Mustafa G. Bulbul

ORCID: 0000-0002-1148-1896
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About
Contact & Profiles
Research Areas
  • Head and Neck Cancer Studies
  • Salivary Gland Tumors Diagnosis and Treatment
  • Head and Neck Surgical Oncology
  • Obstructive Sleep Apnea Research
  • Sinusitis and nasal conditions
  • Tracheal and airway disorders
  • Allergic Rhinitis and Sensitization
  • Nasal Surgery and Airway Studies
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Cancer Diagnosis and Treatment
  • Voice and Speech Disorders
  • Ear and Head Tumors
  • Dental Anxiety and Anesthesia Techniques
  • Colorectal and Anal Carcinomas
  • Cerebral Venous Sinus Thrombosis
  • Teratomas and Epidermoid Cysts
  • Genetic and rare skin diseases.
  • Kidney Stones and Urolithiasis Treatments
  • Genetics and Neurodevelopmental Disorders
  • Hearing, Cochlea, Tinnitus, Genetics
  • Vestibular and auditory disorders
  • Sleep and Wakefulness Research
  • Orthopedic Infections and Treatments
  • Cerebrospinal fluid and hydrocephalus
  • Dysphagia Assessment and Management

West Virginia University
2020-2025

Harvard University
2018-2022

Massachusetts Eye and Ear Infirmary
2018-2022

King Faisal Specialist Hospital & Research Centre
2020

Istanbul Medipol University
2019

University Medical Center Utrecht
2018

Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi
2013

<h3>Importance</h3> Given that early-stage oral cavity squamous cell carcinoma (OCSCC) has a high propensity for subclinical nodal metastasis, elective neck dissection become standard practice many patients with clinically negative nodes. Unfortunately, most without regional this risk-averse treatment paradigm results in unnecessary morbidity. <h3>Objectives</h3> To develop and validate predictive models of occult metastasis from clinicopathological variables were available after surgical...

10.1001/jamanetworkopen.2022.7226 article EN cc-by-nc-nd JAMA Network Open 2022-04-13

Approximately 1 in 5 new patients with head and neck cancer (HNC) the US belong to racial ethnic minority groups, but their survival rates are worse than White individuals. However, because most studies compare Black vs patients, little is known about differences among members of groups.To describe differential identify nonclinical factors associated stage presentation HNC belonging groups.This population-based retrospective cohort study used data from 2007 2016 Surveillance, Epidemiology,...

10.1001/jamaoto.2021.3425 article EN JAMA Otolaryngology–Head & Neck Surgery 2021-12-24

ABSTRACT Background Human papillomavirus (HPV) negative oropharyngeal squamous cell carcinoma (OPSCC) is associated with worse survival when compared to HPV‐positive OPSCC. Primary surgery one option intensify therapy in this high‐risk group of patients. Unfortunately, the only randomized trial explore approach (RTOG 1221) failed accrue and role primary treatment HPV‐negative OPSCC remains unanswered. Methods A systematic review meta‐analysis were performed examine outcomes We used PRISMA...

10.1002/hed.28088 article EN Head & Neck 2025-01-27

Objectives/Hypothesis To investigate the definition of a clear margin and use frozen section (FS) among practicing head neck surgeons in oral cancer management. Study Design Cross‐sectional survey. Methods We designed survey that was sent to American Head Neck Society (AHNS) members via an email link. Results A total 185 (13% 1,392) AHNS completed our Most surveyed (96.8%) FS supplement cavity squamous cell carcinoma resections. Fifty‐five percent prefer specimen‐based approach. The majority...

10.1002/lary.28976 article EN The Laryngoscope 2020-08-22

Studies on the impact of rapid on-site evaluation (ROSE) during endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) lymph nodes are retrospective and have shown conflicting results. We aimed to compare diagnostic yield EUS-FNA with ROSE (ROSE+) without (ROSE-).This was a multicenter, randomized controlled trial. Consecutive patients who were scheduled undergo mediastinal or abdominal ROSE+ ROSE-. In group, number passes dictated by cytotechnician. ROSE- five performed interference...

