A5100460923- Nanoplatforms for cancer theranostics
- ZnO doping and properties
- Boron and Carbon Nanomaterials Research
- Ga2O3 and related materials
- Ultrasound and Hyperthermia Applications
- Nanoparticle-Based Drug Delivery
- High-pressure geophysics and materials
- Inorganic Chemistry and Materials
- Metal and Thin Film Mechanics
- Extracellular vesicles in disease
- Perovskite Materials and Applications
- Rare-earth and actinide compounds
- Hemoglobin structure and function
- Porphyrin and Phthalocyanine Chemistry
- Dendrimers and Hyperbranched Polymers
- GaN-based semiconductor devices and materials
- Gas Sensing Nanomaterials and Sensors
- Advanced Chemical Physics Studies
- Graphene and Nanomaterials Applications
- Analytical Chemistry and Sensors
- Advanced Nanomaterials in Catalysis
- Inorganic Fluorides and Related Compounds
- Luminescence and Fluorescent Materials
- Catalytic Processes in Materials Science
- Cancer Cells and Metastasis
Hefei National Center for Physical Sciences at Nanoscale
2024-2025
University of Science and Technology of China
2020-2025
Jilin University
2014-2024
Fudan University
2022-2024
Second Affiliated Hospital of Soochow University
2024
Soochow University
2024
State Key Laboratory of Supramolecular Structure and Materials
2021-2023
Union Hospital
2018-2022
Capital Medical University
2022
Union Hospital
2018-2020
Black phosphorus nanosheets (BPNSs) have been actively employed as nanomedicine agents for photothermal and photodynamic therapy by virtue of their unique optical properties. However, chemical reactivity a competent biomaterial has not fully explored yet. Here, we report on the use BPNSs reactive oxygen species (ROS) scavengers to cure acute kidney injury (AKI) in mice. Importantly, vivo analysis mice revealed that were preferably accumulated kidney. We found alleviated...
Abstract Gold nanorods are effective photothermal agents in diagnosis and treatment of cancer due to their specific near-infrared laser absorption. However, tumor therapy by alone is lack targeting. Here, we described a novel nanocomplex made up gold nanorods, porphyrin, trastuzumab, called TGNs investigated the TGN-mediated as potential alternative targeting HER2-positive breast cancers. By conjugating trastuzumab porphyrin surface have increased specificity amplified detecting...
Solid-phase extraction (SPE) is an effective sample preparation method for removal of interfering compound and enrichment analyte. Liquid chromatography (LC) with various detectors a main separation detection technique used in the analytical field. This article reviews literatures about on-line coupling SPE LC. The advantages are reduction analysis time, contamination, analyte losses, as well improvement precision accuracy. sorbents including traditional materials, such chemically bonded...
Nitrides in many ways are fascinating since they often appear as superconductors, high-energy density, and hard materials. Though there exist a large variety of nitrides, noble gas nitrides missing nature. Pursuit has therefore become the subject topical interests, but remains great challenge molecular nitrogen (${\mathrm{N}}_{2}$, major form nitrogen) gases both inert systems do not interact at normal conditions. We show through first-principles swarm-structure search that high pressure...
Various nitrogen species in nitrides are fascinating since they often appear with these nitride as superconductors, hard materials, and high-energy density. As a typical complex, though iron has been intensively studied, the iron-nitrogen (Fe-N) compounds only have confined to single atom (N) or molecule (N
The development of cell-like nanoreactors with the ability to initiate biocatalytic cascades under special conditions holds tremendous potential for therapeutic applications. Herein, conformationally gated that respond acidic microenvironment infected diabetic wounds were developed by cucur[8]bituril (CB[8])-based supramolecular assembly. bioinspired exhibit not only self-regulated permeability and selectivity control internal enzyme activities substance exchange but also distinct binding...
Abstract Photoswitchable catalysis enables the non-invasive regulation of light-to-chemical energy conversion, where catalysts with wavelength-dependent photoexcitation behaviors are typically required. However, as for semiconductors, ultrafast hot-excited-species cooling, depicted Kasha's rule, tends to induce accumulation photoinduced species on lowest excited states, which brings about a detrimental effect achieving photoswitchable catalysis. Herein, by taking polymeric carbon nitride an...
Using ab initio evolutionary methodology for crystal structure prediction, we have found two ultra-incompressible hexagonal structures of $P{6}_{3}/mmc$ and $P\text{\ensuremath{-}}6m2$ ${\text{WN}}_{2}$, which are energetically much superior to previously proposed baddeleyite- cotunnite-type stable against decomposition into a mixture $\text{W}+{\text{N}}_{2}$ or $\text{WN}+1/2{\text{N}}_{2}$. The calculated large bulk modulus (e.g., 411 GPa) high hardness (36.8 GPa 36.6...
