- Lung Cancer Research Studies
- Adrenal and Paraganglionic Tumors
- Breast Lesions and Carcinomas
- Cancer and Skin Lesions
- Pituitary Gland Disorders and Treatments
- Breast Cancer Treatment Studies
- Cardiac tumors and thrombi
- Metastasis and carcinoma case studies
- Proteoglycans and glycosaminoglycans research
- Male Breast Health Studies
- Cancer, Hypoxia, and Metabolism
- Neonatal Respiratory Health Research
- Brain Metastases and Treatment
- Chronic Lymphocytic Leukemia Research
- Tumors and Oncological Cases
- Heart Failure Treatment and Management
- Polyomavirus and related diseases
- Ultrasound and Hyperthermia Applications
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Immunodeficiency and Autoimmune Disorders
- Gastrointestinal Tumor Research and Treatment
- Head and Neck Anomalies
- IgG4-Related and Inflammatory Diseases
- Cell Adhesion Molecules Research
- Gastrointestinal disorders and treatments
Loyola University Medical Center
2018-2020
NYU Langone Health
2020
Rush University Medical Center
2016-2019
Rush University
2019
SUNY Upstate Medical University
2013-2017
In this study, we first generated and characterized a polyclonal antibody against unique domain of matrlin-2 then used specific to assess the expression pattern matrilin-2 by immunohistochemistry. We found that marilin-2 is widely distributed in connective tissues many mouse including heart, colon, penis, esophagus, lung, kidney, tracheal cartilage, developmental bone, adult bone. The level was remarkably increased osteoarthritis articular compared normal healthy tissues. Furthermore,...
The abscopal effect has previously been described in various tumors and is associated with radiation therapy hyperthermia, possible underlying mechanisms explaining each observed case. In the present study, we aimed to investigate antitumor effects of magnet-mediated hyperthermia on Walker-256 carcinosarcomas rats at two different temperature ranges (42-46°C 50-55°C). We also identify whether a higher therapeutic magnetic-mediated improves effects, where localised irradiation tumor causes...
Autophagy is a protective cellular mechanism in response to various stresses, including sepsis. Sepsis defined as systemic inflammation by infection. Surfactant protein A and D (SP-A SP-D) are involved host defense, regulation of inflammation, homeostasis, but their roles the autophagic activity relevant gene expression sepsis unclear. In this study, mice lacking SP-A SP-D (SP-A/D KO mice) background-matched wild-type (WT) C57BL/6 underwent either cecal ligation puncture (CLP) or sham...
Ectopic thyroid tissue is rare and controversial. Some experts consider it to always be metastatic carcinoma, whereas others benign as long restricted few follicles without cytoarchitectural features of papillary carcinoma. Immunohistochemistry (IHC) molecular studies have not yet been performed further characterize this entity. We retrospectively searched our pathology files for all ectopic inclusions reviewed clinicopathologic characteristics concurrent pathologic findings. identified 8...
Synchronous gastric tumors that consist of both gastrointestinal stromal tumor (GIST) and adenocarcinoma are rare. We studied the clinicopathological molecular characteristics six cases containing GIST. By means immunohistochemical analysis, all GIST cells expressed CD117, CD34 Dog1 in synchronous adenocarcinomas with GIST, alone. Sequencing analysis demonstrated exon 11 c-kit mutations were present two four five GISTs. One GISTs was an uncommon mutation CTT > CCA at amino acid 576, other a...
Context.— Amyloidoses are rare but heterogeneous disorders for which diagnosis is contingent upon the detection of deposits by Congo red stain and amyloid protein typing determines treatment options. Objective.— To address reporting bone marrow (BM) involvement in relation to spatial distribution explore whether location may have clinical relevance. Design.— We examined 66 BM biopsies positive with regard type amyloid, percentage clonality plasma cells, other organ involvement, relevant...
Meningeal carcinomatosis (MC) is a rare complication in breast cancer patients. It defined as diffuse or multifocal leptomeningeal metastasis.From our institution database, we retrospectively studied 19 patients diagnosed with MC the cerebrospinal fluid (CSF) 1997-2015, order to evaluate tumor prognostic markers, histologic subtypes, and clinical outcome.All were female, mean age of 53 years (range 36-75 years). The interval between diagnosis carcinoma was 28 months 6-62 months). median...
BACKGROUND:Metaplastic breast carcinoma is a rare entity characterized by rapid growth and heterogeneous histological features. It comprises less than 1% of all cancers, no definitive treatment has yet been identified. CASE REPORT:We describe here patient who presented with acute hypercalcemia was found to have large ulcerated mass. Once the patient’s stabilized, she underwent complete surgical resection that revealed large, cavitary, necrotic mass measuring over 11 cm. The final pathology...