A5023468916- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Crystal structures of chemical compounds
- Synthesis and biological activity
- Crystal Structures and Properties
- Crystallography and molecular interactions
- Metal complexes synthesis and properties
- Advanced Condensed Matter Physics
- Magnetism in coordination complexes
- Synthesis of heterocyclic compounds
- Synthesis and Characterization of Heterocyclic Compounds
- Metal-Organic Frameworks: Synthesis and Applications
- Solid-state spectroscopy and crystallography
- Chemical Synthesis and Characterization
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Organometallic Compounds Synthesis and Characterization
- Nuclear materials and radiation effects
- Click Chemistry and Applications
- Physics of Superconductivity and Magnetism
- Multicomponent Synthesis of Heterocycles
- Lanthanide and Transition Metal Complexes
- Inorganic and Organometallic Chemistry
- Nonlinear Optical Materials Research
- Synthesis and Biological Evaluation
- Bioactive Compounds and Antitumor Agents
Université Sultan Moulay Slimane
2015-2024
Cadi Ayyad University
2002-2008
Czech Academy of Sciences, Institute of Physics
2006
École Nationale Supérieure de Chimie de Lille
1998-2006
Centre National de la Recherche Scientifique
1998-2006
Laboratoire de Cristallographie et Sciences des Matériaux
2004
Chouaib Doukkali University
1999-2000
Laboratoire de Chimie de Coordination
2000
Université d'Artois
2000
Abstract A new 1,2,3‐triazole sesquiterpenic named (4aR,5aS,7aR,10aR,10bR)‐10‐benzyl‐5,5‐dichloro‐1,1,4a,7a‐tetramethyl‐1,2,3,4,4a,5,7a,10,10a,10b decahydrocyclopropa[2′,3′]cyclohepta [1′,2′:3,4]benzo[1,2‐d][1,2,3]triazol‐7(6H)‐one was synthesized by a dipolar cycloaddition 1,3 between benzyl azide and α,β‐unsaturated sesquiterpene ketone catalyzed titanium tetrachloride TiCl 4 . It obtained with good yield characterized using single‐crystal X‐ray diffraction technique, infra red (IR)...
The BiCu(2)(P(1-x)V(x))O(6) system shows the appearance of various phenomena that progressively change as a function average (P/V)O(4) groups size. Then, from x = 0 to approximately 0.7, solid solution exists with respect basic orthorhombic unit cell BiCu(2)PO(6). For greater values (0.7 < <0.96), structural modulations incommensurate q vector slightly versus appear. 4-D treatment single-crystal XRD data modulated phase corresponding 0.87 at 100 K (orthorhombic, 12.379(3)Angstrom, b...
Background: This study aimed to develop novel isoxazoline-1,3,4-thiadiazole hybrids from (S)-verbenone for potential anticancer treatment, particularly focusing on cytotoxic and apoptotic effects in hormone-sensitive MCF-7 triple-negative MDA-MB-231 breast cancer cells. Methods & results: was used synthesize through 1,3-dipolar cycloaddition, followed by thorough characterization. The compounds were screened across cell lines, showing significant effects. Compound 8b notably induced...
Treatment of thiosemicarbazones prepared from sesquiterpenes with ethyl 2-bromoacetate in the presence sodium acetate afforded corresponding thiazolidin-4-ones. The structures all newly synthesized compounds were established by considering spectral and single-crystal X-ray diffraction data. title compound, 2-((Z)-2-{(Z)-[(1aR,5aR,9aS)-1,1-dichloro-1a,5,5,7-tetramethyl-1a,2,3,4,5,5a,8,9-octahydro-1H-benzo[a]cyclopropa[b][7]annulen-8-ylidene]hydrazono}-4-oxothiazolidin-3-yl)acetate,...
A series of novel 2-iminothiazolidin-4-one analogs have been synthesized from limonaketone, and structurally characterized by HR-MS, 1 H-NMR 13 C-NMR spectroscopy techniques, the structure compound 4 was elucidated XRD. The newly products were biologically evaluated in vitro for their cytotoxic activity against human cancer cell lines HT-1080, A549, MCF-7. Thiazolidinones 9 10 most active compounds HT-1080 (IC50 =15.85±1.75 16.13±1.55 μM, respectively). apoptosis induction derivatives...
A novel pyrazolo-enaminones, bipyrazoles and bipyrazolopyridines from 1-(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)butane-1,3-dione 4-methyl-2-phenyl-2H-pyrazolo[3,4-b]pyridine-3,6(3aH,7H)-dione have been synthesized by assisted heating with microwave radiation without any catalyst. The pyridine pyrazole ring formation has developed easily accessible enamino keto esters formylation followed intramolecular cyclization. general applicability for the synthesis of important pyrazolo-pyridines...
The magnetic structures of the two bismuth oxy-phosphate compounds BiMPO5 (M2+ = Ni2+, Co2+) have been determined by neutron powder diffraction using group theory analysis as a preliminary tool. Both adopt monoclinic crystal structure (S.G. P 21/n, 7.1642(2) Å, b 11.2038(3) c 5.1740(2) Å and β 107.296(2)° for Ni2+ 7.2441(1) 11.2828(1) 5.2258(1) 107.841(1)° Co2+). refinement below TN 17.5 15 K, respectively, both show that is characterized propagation vector k (−1/2, 0, 1/2), with components...
Abstract In this paper, a new diastereomerically pure isoxazolines were efficiently prepared from (S)‐verbenone, the procedure involves regioselective and diastereoselective 1,3‐dipolar cycloaddition of nitrile oxides on monoterpene's enone. The structures newly obtained cycloadducts confirmed by analytical spectral studies (HRMS, 1 H NMR, 13 C NMR). relative stereochemistry isoxazoline compounds 3a, 3c , 3d x‐ray single crystal analysis. Hirshfeld surface analysis two‐dimensional...