A5064907738- Retinal Imaging and Analysis
- Liver Disease Diagnosis and Treatment
- Hepatitis Viruses Studies and Epidemiology
- Monoclonal and Polyclonal Antibodies Research
- Retinal Diseases and Treatments
- Child Nutrition and Feeding Issues
- Functional Brain Connectivity Studies
- MicroRNA in disease regulation
- Extracellular vesicles in disease
- Intestinal Malrotation and Obstruction Disorders
- Infant Nutrition and Health
- Immunotherapy and Immune Responses
- Cancer therapeutics and mechanisms
- Hepatitis B Virus Studies
- Cell Adhesion Molecules Research
- Viral Infections and Vectors
- Blood Coagulation and Thrombosis Mechanisms
- Hepatitis C virus research
- Ophthalmology and Visual Impairment Studies
- Phosphodiesterase function and regulation
- EEG and Brain-Computer Interfaces
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Complex Systems and Time Series Analysis
- Circular RNAs in diseases
Southern Medical University
2025
Guangdong Provincial People's Hospital
2025
Linyi People's Hospital
2025
Guangdong Academy of Medical Sciences
2025
Shanxi University
2024
Fifth Affiliated Hospital of Zhengzhou University
2024
Shandong First Medical University
2024
University of Science and Technology of China
2023
First Affiliated Hospital of Bengbu Medical College
2023
Zhejiang Academy of Medical Sciences
2014
Urokinase-type plasminogen activator receptors (uPARs), up-regulated during tumor progression, associate with β1 integrins, localizing urokinase to sites of cell attachment. Binding uPAR the β-propeller α3β1 empowers vitronectin adhesion by this integrin. How modifies other integrins remains unknown. Using recombinant proteins, we found directly binds α5β1 and rather than blocking, renders fibronectin (Fn) binding Arg-Gly-Asp (RGD) resistant. This resulted from RGD-independent α5β1–uPAR Fn...
Interferon regulatory factor 2 (IRF2) participates in the differentiation of immune T cells. Bone marrow mesenchymal stem cell (BM-MSC)-derived exosomes can secret mRNA, miRNAs, and proteins to regulate tumor microenvironment. The present study focused on miRNA/IRF2 axis regulating Th1/Th2 ratio apoptosis acute myeloid leukemia (AML). flow cytometry analysis was performed examine AML vivo vitro. contents γ (IFN-γ) Interleukin-4 (IL-4) were measured using enzyme-linked immunosorbent assay....
Background: Little is known about the prospective relationship between visual acuity (VA) and atherosclerotic cardiovascular disease (ASCVD) events extent to which this association mediated via potential mediators. This study aims investigate VA ASCVD events, including mediation effects of factors. Methods: A was conducted using data from 110,522 participants in UK Biobank, all whom had baseline measurements collected 2006 2010. assessed logarithm minimum angle resolution (logMAR) chart,...
Abstract Post-stroke apathy (PSA) is a highly heterogeneous disorder that affects approximately 30% of stroke survivors. Nevertheless, comprehensive understanding regarding neurobiological mechanisms the heterogeneity PSA lacking. We hypothesized effort-based reward decision network (ERDN) may play critical role in heterogeneity. Therefore, we prospectively recruited 190 patients with acute ischemic and 50 demographically matched healthy controls. Sparse canonical correlation analysis (SCCA)...
Objective To analyze the epidemic features of hepatitis A in mainland China during 2004 and 2012 for effective prevention control.Methods The incidence was analyzed by using Excel 2007 software.The disease situation including trend time,regional population distribution were described.Results During 2012,the number cases substantially decreased year year,and totally 503 817 reported,including 202 deaths(0.04％).The yearly fluctuated between 1.78/100 000 7.34/100 with an average rate 4.00/100...
To investigate the structure and function of N-terminal region (NTR) death receptor 5 (DR5).A series deletions DR5 extracellular domain (DR5-ECD) proteins were expressed in E.coli. purified by affinity chromatography. The binding ability these deletant to AD5-10, a mouse anti-human monoclonal antibody, was evaluated immunoblotting ELISA.Recombinant DR5-ECD containing NTR recognized bound while other without failed interact with AD5-10.There is an AD5-10 targeting site DR5, which may play...