A5086260281- Hemoglobinopathies and Related Disorders
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Iron Metabolism and Disorders
- Platelet Disorders and Treatments
- Chronic Myeloid Leukemia Treatments
- Chronic Lymphocytic Leukemia Research
- Venous Thromboembolism Diagnosis and Management
- Blood groups and transfusion
- Neutropenia and Cancer Infections
- CNS Lymphoma Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Acute Lymphoblastic Leukemia research
- Telomeres, Telomerase, and Senescence
- Multiple Myeloma Research and Treatments
- Mycobacterium research and diagnosis
- Cutaneous lymphoproliferative disorders research
- Viral-associated cancers and disorders
- Glioma Diagnosis and Treatment
- T-cell and Retrovirus Studies
- Childhood Cancer Survivors' Quality of Life
- Hematopoietic Stem Cell Transplantation
- CAR-T cell therapy research
- Kruppel-like factors research
Chiang Mai University
2016-2025
Ospedale A. Perrino
2019
Maharaj Nakorn Chiang Mai Hospital
2019
Dengue infection patients are presented with acute febrile illness. Clinical presentations may mimic other infections. The serology for definite diagnosis is costly and inaccessible in many hospitals. We sought to identify the clinical features hematologic parameters from a complete blood count (CBC) which distinguish dengue causes.This was retrospective single center study Chiang Mai University Hospital. All who fever between September 2013 July 2015 were included. of must be confirmed by...
Background Cerebral venous sinus thrombosis (CVST) is a rare type of that affects the cerebral system. The data on neurological outcomes are limited. Objectives This study aimed to investigate CVST, contributing factors, clinical presentation, treatment and mortality. Methods was single-center, retrospective at university-based referral hospital in Thailand. Consecutive patients diagnosed with CVST between January 2010 December 2020 were included. Outcomes measured by modified Rankin Scale...
Introduction: Pediatric acute lymphoblastic leukemia (ALL) has cure rates exceeding 90%, while adult ALL a 3-year survival rate of only 40–50%. Adolescents and young adults (AYAs) face unique challenges due to age-related factors high-risk disease features. Although pediatric-inspired regimens improve survival, intensive chemotherapy increases susceptibility severe infections. Methods: A retrospective analysis was conducted on AYA-ALL patients treated at Chiang Mai University Hospital from 1...
Aim: Exposure to fine particulate matter, particularly PM2.5, has been associated with increased platelet activation and cardiovascular risks. However, its effect on recovery after transfusion remains unclear. Purpose: This study aims assess the influence of PM2.5 exposure in patients hematologic malignancies receiving prophylactic transfusions. Patients Methods: We conducted a cross-sectional involving 66 who developed chemotherapy-induced thrombocytopenia received transfusions between...
ABSTRACT Introduction Data regarding long‐term clinical outcomes in Asian patients with acquired haemophilia A (AHA) was limited. Aim This study aimed to evaluate the effectiveness of current treatments and their a real‐world setting among Thai AHA. Methods retrospective cohort conducted at university‐based hospital. Patients’ characteristics, treatment patterns disease were collected. Univariate multivariate Gray's competing risk analyses used examine factors related time response. Results...
Anticoagulant prescription and management are crucial steps of venous thromboembolism (VTE). The Clinical decision support systems (CDSS) designed developed to aid healthcare professionals in making informed decisions. To develop assess the efficacy mobile app-based CDSS for VTE. A randomized controlled trial was conducted, enrolling participants aged ≥ 20 years who were one following categories: medical student, intern, internal medicine resident, or hematology fellow. Participants randomly...
Background: Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders characterized by proliferation of one or more myeloid lineages. Polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF) classical Philadelphia chromosome (Ph)-negative MPN that have a Janus Kinase 2 (JAK2) mutation, especially JAK2V617F in the majority patients. The major complications Ph-negative MPNs thrombosis, hemorrhage, leukemic transformation. Objective: To study...
Background A common complication of thalassemia is secondary osteoporosis. This study aimed to assess the prevalence and factors associated with low BMD in thalassemic patients. Method a cross-sectional study. Eligible patients were males aged within 18–49 years or premenopausal women diagnosed Chiang Mai University Hospital between July 2021 2022. The diagnosis by dual-energy x-ray absorptiometry (DXA) was defined as Z-score -2.0 SD lower either lumbar spine femoral neck. Clinical analyzed...
Introduction Elevated ambient pollution exposure is potentially linked to thromboembolism. However, the mechanisms by which particulate matter (PM) interferes with balance of hemostatic system remain unclear. This study investigates PM-mediated changes in individuals across unique seasonal variations pollution. Methods prospective was conducted between February and July 2020 during alterations Chiang Mai, Thailand. Blood tests from 30 healthy subjects were assessed at four-week intervals,...
