A5003788478- Echinoderm biology and ecology
- Marine and coastal plant biology
- Adenosine and Purinergic Signaling
- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Cervical Cancer and HPV Research
- Immunotherapy and Immune Responses
- Mesenchymal stem cell research
- Ocean Acidification Effects and Responses
- Aquaculture Nutrition and Growth
- Cephalopods and Marine Biology
- Immune Cell Function and Interaction
- Reproductive biology and impacts on aquatic species
- Protist diversity and phylogeny
- Marine Biology and Environmental Chemistry
- Cancer Cells and Metastasis
- Photoreceptor and optogenetics research
- Microtubule and mitosis dynamics
- Marine Bivalve and Aquaculture Studies
- Protein Hydrolysis and Bioactive Peptides
- Neurobiology and Insect Physiology Research
- Cancer Immunotherapy and Biomarkers
- Physiological and biochemical adaptations
- RNA Interference and Gene Delivery
- Animal Genetics and Reproduction
Mexican Social Security Institute
2016-2025
Universidad Nacional Autónoma de México
1993-2025
Universidad de Zaragoza
2009-2024
Centro Medico Nacional Siglo XXI
2013-2020
Autonomous University of Tlaxcala
2015
WinnMed
1999-2015
LA Referencia
2015
Mayo Clinic
1999-2015
Universidad Autónoma de Baja California
2008
Universidad Autónoma de Baja California Sur
2001
We introduce an intuitive particle-based model of time-symmetric quantum physics that gives a concrete description what goes on in the time between projective measurements system. The time-symmetry this means we ...Physical interpretations formulation mechanics, due to Aharonov, Bergmann, and Lebowitz are discussed terms weak values. most direct, yet somewhat naive, interpretation uses ...
1. The paper describes electrical characteristics of the egg starfish Asterias forbesii as measured with a microelectrode penetrating surface. study included effects fertilizing while latter was impaled on electrode. 2. It has been confirmed that penetration membrane cannot be indicated solely by seeming visualization at center egg. 3. A method involving use two microelectrodes is described for ascertaining One internal electrode delivers current pulse and other records time course resultant...
Bone marrow-mesenchymal stromal cells (BM-MSCs) have immunosuppressive properties and been used in cell therapies as immune regulators for the treatment of graft-versus-host disease. We previously characterized several biological MSCs from placenta (PL) umbilical cord blood (UCB), compared them to those BM-the gold standard. In present study, we BM, UCB, PL terms their against lymphoid populations enriched CD3(+) T cells. Our results confirm potential BM-MSCs, demonstrate that UCB and, a...
In recent years, immunomodulatory mechanisms of mesenchymal stem/stromal cells (MSCs) from bone marrow and other "classic" sources have been described. However, the phenotypic functional properties tumor MSCs are poorly understood. The aim this study was to analyze immunosuppressive capacity cervical cancer-derived (CeCa-MSCs) on effector T lymphocytes through purinergic pathway.We determined expression activity membrane-associated ectonucleotidases CD39 CD73 CeCa-MSCs normal tissue-derived...
Since the second half of 20th century, our knowledge about biology cancer has made extraordinary progress. Today, we understand at genomic and epigenomic levels, have identified cell that starts neoplastic transformation characterized mechanisms for invasion other tissues. This allowed novel drugs to be designed act on specific molecular targets, immune system trained manipulated increase its efficiency, ever more effective therapeutic strategies developed. Nevertheless, are still far from...
The authors have investigated the structural variations of cortical layer Psammechinus miliaris egg after fertilization or parthenogenetic activation, by means polarized light, hypertonic treatment and colchicine.They found regular cyclic birefringence layer. A first inconstant cycle appears at 15-20 minutes activation. second, more intense constant end metaphase up to telophase cleavage, or, in parthenogeneric eggs, expansion monaster.In eggs treated with solution, "spherical plasmolysis"...
Macrophages with the M2 phenotype promote tumor development through immunosuppression of antitumor immunity. We previously demonstrated presence mesenchymal stem/stromal cells (MSCs) in cervical cancer (CeCa-MSCs), suggesting an immune protective capacity tumors, but to date, their effect modulating macrophage polarization remains unknown. In this study, we compared capacities MSCs from normal cervix (NCx) and CeCa a coculture system. Our results that CeCa-MSCs, contrast NCx-MSCs,...
Abstract Background Even though two prophylactic vaccines against HPV are currently licensed, infections by the virus continue to be a major health problem mainly in developing countries. The cost of limits wide-scale application poor A promising strategy for producing affordable and efficient involves expression recombinant immunogens plants. Several genes have been expressed plants, including L1, which can self-assemble into virus-like particles. plant-based, dual prophylactic/therapeutic...
Fertilized, mechanically demembranated, eggs of the sea urchins Lytechinus pictus and variegatus can be re-fertilized when heavily re-inseminated at a half-hour or more (17° to 22° C.) after initial fertilization. The re-fertilization occurs readily earlier second insemination is performed. reinseminated tend become polyspermic. Concentrations sperm that give 100 per cent do not cause any significant polyspermy used as first inseminate on normal unfertilized eggs. results show only...
The presence of TGF-β in the tumor microenvironment cervical cancer (CC) is important for progression. In this study, we analyzed effect on expression ectonucleotidases CD39 and CD73, which are involved generation adenosine (Ado), CC cells extracellular vesicles (EVs) secreted by these cells. Treatment HeLa CaSki 72 h with recombinant human increased CD73 20 30% 40 100%, respectively. addition SB505124, an inhibitor TGF-β1 receptor, or GW4869, exosome formation release, reduced release both...
DNA hypermethylation and histone deacetylation are epigenetic events that contribute to the absence or downregulated expression of different components tumor recognition complex. These affect processing presentation antigenic peptides CTLs by HLA class-I molecules. In this work evaluated effect hypomethylating agent hydralazine deacetylase inhibitor valproic acid, on molecules antigen-specific immune cervical cancer cells. Cell lines C33A (HPV-), CaSki (HPV-16+) MS751 (HPV-18+) were treated...
The objective of this study was to evaluate Sargassum meal as feed for sheep through the measures in vivo digestibility, dry matter degradability, pH, ammonia and volatile fatty acids rumen. algae used experiment were collected at end spring, when they are more abundant, bigger, have completed their reproductive cycle. Four tons (wet weigth) manually from intertidal zone La Paz bay, Baja California Sur, Mexico. These sun-dried ground a hammer mill obtain meal. fistulated Pelibuey sheep, fed...