- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Sexual function and dysfunction studies
- Prostate Cancer Diagnosis and Treatment
- Urological Disorders and Treatments
- Anesthesia and Pain Management
- Pain Management and Treatment
- Kidney Stones and Urolithiasis Treatments
- Anorectal Disease Treatments and Outcomes
- Pain Mechanisms and Treatments
- Tissue Engineering and Regenerative Medicine
- Urinary Tract Infections Management
- Ureteral procedures and complications
- Spine and Intervertebral Disc Pathology
- Pediatric Urology and Nephrology Studies
- Spinal Dysraphism and Malformations
- Botulinum Toxin and Related Neurological Disorders
- Hormonal and reproductive studies
- Neurological disorders and treatments
- Peripheral Nerve Disorders
- Spinal Cord Injury Research
- Nitric Oxide and Endothelin Effects
- Anesthesia and Neurotoxicity Research
- Neuroscience of respiration and sleep
- Sexuality, Behavior, and Technology
University of Toronto
2015-2024
Toronto Western Hospital
2014-2023
University Health Network
2011-2023
Cleveland Clinic Lerner College of Medicine
2018
Toronto Rehabilitation Institute
2015-2016
Western Research Institute
2011-2013
Hospital General de México
2012
Queen Square Radiosurgery Centre
2012
Universidad Anáhuac
2012
Kobe Medical Center
2012
This 5-year, prospective, multicenter trial evaluated the long-term safety and efficacy of sacral neuromodulation in patients with refractory urge incontinence, urgency frequency retention.A total 17 centers worldwide enrolled 163 (87% female). Following test stimulation 11 declined implantation 152 underwent using InterStim. Of those treated 96 (63.2%) had 25 (16.4%) 31 (20.4%) retention. Voiding diaries were collected annually for 5 years. Clinical success was defined as 50% or greater...
No AccessJournal of UrologyClinical Urology: Original Articles1 Aug 1999SACRAL NERVE STIMULATION FOR TREATMENT OF REFRACTORY URINARY URGE INCONTINENCE RICHARD A. SCHMIDT, UDO JONAS, KIMBERLY OLESON, RUUD JANKNEGT, MAGDY M. HASSOUNA, STEVEN W. SIEGEL, and PHILIP E.V. van KERREBROECK SCHMIDTRICHARD SCHMIDT , JONASUDO JONAS OLESONKIMBERLY OLESON JANKNEGTRUUD JANKNEGT HASSOUNAMAGDY HASSOUNA SIEGELSTEVEN SIEGEL KERREBROECKPHILIP View All Author...
Neuromodulation of sacral nerves has shown promising results in correcting voiding dysfunction. We report the a multicenter trial designed to assess efficacy nerve neuromodulation patients presenting with refractory urinary urgency-frequency.A total 51 from 12 centers underwent baseline assessment, including detailed diary, urodynamic evaluation and percutaneous test stimulation at S3 and/or S4. All enrolled study had undergone prior conventional treatment, such as pharmacotherapy,...
No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles1 Jan 2001EFFICACY OF SACRAL NERVE STIMULATION FOR URINARY RETENTION: RESULTS 18 MONTHS AFTER IMPLANTATION U. JONAS, C.J. FOWLER, M.B. CHANCELLOR, M.M. ELHILALI, M. FALL, J.B. GAJEWSKI, V. GRÜNEWALD, HASSOUNA, U.v.d. HOMBERGH, R. JANKNEGT, P.E.V. van KERREBROECK, A.A.B. LYLCKLAMA à NIJEHOLT, S.W. SIEGEL, and R.A. SCHMIDT JONASU. JONAS , FOWLERC.J. FOWLER CHANCELLORM.B. CHANCELLOR ELHILALIM.M. ELHILALI FALLM. FALL GAJEWSKIJ.B....
Sacral foramina implants have been recognized recently as a method for treatment of refractory urinary urge incontinence. We study the outcome procedure with in-depth analysis results 18 implanted cases.Patients incontinence were subjected to percutaneous nerve evaluation S3 roots temporary screening test determine response neuromodulation. Satisfactory responders permanent sacral root neuroprosthesis. The design included comprehensive voiding diaries 4 consecutive days twice baseline, 1...
Sacral neuromodulation (SNM) is an accepted therapy for a variety of conditions. However, despite over 20 years experience, it remains specialized procedure with number subtleties. Here we present the recommendations issued from International Continence Society (ICS) SNM Consensus Panel.Under auspices ICS, eight urologists, three colorectal surgeons and two urogynecologists, covering wide breadth geographic specialty interest representation, met in January 2017 to discuss best practices...