10.1038/s41395-018-0025-8 article EN The American Journal of Gastroenterology 2018-04-18

<h3>BACKGROUND AND PURPOSE:</h3> For primary squamous cell carcinoma of the oral tongue, accurate assessment tumor thickness and depth invasion is critical for staging operative management. Currently, typical imaging modalities used preoperative are CT MR imaging. Intraoperatively, or cannot provide real-time guidance, by manual palpation limited in precision. We investigated whether intraoperative sonography a feasible technique validated its accuracy comparing it with histopathologic...

10.3174/ajnr.a6625 article EN cc-by American Journal of Neuroradiology 2020-06-18

Rett syndrome (RTT) is a severe neurodevelopmental disorder reported worldwide in diverse populations. RTT diagnosed primarily females, with clinical findings manifesting early life. Despite the variable rates across populations, has an estimated prevalence of ∼1 10,000 live female births. Among 215 Saudi Arabian patients and autism spectrum disorders, we identified 33 who were subsequently examined by genome-wide transcriptome mitochondrial genome variations. To best our knowledge, this...

10.1089/omi.2019.0192 article EN OMICS A Journal of Integrative Biology 2020-02-27

Objectives/Hypothesis To investigate the impact of specific treatment‐related variables on functional and quality life outcomes in oral cavity cancer (OCC) patients. Study Design Retrospective Cohort. Methods Patients with primary OCC at least 6 months after resection adjuvant therapy were included. completed surveys including Speech Handicap Index (SHI), M.D. Anderson Dysphagia Inventory (MDADI), Functional Assessment Cancer Therapy‐Head Neck (FACT‐HN). Performance Status Scale (PSS) tongue...

10.1002/lary.29573 article EN The Laryngoscope 2021-04-21

To describe a 10-year single center experience with parotid gland malignancies and to determine factors affecting outcomes.Retrospective review.The institutional cancer registry was used identify patients treated surgically for of the between January 2005 December 2014. Clinical pathologic data were collected retrospectively from patient charts analyzed their association overall survival (OS) disease-free (DFS).Two hundred identified. Mean age at surgery 57.8 years, mean follow-up time 52...

10.1002/lio2.326 article EN cc-by-nc-nd Laryngoscope Investigative Otolaryngology 2019-11-13

In clinically localized (T1-2) oral cavity squamous cell carcinoma (OCSCC), regional lymph node metastasis is associated with a poor prognosis. Given the high propensity of subclinical nodal disease in these patients, upfront elective neck dissections (END) for patients node-negative are common and better outcomes. Unfortunately, even this risk-adverse treatment paradigm, recurrence still occurs, our understanding factors that modulate risk alter survival have yet to be fully elucidated.To...

10.1001/jamaoto.2022.2312 article EN JAMA Otolaryngology–Head & Neck Surgery 2022-09-08

Abstract Objective To report our experience on the complications of primary pediatric endoscopic sinus surgery (ESS). Methods Case series ESS performed from 1991 to 2016 children who failed maximal medical therapy and/or adenoidectomy. Inclusion criteria were (age &lt;12 years old) underwent with or without adenoidectomy for chronic rhinosinusitis (CRS) after All patients maxillary antrostomy ± partial total ethmoidectomy. Patients complicated acute excluded. Complications reviewed included:...

10.1002/lio2.791 article EN cc-by-nc-nd Laryngoscope Investigative Otolaryngology 2022-03-29

cidence is 4-29/100,000 patients/year (11).Cartilage and subchondral bone damage begin within 24-48 hours if appropriate antibiotic therapy not applied (6).Joint drainage are the basis of treatment (12).Septic arthritis has a mortality rate 11-40% without (2, 13).In addition to patient-related risk Is Intraarticular Antibiotic Administration Effective in Treatment Methicillin-Resistant Staphylococcus aureus?

10.55095/achot2019/046 article EN Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 2019-08-01

Abstract Meniere's disease (MD) is a complex inner ear related to endolymphatic hydrops and with multiple other etiologies suggested including autoimmunity vascular insufficiency. Statins are lipid‐lowering medications additional effects reduction of oxidative stress inflammation. We performed cross‐sectional study comparing patients MD on statins those not see if there any difference in activity (major vertigo spells) hearing stage utilizing linear logistic regression. Our analysis showed...

10.1002/oto2.177 article EN cc-by-nc-nd OTO Open 2024-07-01

Investigate whether nonopioid analgesics (NOA) provide adequate pain control after otologic surgery.

10.1097/mao.0000000000004344 article EN Otology & Neurotology 2024-11-08
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