A5015476176- Essential Oils and Antimicrobial Activity
- Oral microbiology and periodontitis research
- Infective Endocarditis Diagnosis and Management
- Antifungal resistance and susceptibility
- Phytochemistry Medicinal Plant Applications
- Bee Products Chemical Analysis
- Streptococcal Infections and Treatments
- Plant Pathogens and Fungal Diseases
- Antimicrobial Peptides and Activities
- Endodontics and Root Canal Treatments
- Phytochemistry and Biological Activities
- Oral Health Pathology and Treatment
- Antimicrobial agents and applications
- Phytochemicals and Medicinal Plants
- Dental Health and Care Utilization
- Bacterial biofilms and quorum sensing
- Oral and gingival health research
- Dental materials and restorations
- Animal testing and alternatives
- Dental Erosion and Treatment
- Ocular Infections and Treatments
- Dental Research and COVID-19
- Ethnobotanical and Medicinal Plants Studies
- Youth, Drugs, and Violence
- Photodynamic Therapy Research Studies
Universidade Estadual de Campinas (UNICAMP)
2012-2023
University of Florida
2017-2022
Florida College
2017-2022
University of Rochester Medical Center
2015-2016
Universidade Federal da Paraíba
2010-2012
As a major etiological agent of human dental caries,
Oral candidiasis is an opportunistic fungal infection of the oral cavity with increasingly worldwide prevalence and incidence rates. Novel specifically-targeted strategies to manage this ailment have been proposed using essential oils (EO) known antifungal properties. In study, we aim investigate activity mode action EO from Coriandrum sativum L. (coriander) leaves on Candida spp. addition, detected molecular targets affected in whole-genome expression human cells. The phytochemical profile...
Objective: The aim of the present study was to encapsulate vancomycin in different liposomal formulations and compare vitro antimicrobial activity against Staphylococcus aureus biofilms. Methods: Large unilamellar vesicles conventional (LUV VAN), fusogenic (LUVfuso cationic (LUVcat VAN) liposomes encapsulating VAN were characterized terms size, polydispersity index, zeta potential, morphology, encapsulation efficiency (%EE) release kinetics. tested for their Minimum Inhibitory Concentration...
Staphylococcus aureus infections have contributed to the global healthcare burden, particularly with regard hospital-acquired meticillin-resistant S. (MRSA) infections.This study describes antibacterial activity of diacetylcurcumin (DAC) against meticillin-susceptible aureus/MRSA biofilm formation, survival, metabolic and structure; its ability prevent bacterial adhesion human cells; toxicity in Galleria mellonella larvae.DAC showed excellent activity, MIC ranging between 17.3 34.6 µmol l-1,...
The objective of this study was to investigate the effectiveness (+)-β-pinene inhibition on Candida spp. growth, aiming at elucidation mechanism action; determine fungal cell enzyme binding activity (through molecular docking simulations) and its effects biofilm reduction.Candida strains (n=25) from referenced clinical origins, either susceptible or resistant standard antifungals, were tested for determination Minimum Inhibitory Concentration (MIC); Fungicidal (MFC); microbial death curves...
The essential oils (EO) and bioactive fractions (BF) from Aloysia gratissima, Baccharis dracunculifolia, Coriandrum sativum, Cyperus articulatus, Lippia sidoides were proven to have strong antimicrobial activity on planktonic microorganisms; however, little is known about their effects the morphology or viability of oral biofilms. Previously, we determined EO/fractions with best against Streptococcus mutans Candida spp. In this report, used a confocal analysis investigate effect these EO BF...
Context The emergence of resistant pathogens and toxicity antifungals have encouraged an active search for novel candidates to manage Candida biofilms. Objective In this study, the little known species Sideroxylon obtusifolium T.D. Penn (Sapotacea) Syzygium cumini (L.) Skeels (Myrtaceae), from Caatinga biome in Brazil were chemically characterized explored their antifungal potential against C. albicans. Materials methods We determined effects hydroalcoholic extracts/fractions upon fungal...
In S. mutans, the expression of surface glycoprotein Cnm mediates binding to extracellular matrix proteins, endothelial cell invasion and virulence in Galleria mellonella invertebrate model. To further characterize as a factor, cnm gene from mutans strain OMZ175 was expressed non-pathogenic Lactococcus lactis NZ9800 using nisin-inducible system. Despite absence machinery necessary for glycosylation, Western blot immunofluorescence microscopy analyses demonstrated that effectively...
Hypertension is a systemic condition with high morbidity and mortality rates worldwide, which poses an increased risk for cardiovascular diseases. In this study, we demonstrated the antioxidant vasodilator activity of Ugni molinae Turcz. (Murtilla) fruit, berry native to Chile proposed models explain its modulatory mechanism in hypotensive response. Murtilla fruits were cultivated germplasm bank submitted chemical biological analyses. The phenolic compounds gallic acid, Catechin,...