Sacral root neuromodulation is becoming a superior alternative to the standard treatment of idiopathic nonobstructive urinary retention. We report results in 20 successive patients who underwent sacral foramen implantation restore bladder function.After an initial, thorough baseline assessment 19.43 55.66 years old with retention percutaneous nerve evaluation. Response was assessed by detailed voiding diary. Responders S3 implant, and were followed 1, 3 6 months postoperatively, every...
No AccessJournal of Urology1 Jan 1993The Effect Diabetes on Sexual Behavior and Reproductive Tract Function in Male Rats Ayman A. Hassan, Magdy M. Hassouna, Teruko Taketo, Claude Gagnon, Mostafa Elhilali HassanAyman Hassan , HassounaMagdy Hassouna TaketoTeruko Taketo GagnonClaude Gagnon ElhilaliMostafa View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)36028-7AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail...
No AccessJournal of Urology1 Dec 1994Neural Stimulation for Chronic Voiding Dysfunctions Ahmed A. Elabbady, Magdy M. Hassouna, and Mostafa Elhilali ElabbadyAhmed Elabbady , HassounaMagdy Hassouna ElhilaliMostafa View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)32312-1AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Neural stimulation the sacral nerve roots could become an acceptable promising modality in...
Abstract Aims This study was sought to evaluate the efficacy and durability of sacral neuromodulation in treatment bladder pain syndrome (BPS) patients. Methods A retrospective chart review performed patients who had unilateral nerve stimulator (InterStim®) for refractory BPS between June 2002 December 2004. Patients were qualified permanent implantation by showing ≥50% improvement their voiding symptoms 1‐week post‐percutaneous evaluation (PNE). Voiding diary completed at pre‐implantation,...
OBJECTIVE To evaluate the urodynamic data before and 6 months after implantation of sacral neuromodulation (SNM, an established treatment for voiding dysfunction, including refractory urge urinary incontinence, UI) to assess correlation between clinical efficacy in patients with UI. PATIENTS AND METHODS In all, 111 a >50% reduction UI symptoms during percutaneous nerve evaluation test qualified surgical SNM. Patients were categorized two subgroups, i.e. those or without confirmed detrusor...
To determine whether sacral root neuro-modulation (a promising therapeutic modality in patients with refractory voiding and storage problems) has its effect through the blockade of C-afferent fibres that form afferent limb a pathological reflex arc responsible for dysfunction bladder storage.The study comprised 39 female Sprague Dawley rats divided into three equal groups: normal controls (group 1); spinally transected at T10 2); electrically stimulated bilaterally S1 6 h daily 3). Three...
Pelvic disorders affecting both male and female patients are major areas of concern for clinicians in cases where pharmacotherapy behavioral therapy not effective. In such cases, pelvic neuromodulation has become an alternative that could relieve chronic pain enhance the quality life. The goal this paper was to present a summary current therapeutic applications various techniques their efficacy treating with range illnesses. Based on available literature, review assessed validity...
Neuromodulation of the sacral nerve roots is effective to treat various voiding dysfunctions, but underlying mechanism neuromodulation not known. The objective this study evaluate whether inhibition afferent c-fiber activity root neuromodulation.Twenty-nine female Sprague-Dawley rats weighing 220 250 gm. were divided into 4 groups: normal control (normal without any procedure; n = 5), sham with saline (spinalized at T9 bladder instillation; 7), acetic acid 8) and stimulation group...
Sacral neuromodulation (SNM) has become an established therapy for voiding dysfunction. Additional benefits, such as improved bowel functions and bladder pain, have been reported. Improvement in female sexual function after SNM treatment suggested; however, reports examining the effects of on are scarce. We evaluate its impact quality life analyze any correlation.Data were collected from January 2010 to May 2012 all patients who underwent InterStim (Medtronic, Minneapolis, MN) at a single...
Study Type – Aetiology (case control) Level of Evidence 3c What's known on the subject? and What does study add? Neurogenic detrusor overactivity (NDO) autonomic dysreflexia (AD) are common outcomes following spinal cord injury (SCI). In this study, we showed that onabotulinumtoxinA controlled NDO AD in rats with T4‐SCI, also provided a mechanism for control AS. OBJECTIVE To assess significance (onabotA) intravesical administration blocking response induced by cystometrogram (CMG) after T4...