A5039673484- Genetic factors in colorectal cancer
- BRCA gene mutations in cancer
- DNA Repair Mechanisms
- Ovarian cancer diagnosis and treatment
- Global Cancer Incidence and Screening
- Economic and Financial Impacts of Cancer
- Venous Thromboembolism Diagnosis and Management
- Pancreatic and Hepatic Oncology Research
- Systemic Sclerosis and Related Diseases
- Adrenal and Paraganglionic Tumors
- Diabetes Treatment and Management
- COVID-19 and healthcare impacts
- Pancreatitis Pathology and Treatment
- Systemic Lupus Erythematosus Research
- Hormonal Regulation and Hypertension
- Cancer, Hypoxia, and Metabolism
Siriraj Hospital
2023-2024
Mahidol University
2023-2024
Chiang Mai University
2023
ORCID
2023
Weatherford College
2023
Abstract Multi-gene panel testing has led to the detection of pathogenic/likely pathogenic (P/LP) variants in many cancer susceptibility genes patients with breast-ovarian spectrum. However, clinical and genomic data Asian populations, including Thai patients, was underrepresented, significance multi-gene Thailand remains undetermined. In this study, we collected genetic from 4567 hereditary (HBOC) spectrum who underwent testing. Six hundred ten individuals (13.4%) had germline P/LP...
Despite the conflicting data, positivity of antiphospholipid antibodies (aPL) in cancer patients may be associated with an increased risk thrombosis.To identify prevalence and impact aPL on venous thromboembolic events (VTE) arterial thrombosis (ATE) ambulatory patients.In this single-center, prospective cohort study, we enrolled newly diagnosed receiving chemotherapy. Non-cancer controls were age- sex-matched. Participants evaluated for aPL. Primary outcomes composite outcome VTE or ATE...
Lynch syndrome is an autosomal dominant cancer predisposition with pathogenic variants in mismatch repair (MMR) genes, including MLH1, MSH2, MSH6, PMS2, or a terminal deletion of EPCAM gene. The spectrum associated LS has been reported worldwide, colorectal (CRC), endometrial cancer, and others. However, the clinical genomic data on Thailand was limited. Therefore, we aimed to establish database patients germline mutations MMR genes Thai population.
124 Background: Literature review has found profound disparities in clinical outcomes, for patient with ovarian cancer. Metastasis is the primary cause of cancer morbidity and mortality. However, data on metastasis risks hospitalized individuals still limited. Therefore, we aim to assess association between metastatic racial differences using large database analysis. Methods: We analyzed 2020 U.S. National Inpatient Sample (NIS) explore patients who have as diagnosis. Additionally,...
16 Background: Breast cancer is the most frequently diagnosed and leading cause of death in females worldwide. Recent data showed detrimental effects COVID-19 infection on other neoplasm conditions, causing increased mortality rates complications. However, limited information exists specific impacts patients hospitalized for breast cancer, as well racial impact differences. Methods: We analyzed 2020 U.S. National Inpatient Sample (NIS) to investigate cases primarily admitted due cancers....
81 Background: Recent data suggest an association between cardiovascular disease burden and biliary cancer patients. However, the outcomes of hospitalized patients for biliary-pancreatic malignancy with concurrent acute decompensated heart failure (ADHF) are not well understood. Therefore, our objective is to assess impact ADHF on malignancy. Methods: We used 2020 U.S. National Inpatient Sample (NIS) study tract pancreatic identified by ICD-10 CM codes. Adjusted odds ratios (aORs) predefined...
Abstract Disclosure: N. Charoenngam: None. P. Likasitwatanakul: C. Kansuttiviwat: B. Ponvilawan: A. Jaroenlapnopparat: M. Tanariyakul: Mannstadt: Heterozygous germline loss-of-function mutations in the MAX gene, encoding tumor suppressor MYC-associated factor X, are associated with hereditary pheochromocytoma-paraganglioma (PCC/PGL) syndrome. Furthermore, there reports of patients who developed additional endocrine and non-endocrine tumors. Thus, presence multiple tumors has been proposed to...
Abstract Multi-gene panel testing has led to the detection of pathogenic/likely pathogenic (P/LP) variants in many cancer susceptibility genes patients with breast-ovarian spectrum. However, clinical and genomic data Asian populations including Thai was underrepresented significance multi-gene Thailand remains undetermined. In this study, we collected genetic from 4,567 hereditary (HBOC) spectrum who underwent testing. Six hundred ten individuals (13.4%) had germline P/LP variants. Detection...