8.0 mm) discouraging. However, more reasonable mean 0.4 0.7 1.3 reflect...
OBJECTIVE--To observe the effects of stimulation sacral anterior roots on anorectal and low colonic pressures to programme implanted stimulators produce defecation. DESIGN--Prospective study 12 consecutive patients. SETTING--Spinal injuries unit university gastrointestinal physiology department. PATIENTS--12 Patients with complete supraconal spinal cord lesions. Their had been sustained at least two years before study. INTERVENTIONS--A Brindley-Finetech intradural root stimulator was in all...
Abstract OBJECTIVE Microsurgical resection of a cavernous malformation (CM) with or without associated cortical can provide efficient treatment drug-resistant epilepsy. To explore the potential alternative role radiosurgery and to evaluate its safety efficacy for this indication, we conducted retrospective multicenter study. METHODS We retrospectively reviewed files patients long-lasting epilepsy, presumably caused by CM, who were treated gamma knife (GK) surgery control their epilepsy in...
Abstract In coreless filament winding, resin-impregnated fibre filaments are wound around anchor points without an additional mould. The final geometry of the produced part results from interaction fibres in space and is initially undetermined. Therefore, success large-scale composite structures for architectural applications relies on reciprocal collaboration simulation, fabrication, quality evaluation, data integration domains. correlation those domains enables optimization design towards...
Abstract Fiber-reinforced composites offer innovative solutions for architectural applications with high strength and low weight. Coreless filament winding extends industrial processes, reduces formwork, allows tailoring of fiber layups to specific requirements. A previously developed computational co-design framework coreless is extended toward the integration reciprocal design feedback maximize flexibility inform decisions throughout process. multi-scalar representation introduced,...
The stereotactic radiosurgery unit in Sheffield became operational September 1985 and over 180 patients harbouring AVMs have been treated. first 52 underwent one year follow up angiography comprise the material for this study. At 26 (50%) already had a favourable outcome (16 complete 10 almost obliteration). results were same two sexes. There was better response younger patients: under 20 years 75% favourable, between 40 45% above about 25% favourable. Malformations lateral position appeared...
To investigate the potential of novel magnetic resonance (MR) angiographic techniques for assessment cerebral arteriovenous malformations.Forty patients who were about to undergo stereotactic radiosurgery prospectively recruited. Three-dimensional, sliding-slab interleaved ky (SLINKY), time-of-flight acquisition was performed, as a dynamic MR digital subtraction angiography (DSA) procedure in which single thick slices (6-10 cm) obtained using radiofrequency spoiled Fourier-acquired...
✓ A case of spontaneous intra-aneurysmal thrombosis, verified angiographically, is reported in a patient with subarachnoid hemorrhage and without surgical intervention. The frequency such an occurrence the factors involved are reviewed discussed.
The degree of static indeterminacy and its spatial distribution characterize load-bearing structures independent a specific load case. redundancy matrix stores the on main diagonal, thereby offers possibility to use this property for assessment structures. It is especially suitable be used in early planning stages design exploration. In paper, performance indicators with respect robustness assemblability are derived from matrix. For each indicators, detailed matrix-based derivation given...
Abstract. Fourteen patients with posterior uveal melanomas were treated using single fraction stereotactic radiosurgery. In each case a dose of 70 Gy was administered to the periphery tumour. Regression tumour has been observed in 13 patients, whilst lesion remained unchanged one patient. The visual acuity deteriorated all 14 patients. Significant radiation induced adverse reactions noted and include; retinopathy, optic neuropathy, rubeosis iridis, secondary glaucoma. Two have required...
To examine the structural changes in arteriovenous malformations (AVMs) after stereotactic radiosurgery and to identify cytoskeletal antigen phenotype of proliferating cells gain information about possible mechanism obliteration.We conducted immunohistochemical electromicroscopic investigations surgical material that was removed from seven patients. The patients were harboring cerebral AVMs had been previously treated with gamma knife irradiation, they experienced subsequent bleeding 10 52...
AbstractStereotactic radiosurgery has become one of the most acceptable means treating deep-seated intracranial arteriovenous malformations, as well being a useful adjunct in number other pathologies. One hundred and sixty patients are discussed, having follow-up at least 2 years. Radionecrosis occurred six haemorrhage latent period prior to thrombo-obliteration further six. Successful was ultimately achieved 76% patients. As bonus, epilepsy improved 29 48 presenting with seizures worsened...
OBJECTIVE: To compare the accuracy of stereotactic localization using magnetic resonance imaging (Siemens 1.5-T Magnetom; Siemens, Erlangen, Germany) with two-dimensional and three-dimensional data acquisition techniques. METHODS: A phantom study was performed in which coordinates an array rods were determined from images both studies compared measured values a series transverse, coronal, sagittal images. RESULTS: The results demonstrated distinct advantage acquisition; error greater than 2...
We report the results of treatment with radiosurgery 29 tumours in 27 patients acoustic neuromas between 1986 and 1989. The median follow-up was 6.6 years. appears to be an effective alternative surgery for 3 cm diameter or less. mortality morbidity presentation cranial nerve function is comparable very best surgical results. Every patient neuroma should informed about this direct surgery.
Data were obtained from 191 women with cerebral arteriovenous malformations (AVMs) referred for stereotactic radiosurgery the Leksell Gamma Unit in Sheffield. The risk of bleeding during pregnancy was examined and related to different trimesters these women. Some tentative guidelines are suggested advising AVMs, who become pregnant.