Diffuse large B-cell lymphoma (DLBCL) is an aggressive type of non-Hodgkin (NHL) that accounts for approximately 25–40% all NHL cases. The objective this study was to investigate the protein expression, clinical impact, and prognostic role MYC, BCL2, Ki-67 in Thai DLBCL patients. A retrospective analysis conducted on 100 patients diagnosed between January 2018 December 2019. Immunohistochemistry used assess expression Ki-67. revealed a significant association extranodal involvement positive...
To study the clinical manifestations, outcomes, and survival of warm-type autoimmune hemolytic anemia (AIHA) patients.This was a retrospective single-center from 2002 to 2013. Clinical data AIHA patients were reviewed analyzed.One hundred one included, whom 77% female with median age 43 years. Primary found in 61% patients. The secondary causes systemic lupus erythematosus (SLE) (64%), solid malignancies (13%), lymphomas (10%), drugs (8%), infections (5%). Most (96%) responded steroids,...
The intestinal bacterial flora of febrile neutropenic patients has been found to be significantly diverse. However, there are few reports alterations in adult acute myeloid leukemia (AML) patients. Stool samples each treatment-naïve AML patient were collected the day before initiation induction chemotherapy (pretreatment), on first date fever and bone marrow recovery. Bacterial DNA was extracted from stool 16s ribosomal RNA genes sequenced by next-generation sequencing. Relative abundance,...
Background. Nontransfusion dependent thalassemia (NTDT) is a milder form of that does not require regular transfusion. It associated with many complications, which differ from found in transfusion-dependent (TDT). Currently available information mostly derived beta-NTDT; consequently, more data needed to describe complications the alpha-NTDT this disease. Methods . We retrospectively reviewed medical records NTDT patients January 2012 December 2013. Complications related were and compared....
Establishment and analysis of mean platelet volume (MPV) may be helpful in the discrimination between underproduction or over-destruction platelets as causes thrombocytopenia. The primary objective is to find cut-off point MPV for distinguishing secondary validate value by using bone marrow examination. Thrombocytopenic patients were enrolled a training set receiving operating characteristics (ROC) curve was plotted obtain MPV. A validation recruited value. included 240 patients. Half with...
Background Thalassemia is the most prevalent hereditary anaemia worldwide. Severe forms of thalassemia can lead to reduced life expectancy due disease-related complications.
Hyperuricemia is a common complication of hematologic malignancies, and hyperuricosuria in this population has shown conflicting results. This study aimed to determine the prevalence hyperuricemia parameters associated with serum uric acid (SUA) urine (UUA) patients lymphoma myeloproliferative neoplasms (MPN).
Objectives To evaluate any association between pre-transfusion hemoglobin (Hb) levels and thalassemia complications to identify the Hb cutoff values predict complications.Methods We performed a cross-sectional study in patients who attended Adult Hematology Clinic of tertiary care University Hospital from October 2017 2018. A point-biserial correlation was used complications. receiver operating characteristic (ROC) curve diagnostic ability values.Results Out 102 patients, there were 53...
BACKGROUND Autologous stem cell transplantation (ASCT) has become a standard procedure in multiple myeloma (MM) patients. Cryopreservation (CRYO) of cells may be associated with adverse reactions dimethyl sulfoxide. Previous studies showed that storage at 4°C (non-cryopreserved [NC] method) have some advantages. This analysis focused on comparing the transplant-related outcomes 2 preservation methods. MATERIAL AND METHODS was cohort study consecutive MM patients who underwent ASCT Chiang Mai...
Abstract Hepcidin is a key iron-regulatory hormone, the production of which controlled by iron stores, inflammation, hypoxia and erythropoiesis. The regulation hepcidin clinical importance in thalassemia patients anemia occurs along with overload. present study aimed to evaluate correlation between serum ferritin levels patients. This cross-sectional investigated 64 thalassemia; 16 β-thalassemia major (BTM), 31 β-thalassemia/hemoglobin (Hb) E (BE), 17 Hb H + AE Bart’s disease (Hb Bart’s)....
This study aims to find the cut-off value and diagnostic accuracy of use RDW as initial investigation in enabling differentiation between IDA NTDT patients. Patients with microcytic anemia were enrolled training set used plot a receiving operating characteristics (ROC) curve obtain RDW. A second patients included validation analyze accuracy. We recruited 94 64 into set. The area under ROC was 0.803. best diagnosis >21.0% sensitivity specificity 81.3% 55.3% respectively. In set, there 34 58...