A5003695862- Asymmetric Hydrogenation and Catalysis
- Carbon dioxide utilization in catalysis
- Nanomaterials for catalytic reactions
- Organometallic Complex Synthesis and Catalysis
- Porphyrin and Phthalocyanine Chemistry
- Catalytic Cross-Coupling Reactions
- biodegradable polymer synthesis and properties
- Chemistry and Chemical Engineering
- Innovative Microfluidic and Catalytic Techniques Innovation
- Chemical Synthesis and Analysis
- Catalysis and Oxidation Reactions
- Catalysis for Biomass Conversion
- Synthesis and Biological Evaluation
- Mesoporous Materials and Catalysis
- Catalysis and Hydrodesulfurization Studies
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Photodynamic Therapy Research Studies
- Catalytic Processes in Materials Science
- Chemical Synthesis and Reactions
- Click Chemistry and Applications
- Advanced Polymer Synthesis and Characterization
- Catalytic Alkyne Reactions
- Zeolite Catalysis and Synthesis
- Antimicrobial agents and applications
University of Coimbra
2015-2024
Laboratoire de Réactivité de Surface
2001
Sorbonne Université
2001
Centre National de la Recherche Scientifique
2001
Chimie ParisTech
2000
Abstract Catalytic hydroformylation is an important reaction, widely studied by academics and applied in the chemical industry, it a paradigmatic example of reaction that aligned with most Green Chemistry principles. In last years, global requirement for more sustainable processes has boosted development active, selective, reusable catalysts. this review, we highlight recent advances regarding creation expansion catalysts sequential use as central reaction. The relevant strategies...
Abstract An active and selective dual catalytic system to promote domino hydroformylation–reduction reactions is described. Apart from terminal, di‐ trisubstituted olefins, for the first time less internal C−C double bond of tetrasubstituted alkenes can also be utilized. As an example, 2,3‐dimethylbut‐2‐ene converted into corresponding n ‐alcohol with high yield (90 %) as well regio‐ chemoselectivity (>97 %). Key this development use a combination Rh complexes bulky monophosphite ligands...
Nowadays, society’s widespread consumption of pharmaceutical drugs and the consequent accumulation such compounds or their metabolites in effluents requires development efficient strategies systems that lead to effective degradation. This can be done through oxidative processes, which tetrapyrrolic macrocycles (porphyrins, phthalocyanines) deserve special attention since they are among most promising degradation catalysts. paper presents a review literature over past ten years on major...
The intrinsic challenge of large molecules to cross the cell membrane and reach intracellular targets is a major obstacle for development new medicines. We report how rotation along single C–C bond, between atropisomers drug in clinical trials, improves uptake therapeutic efficacy. redaporfin (a fluorinated sulfonamide bacteriochlorin photosensitizer 1135 Da) are separable display orders magnitude differences photodynamic efficacy that directly related their differential cellular uptake....
Herein we describe the design of natural curcumin ester and ether derivatives their application as potential bioplasticizers, to prepare photosensitive phthalate-free PVC-based materials. The preparation films incorporating several loadings newly synthesized along with standard solid-state characterization is also described. Remarkably, plasticizing effect in PVC material was found be similar that observed previous PVC–phthalate Finally, studies applying these new materials photoinactivation...
The quest for active, yet “green” non-toxic catalysts is a continuous challenge. In this work, covalently linked hybrid porphyrin–nanodiamonds were prepared via ipso nitro substitution reaction and characterized by X-ray photoelectron spectroscopy (XPS), fluorescence spectroscopy, infrared (IR) thermogravimetry-differential scanning calorimetry (TG-DSC). amine-functionalized nanodiamonds (ND@NH2) 2-nitro-5,10,15,20-tetra(4-trifluoromethylphenyl)porphyrin to (ND@βNH-TPPpCF3) tested using...
Over the last centuries, influenza virus has been cause of one deadliest and most concerning respiratory tract infections. Besides being annually responsible for thousands deaths worldwide, it's capable originating pandemics that can affect millions people, like COVID-19. Photodynamic inactivation (PDI) is an emerging alternative solution treatment control viral infections several studies have already shown it be efficient against viruses. Herein we give a brief overview key biological...
Two heterogeneous catalysts, MNP@SiO2-N-Xantphos/Rh(I) and MNP@SiO2-NH-C-scorpionate/Fe(II), were prepared by reaction of chloro-functionalized MNP@SiO2 with N-Xantphos amino-functionalized iron(II)/C-allyl-scorpionate through nucleophilic substitution hydroaminomethylation reactions, respectively. All catalysts characterized using standard spectroscopic means, transmission electron microscopy (TEM), thermogravimetry (TG), inductively coupled plasma optical emission spectrometry (ICP-OES)....
Four stereoisomeric monoether derivatives, based on axially chiral (R)- or (S)-BINOL bearing a (+)- (-)-neomenthyloxy group were synthesised and fully characterised by NMR spectroscopy X-ray crystallography. The respective tris-monophosphites thereof prepared characterised. coordination ability of the new bulky phosphites with Rh(CO)2(acac), was attested 31P NMR, which presented doublet in range δ = 120 ppm, 1J(103Rh-31P) coupling constant 290 Hz. tris-binaphthyl phosphite ligands further...
The immobilization of Rh/phosphorus complexes in MCM-41 was performed using two different methodologies. first synthetic strategy based on the covalent attachment a new binaphthyl-based phosphoramidite ligand through trimethoxysilyl linkage, followed by its complexation with rhodium(I) precursor Rh(CO)2(acac). resulting heterogeneized Rh(I)/phosphoramidite complex characterized FT-IR, N2 adsorption and TG-DSC techniques, which indicated effective bonding to mesoporous material. A second...
Neuropeptide Y (NPY) is one of the most abundant peptides in central nervous system mammals and involved several physiological processes through NPY Y1, Y2, Y4 Y5 receptors. Of those, Y2 receptor has particular relevance for its autoreceptor role inhibiting release other neurotransmitters involvement relevant mechanisms such as feeding behaviour, cognitive processes, emotion regulation, circadian rhythms disorders epilepsy cancer. PET imaging can provide a valuable platform to understand...
We report an efficient continuous flow process, integrating a custom-designed gas input control system coupled with tubular reactor, for Pd-catalysed aminocarbonylation, which leads to the multigram synthesis of biologically relevant carboxamides.
This work describes an innovative catalytic process for aqueous trimethoprim degradation, using a fixed-bed continuous flow reactor packed with manganese(III)
Abstract Background Biofilm in medical devices occurs with bacterial adherence through virulence factors by a favorable environment for their proliferation. The transfer of microbial cells from biofilm endotracheal tube to lungs increases the chances developing severe infections. This study aimed optimize antimicrobial photodynamic therapy (PDT) applying curcumin-functionalized an artificial respiratory system avoiding and dispersion system, adding mechanical ventilator. Methods model was...