A5004128345- Esophageal and GI Pathology
- Gastroesophageal reflux and treatments
- Dysphagia Assessment and Management
- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Esophageal Cancer Research and Treatment
- Eosinophilic Esophagitis
- Salivary Gland Tumors Diagnosis and Treatment
- Tracheal and airway disorders
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Surgical Treatments
- Gastrointestinal disorders and treatments
- Lung Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Cardiovascular Function and Risk Factors
- Diet and metabolism studies
- Metastasis and carcinoma case studies
- Head and Neck Cancer Studies
- Diverticular Disease and Complications
- Foreign Body Medical Cases
- Clinical Nutrition and Gastroenterology
- Lung Cancer Research Studies
- Abdominal Surgery and Complications
- Pain Management and Opioid Use
- Glycogen Storage Diseases and Myoclonus
University Medical Center Utrecht
2014-2019
Summary Background A previous single‐centre study showed that lower oesophageal sphincter electrical stimulation therapy (LES‐EST) in gastro‐oesophageal reflux disease (GERD) patients improves symptoms and decreases acid exposure. Aim To evaluate safety efficacy of LES‐EST GERD with incomplete response to proton pump inhibitors (PPIs) a prospective, international, multicentre, open‐label study. Methods patients, partially responsive PPIs, received LES‐EST. health‐related quality life...
<b>Background and aim:</b> Pneumatic dilation is a commonly used treatment in achalasia. Recent studies have shown that esophageal distensibility measurements can be to assess the effect of possibly risk perforation. A new hydraulic balloon allows visualization shape vivo measurement during dilation. We aimed evaluate technical feasibility 30-mm shape-measuring for <b>Methods:</b> Consecutive patients with newly diagnosed achalasia were dilated using balloon. Patients contacted 1 week,...
Surgical resection of upper gastrointestinal (GI) subepithelial tumors (SETs) is associated with significant morbidity and mortality. A new over-the-scope (OTS) clip can be used for endoscopic full-thickness (eFTR). We aimed to prospectively evaluate feasibility safety GI eFTR a new, flat-based OTS clip.Consecutive patients gastric or duodenal SET < 20 mm were included. After identification the lesion, was placed lesions resected. Patients followed 1 month assess severe adverse events...
Studies on the impact of rapid on-site evaluation (ROSE) during endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) lymph nodes are retrospective and have shown conflicting results. We aimed to compare diagnostic yield EUS-FNA with ROSE (ROSE+) without (ROSE-).This was a multicenter, randomized controlled trial. Consecutive patients who were scheduled undergo mediastinal or abdominal ROSE+ ROSE-. In group, number passes dictated by cytotechnician. ROSE- five performed interference...
Abstract Background and study aims Sealing esophageal leaks by stent placement allows healing in 44 % – 94 of patients. We aimed to develop a prediction rule predict the chance successful therapy. Patients methods In this multicenter retrospective cohort study, patients with benign upper gastrointestinal leakage treated were included. used logistic regression analysis including four known clinical predictors therapy outcome. The model performance was evaluated an independent validation...
<b>Background and aims</b> In multiple endocrine neoplasia type 1 (MEN1), endoscopic ultrasound (EUS) is used for identification follow-up of pancreatic neuroendocrine tumors (PNETs). The role EUS in surveillance small ( < 20 mm) PNETs unclear, mostly because the natural course these lesions largely unknown. We aimed to determine annual growth incidence rate patients with MEN1 using EUS-based surveillance. <b>Patients methods</b> Linear array procedures between 2002 2015 were identified....
Abstract Background and study aims We aimed to evaluate the feasibility safety of a new, flat-based over-the-scope clip (Padlock Clip) for colorectal endoscopic full-thickness resection (eFTR). Patients methods prospectively included 26 patients with lesions < 20 mm. Indications eFTR were re-resection scar low risk malignant polyp (n = 11), recurrent adenoma in non-lifting 10), 4), an located diverticulum 1). Results Technical success rate 100 % (26/26) 92 (24/26), respectively. Median...
Background and study aims Fully covered self-expanding metal stents (FCSEMS) provide an alternative to bougie dilation (BD) for refractory benign esophageal strictures. Controlled studies comparing temporary placement of FCSES repeated BD are not available. Patients methods with anastomotic strictures, dysphagia scores ≥ 2, two five prior were randomized 8 weeks FCSEMS or BD. The primary endpoint was the number during 12 months after baseline treatment. Results Eighteen patients included...
Increasing evidence suggests that esophagogastric junction (EGJ) distensibility is predictive of long-term clinical success after achalasia treatment. A new commercially available hydraulic dilation balloon capable measuring EGJ opening diameters whilst simultaneously dilating the EGJ. Deployed alongside endoscope under direct visualization, it used for lower esophageal sphincter in patients with achalasia. Impedance measurement electrodes are incorporated catheter shaft balloon, which...