A5101391934- Nanoparticle-Based Drug Delivery
- Cancer, Lipids, and Metabolism
- Cell death mechanisms and regulation
- Ferroptosis and cancer prognosis
- RNA modifications and cancer
- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Field-Flow Fractionation Techniques
- Cancer therapeutics and mechanisms
Shanghai Jiao Tong University
2024
Shanghai First People's Hospital
2024
Sichuan University
2024
Immune checkpoint inhibitors (ICIs) provide modest but unsatisfactory benefits for extensive-stage small cell lung cancer (ES-SCLC). Developing strategies treating ES-SCLC is critical.
Abstract Introduction Esophageal cancer is one of the major cancers in China. Most patients with esophageal are diagnosed at an advanced stage, and 5 year survival rate discouraging. Combined chemotherapy a common method for treatment cancer. Methods In this study, distearoyl phosphatidyl ethanolamine polyethylene glycol 2000 (DSPE‐PEG2000) nanoliposomes (NLPs) encapsulating anticancer drugs docetaxel (DOX) oridonin (ORD) were prepared, their ability to enhance release was determined. The...
Abstract Background Lovastatin, a type of statin usually considered as lipid‐lowering drug that lowers blood cholesterol and low‐density lipoprotein levels, has been rediscovered to have anticancer activity. Fewer studies exist regarding the effect lovastatin on esophageal squamous cell carcinoma (ESCC). Methods Here, we report shows ESCC By affecting mitochondrial autophagy pathway. Moreover, based proteomics computer molecular simulations found RAB38 RAB27A may be target lovastatin....