A5048707776- Attention Deficit Hyperactivity Disorder
- Congenital heart defects research
- Coronary Artery Anomalies
- Congenital Heart Disease Studies
- Autism Spectrum Disorder Research
- Child and Adolescent Psychosocial and Emotional Development
- Children's Physical and Motor Development
- Genetics and Neurodevelopmental Disorders
- Functional Brain Connectivity Studies
- Metabolism and Genetic Disorders
- Neuroethics, Human Enhancement, Biomedical Innovations
- Neural and Behavioral Psychology Studies
- Genomic variations and chromosomal abnormalities
- Behavioral and Psychological Studies
- Diet and metabolism studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Treatment of Major Depression
- Family and Disability Support Research
- Cognitive Abilities and Testing
- Mitochondrial Function and Pathology
- Adolescent and Pediatric Healthcare
- Perfectionism, Procrastination, Anxiety Studies
- LGBTQ Health, Identity, and Policy
- Child Nutrition and Feeding Issues
- Neuroscience and Neuropharmacology Research
Syracuse University
2016-2025
SUNY Upstate Medical University
2012-2024
Cardiff University
2021
Illinois Institute of Technology
2020
Centre for Addiction and Mental Health
2014
University of Geneva
2014
University Health Network
2014
University of Toronto
2014
State University of New York
2009-2013
Fundación Juan March
2011
Patients with 22q11.2 deletion syndrome (22q11DS) have an elevated (25%) risk of developing schizophrenia. Recent reports suggested that a subgroup children 22q11DS display substantial decline in cognitive abilities starting at young age.
Attention deficit/hyperactivity disorder (ADHD) and autism spectrum (ASD) commonly co-occur. With the DSM-5, clinicians are permitted to make an ASD diagnosis in context of ADHD. In earlier versions DSM, this was not acceptable. Both ADHD reported have had substantial increases prevalence within past 10 years. As a function both increased disorders as well ability ADHD, there has been significant amount research focusing on comorbidity between few Here, we provide update biological,...
Abstract The 22q11.2 deletion (22q11DS) is a common chromosomal microdeletion and potent risk factor for psychotic illness. Prior studies reported widespread cortical changes in 22q11DS, but were generally underpowered to characterize neuroanatomic abnormalities associated with psychosis and/or effects of variability size. To address these issues, we developed the ENIGMA (Enhancing Neuro Imaging Genetics Through Meta-Analysis) Working Group, representing largest analysis brain structural...
Diagnosing ADHD based primarily on symptom reports assumes that the number/frequency of symptoms is tied closely to impairment imposed an individual’s functioning. That presumed linkage encourages diagnosis more by Diagnostic and Statistical Manual Mental Disorders (4th ed.) style lists than well-defined, psychometrically sound assessments impairment. The current study correlated measures reflecting each construct in four separate, large-scale research samples. Average correlation between...
Objective: To assess the influence of psychiatric comorbidity on social skill treatment outcomes for children with autism spectrum disorders (ASDs). Methods: A community sample 83 (74 males, 9 females) an ASD (mean age = 9.5 yr; SD 1.2) and common comorbid participated in 10-week skills training groups. The first 5 weeks group focused conversation second problem solving skills. concurrent parent was also included treatment. Social were assessed using Skills Rating System. Ratings completed...
Certain copy number variants (CNVs) greatly increase the risk of autism. The authors conducted a genetics-first study to investigate whether heterogeneity in clinical presentation autism is underpinned by specific genotype-phenotype relationships.
Objective: 22q11.2 deletion syndrome (22q11DS) is among the strongest known genetic risk factors for schizophrenia. Previous studies have reported variable alterations in subcortical brain structures 22q11DS. To better characterize 22q11DS, including modulating effects of clinical and heterogeneity, authors studied a large multicenter neuroimaging cohort from ENIGMA Deletion Syndrome Working Group. Methods: Subcortical were measured using harmonized protocols gross volume shape morphometry...
Evaluated efficacy of social skills training (SST) on children with 2 subtypes attention deficit hyperactivity disorder (ADHD). Participants were 120 (30 girls, 90 boys), ages 8 to 12 ADHD-Inattentive type (ADHD-I; n = 59) or Combined (ADHD-C; 61). The randomly assigned within diagnosis subtype the treatment condition (8 weeks SST) no-intervention control condition. SST led greater improvements in both parent- and child-perceived assertion ADHD, yet did not affect other domains competence....
Treatment adherence is a significant challenge within the field of paediatrics. Culture an important clinical variable to consider in treatment and medical regimens. Consideration common elements Latino culture viable mechanism improving adherence. These shared include language, familismo, respeto, personalismo, espiritism, simpatia, fatalismo , crisis orientation. In addition, acculturation presented as it pertains Each cultural discussed means importance culturally competent care...
Diagnosing ADHD in adults is difficult when the diagnostician cannot establish an onset prior to DSM‐IV criterion of age seven or if number symptoms does not achieve DSM threshold for diagnosis. These diagnostic issues are even larger concern clinicians faced with substance use disorders (SUD). The present study compared four groups adults: full subjects who met all criteria childhood ADHD, late except at criterion, subthreshold did meet symptom criteria, and non‐ADHD any above criteria....
Background: The aim of this study was to assess the validity diagnosing attention deficit/hyperactivity disorder (ADHD) in high IQ children and further characterize clinical features associated with their ADHD. Methods: We operationalized giftedness/high as having a full scale ≥120. identified 92 who did not have ADHD 49 that met diagnostic criteria for had participated Massachusetts General Hospital Longitudinal Family Studies Results: Of our participants IQ, majority ( n = 35) Combined...
Objective: To assess the efficacy of cognitive behavioral therapy (CBT) for managing adolescent ADHD. Method: A total 68 adolescents with ADHD and associated psychiatric comorbidities completed a manualized CBT treatment protocol. The intervention used in study was downward extension Safren et al. program adults who have symptoms unresolved by medication. Outcome variables consisted narrow band (ADHD) broadband (e.g., mood, anxiety, conduct) symptom measures (Behavior Assessment System...
.This study examined academic and social impairments of 6- to 11-year-old children with attention deficit hyperactivity disorder (ADHD; n = 101) versus other referred without ADHD (n 53) controls 24). Parent teacher ratings showed significantly lower performance functioning for compared controls. Children scored than on standardized tests reading/language, mathematics, written language, mathematics. In multiple regression analyses, cognitive ability accounted the most variance in predicting...
Abstract 22q11.2 deletion syndrome (22q11DS)—a neurodevelopmental condition caused by a hemizygous on chromosome 22—is associated with an elevated risk of psychosis and other developmental brain disorders. Prior single-site diffusion magnetic resonance imaging (dMRI) studies have reported altered white matter (WM) microstructure in 22q11DS, but small samples variable methods led to contradictory results. Here we present the largest study ever conducted dMRI-derived measures WM 22q11DS (334...