Irene Aícua‐Rapún

ORCID: 0000-0002-1096-2284
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About
Contact & Profiles
Research Areas
  • Pharmacological Effects and Toxicity Studies
  • Epilepsy research and treatment
  • Neuroscience and Neuropharmacology Research
  • Drug Transport and Resistance Mechanisms
  • Migraine and Headache Studies
  • Spinal Dysraphism and Malformations
  • Body Image and Dysmorphia Studies
  • Cardiovascular Syncope and Autonomic Disorders
  • Anesthesia and Sedative Agents
  • Airway Management and Intubation Techniques
  • Fetal and Pediatric Neurological Disorders
  • Teratomas and Epidermoid Cysts
  • Psychosomatic Disorders and Their Treatments
  • Sympathectomy and Hyperhidrosis Treatments
  • Trauma Management and Diagnosis
  • Respiratory Support and Mechanisms

University Hospital of Lausanne
2018-2025

University of Lausanne
2018-2022

Spitalzentrum Centre hospitalier Biel- Bienne
2022

Hospital Universitario de Burgos
2016-2017

OnabotulinumtoxinA (OnabotA) is effective in Chronic Migraine (CM) during first year of treatment and longer. In real clinical setting, CM patients with acute Medication Overuse (MO) or concurrently receiving oral preventatives are treated OnabotA. We aim to assess evolution beyond on Data were retrospectively collected three headache units. analyzed cases who had received at least five sessions OnabotA according PREEMPT protocol. continued therapy when a reduction number days 30% was...

10.1186/s10194-016-0702-1 article EN cc-by The Journal of Headache and Pain 2016-12-01

Therapeutic drug monitoring (TDM) of antiepileptic drugs (AEDs) is widely established for older generation AEDs, whereas there limited evidence about newer AEDs. Our aim to assess the benefit TDM AEDs in epilepsy.We performed a randomized, controlled trial comparing systematic with rescue lamotrigine, levetiracetam, oxcarbazepine, topiramate, brivaracetam, zonisamide, or pregabalin. Participants were adults epilepsy, whom treatment was initiated needed adjustment. In arm, AED plasma levels...

10.1002/ana.25641 article EN Annals of Neurology 2019-11-12

Aim To investigate the relationship between primary headache types and accomplished or attempted suicide in countries from all world regions. Methods Data were obtained using a questionnaire about due to face-to-face interview with 203 physicians expertise headaches. They came 48 countries, continents. Results Primary headaches cause one per 1,000,000 population each year (1% of rate causes). Cluster migraines account for 70-80% them. Suicide attempts are 10 times more frequent than...

10.1177/0333102417714477 article EN Cephalalgia 2017-06-05

Objectives Contrary to older antiseizure medications (ASM), correlation between plasma levels and seizure freedom is not well defined for newer generation ASM. We assessed correlations efficacy ASM in patients with epilepsy. Materials Methods Plasma medication were measured over two years consecutive taking lamotrigine, levetiracetam, oxcarbazepine, topiramate, zonisamide, lacosamide, perampanel or pregabalin. Seizure was as three times the longest inter-seizure pre-treatment interval, at...

10.1111/ane.13450 article EN Acta Neurologica Scandinavica 2021-05-05

To communicate a complication of prone-position ventilation.Case history.Case report.Clinical information from medical record.This is very infrequent cause dysphagia following ventilation.

10.1097/ccm.0000000000002411 article EN Critical Care Medicine 2017-04-19

The benefit of therapeutic drug monitoring (TDM) newer generation antiseizure medications (ASM) has been little studied. A recent randomized study suggested that TDM at each medical visit did not bring a significant benefit, but the investigate in cases treatment failure. Accordingly, we realized post hoc analysis this trial.We analyzed 282 TDMs 136 patients. We compared performed visits after failure versus without failure, reporting proportion levels out range and prescriber's adherence to...

10.1016/j.seizure.2021.11.022 article EN cc-by-nc-nd Seizure 2021-11-28

This clinical vignette describes the interdisciplinary diagnostic approach to a patient with cystic brain lesions. The scope of this case is develop reasoning skills trainees in neuroscience, taking into account alternative diagnoses and unusual presentations.

10.1177/2514183x19866098 article EN cc-by Clinical and Translational Neuroscience 2019-07-01
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