A5050218555- Mesenchymal stem cell research
- Pancreatic and Hepatic Oncology Research
- Cancer survivorship and care
- Epigenetics and DNA Methylation
- SARS-CoV-2 and COVID-19 Research
- Global Cancer Incidence and Screening
- BRCA gene mutations in cancer
- Cancer Cells and Metastasis
- Patient-Provider Communication in Healthcare
- Wound Healing and Treatments
- Immune cells in cancer
- Gastrointestinal Tumor Research and Treatment
- Breast Cancer Treatment Studies
- Palliative Care and End-of-Life Issues
- Extracellular vesicles in disease
Mexican Social Security Institute
2015-2024
Centro Medico Nacional Siglo XXI
2020
Macrophages with the M2 phenotype promote tumor development through immunosuppression of antitumor immunity. We previously demonstrated presence mesenchymal stem/stromal cells (MSCs) in cervical cancer (CeCa-MSCs), suggesting an immune protective capacity tumors, but to date, their effect modulating macrophage polarization remains unknown. In this study, we compared capacities MSCs from normal cervix (NCx) and CeCa a coculture system. Our results that CeCa-MSCs, contrast NCx-MSCs,...
PURPOSE The Instituto Mexicano del Seguro Social is a tripartite contribution providing care to more than 74 million beneficiaries, representing 50% of the country's general population. This study aims describe survival outcomes and clinicopathologic characteristics patients with breast cancer at our Center. METHODS A retrospective cohort treated between January 2012 December 2020 was conducted. Survival were assessed using Kaplan-Meier method. Univariate multivariate analyses performed Cox...
Desmoplastic stroma (DS) and the epithelial-to-mesenchymal transition (EMT) play a key role in pancreatic ductal adenocarcinoma (PDAC) progression. To date, however, combined expression of DS EMT markers, their association with variations survival within each clinical stage degree tumor differentiation is unknown. The purpose this study was to investigate between markers variability patients diagnosed PDAC. We examined levels alpha smooth muscle actin (α-SMA), fibronectin, vimentin,...
<h3>Background</h3> Macrophages are an immunological cell present in tumor microenvironment. with the M2 phenotype promote development through immunosuppression of antitumor immunity. Previous studies indicate that bone marrow- derived mesenchymal stem/stromal cells (BM-MSCs) have property increasing polarization macrophages.<sup>1</sup> We previously demonstrated presence MSCs cervical cancer (CeCa-MSCs), promoting inhibition CD8 T lymphocyte cytotoxicity over cells,<sup>2</sup> suggesting...
During the last two decades, three different epidemics, caused by coronaviruses, have affected humankind. The most recent, known as COVID-19, has in only five months, more than 340,000 deaths worldwide. Knowing biology of coronavirus is key, not just to face current pandemic, but prepare ourselves for future epidemics. With this mind, article focused on coronaviruses emphasizing SARS-CoV-2, agent that causes COVID-19. This a comprehensive review article, which covers topics, from and...