Using the angle-dispersive synchrotron x-ray powder diffraction technique in a diamond anvil cell, high-pressure behaviors of antimony telluride (Sb2Te3) are explored up to 52.7 GPa at room temperature. Three phases have been observed, about 8.0 GPa, 13.2 and above 21.6 respectively. Furthermore, crystalline structures these determined as monoclinic sevenfold C2/m phase, eightfold C2/c phase disordered body-centered cubic structure (space group Im − 3m) The phase-transition sequences...
Abstract High pressure can fundamentally alter the bonding patterns of chemical elements. Its effects include stimulating elements thought to be “inactive” form unexpectedly stable compounds with unusual and physical properties. Here, using an unbiased structure search method based on CALYPSO methodology density functional total energy calculations, phase stabilities crystal structures Li−Ar are systematically investigated at high up 300 GPa. Two unexpected Li m Ar n (LiAr 3 Ar) predicted...
Single-atom catalysts (SACs) that feature uniform metal active sites with symmetry configurations hold great promise in photocatalysis, while their catalytic efficiency is often restricted by the insufficient inherent activity. Drawing inspiration from hard-soft acid-base theory, here we propose delocalized electronic state of single-atom centers can be selectively modulated adjusting coordination symmetry, thereby optimizing adsorption and activation reactant molecules. By taking...
Ultraviolet electroluminescence was demonstrated from a p-ZnO:As/n-SiC(6H) heterojunction light-emitting diode at room-temperature. The p-ZnO:As fabricated by out-diffusion of arsenic atoms sandwiched GaAs interlayer on SiC substrate. p-type doping confirmed both Hall and low-temperature photoluminescence measurements. Under forward bias, an intense ultraviolet emission centered 384 nm achieved ZnO side the diode. Furthermore, light-output-current characteristic determined to evaluate...
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation Zhifeng Shi, Yuantao Zhang, Jinxiang Hui Wang, Bin Wu, Xupu Cai, Xijun Cui, Xin Dong, Hongwei Liang, Baolin Guotong Du; High-performance ultraviolet-blue light-emitting diodes based on an n-ZnO nanowall networks/p-GaN heterojunction. Appl. Phys. Lett. 8 July 2013; 103 (2): 021109....
Currently, multifunctional nanotechnology is strongly expected to improve the prospect of treatment and diagnosis. In this study, we synthesized epidermal growth factor (EGFR)-targeted phase-changeable polymer nanoparticles (C-HPNs) loaded with two drugs (C225 10-HCPT) for specific tumor targeting, synergistic chemotherapy, ultrasound imaging under low-intensity focused (LIFU). Cetuximab (C225), an EGFR-targeted monoclonal antibody, was conjugated on surface nanoparticles, leading a...
Tumor metastasis has become a major obstacle for the clinical treatment of malignant breast cancer. Thus, delivery system capable both antitumor and anti-metastasis efficacy is desired. In this work, low molecular weight heparin (LMWH)-based reduction-sensitive was developed, aiming to combine properties drug active excipients achieve synergistic anti-metastatic efficiency as well resolving potential adverse effects doxorubicin LMWH. That is, DOX could be enhanced its toxicity lowered....
Open AccessCCS ChemistryCOMMUNICATION1 Feb 2022Precise Detection and Visualization of Cyclooxygenase-2 for Golgi Imaging by a Light-Up Aggregation-Induced Emission-Based Probe Yuchao Luo†, Song Zhang†, Hui Wang, Quan Luo, Zhigang Xie, Bin Xu Wenjing Tian Luo† State Key Laboratory Supramolecular Structure Materials, Department Chemistry, Jilin University, Changchun 130012 , Zhang† Wang Luo Xie Polymer Physics Chemistry Institution, Institute Applied 130022 *Corresponding authors: E-mail...
Vertical conducting light-emitting diodes based on p-ZnO/n-GaN structure were fabricated conductive n-SiC(6H) substrates. The p-ZnO:As films prepared by arsenic out-diffusion from a sandwiched GaAs interlayer GaN/SiC template, and the AsZn-2VZn complex was considered to be most probable defect contributing p-type conductivity of ZnO:As films. Under forward bias, an intense ultraviolet emission at ∼384 nm ZnO side observed. electroluminescence performance diode remarkable in terms its low...
Morusin has been traditionally used for the treatment of Mycoplasma pneumoniae pneumonia (MPP), but underlying mechanism remains elusive. The present study aimed to explore by which morusin achieves efficacy on mycoplasma pneumonia. model was established in BALB/c mouse and effects were evaluated model. Compared with group, DNA amount M. decreased 24.6 ± 3.14% 47.6 6.78% low (20 mg/kg) high (50 groups, respectively (P<0.05). Moreover, led levels pro-inflammatory cytokines such as interleukin...
An ultrasound-activated oxygen generation nanosystem was developed to significantly reduce the myocardial infarction size as well promote cell survival and proliferation of cardiac cells after acute infarction.