Junli Lu

ORCID: 0009-0002-9268-9003
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About
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Research Areas
  • Data Mining Algorithms and Applications
  • Data Management and Algorithms
  • Maternal and fetal healthcare
  • Pregnancy and preeclampsia studies
  • Ectopic Pregnancy Diagnosis and Management
  • Maternal and Perinatal Health Interventions
  • Rough Sets and Fuzzy Logic
  • Virtual Reality Applications and Impacts
  • Video Analysis and Summarization
  • Complex Network Analysis Techniques
  • Uterine Myomas and Treatments
  • Tactile and Sensory Interactions
  • Advanced Text Analysis Techniques
  • Pancreatitis Pathology and Treatment
  • Endometrial and Cervical Cancer Treatments
  • Topic Modeling
  • Circular RNAs in diseases
  • Text and Document Classification Technologies
  • Natural Language Processing Techniques
  • Cancer Risks and Factors
  • MicroRNA in disease regulation
  • Recommender Systems and Techniques
  • Medical Research and Treatments
  • Data Visualization and Analytics
  • Image Retrieval and Classification Techniques

Tongji Hospital
2024-2025

Huazhong University of Science and Technology
2024-2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2002-2025

The Second Nanning People's Hospital
2023-2025

Southwest Jiaotong University
2024

Beijing Chao-Yang Hospital
2013-2024

Sichuan University
2024

West China Hospital of Sichuan University
2024

Communication University of China
2023-2024

Ministry of Education of the People's Republic of China
2024

Abstract Paradoxically, tumor development and progression can be inhibited promoted by the immune system. After three stages of editing, namely, elimination, homeostasis escape, cells are no longer restricted surveillance thus develop into clinical tumors. The mechanisms escape include abnormalities in antitumor-associated cells, selection for resistance to impaired transport T formation an immunosuppressive microenvironment. A population distinct immature myeloid myeloid-derived suppressor...

10.1186/s40164-024-00505-7 article EN cc-by Experimental Hematology and Oncology 2024-04-12

Co-creation with artificial intelligence (AI) is an upcoming trend. However, less attention has been given to the construction of systems for Japanese novelists. In this study, we built "BunCho", AI supported story co-creation system in Japanese. BunCho's GPT-2 (an unsupervised multitask language model) trained using a large-scale dataset web texts and novels. With BunCho, users can generate titles synopses from keywords. Furthermore, propose interactive as tabletop role-playing game....

10.1145/3411763.3450391 article EN 2021-05-08

The gene F-box only protein 22 (FBXO22) has been discovered to promote the development of liver cancer tumors. Nevertheless, there remains considerable ambiguity regarding involvement FBXO22 in processes angiogenesis and metastasis hepatocellular carcinoma (HCC). Our study confirmed a significant upregulation expression both HCC samples cellular models. increased level correlates strongly with number tumors, presence vascular invasion, poor prognosis. Experimental investigations have shown...

10.1038/s41417-024-00861-w article EN cc-by-nc-nd Cancer Gene Therapy 2025-01-15

S-1, an oral multicomponent capsule containing tegafur, gimeracil, and potassium oxonate, has demonstrated efficacy in various tumor types. This study aimed to assess the pharmacokinetics, bioequivalence (BE), safety of a newly developed generic S-1 compared original brand-name formulation Chinese cancer patients under fasting fed conditions. A multicenter, randomized, open-label, single-dose, double-cycle crossover was conducted patients. The involved 120 subjects, with 60 assigned group...

10.3389/fphar.2025.1494902 article EN cc-by Frontiers in Pharmacology 2025-02-19

In this paper, we propose a dispatching strategy with charging plans upon the client requests for commercial fleet of pure electric taxis. To boost green industry, promoting development electrical vehicles is one most important policies many governments. new scenario that taxi fleets run as main transportation, traditional general gasoline taxis are no longer effective. It because those do not need to consider newly generated issues such endurance and related problems when them. addition,...

10.1109/ievc.2012.6183233 article EN IEEE International Electric Vehicle Conference 2012-03-01

Hemophagocytic lymphohistiocytosis (HLH) is a rare severe clinical syndrome. HLH manifesting during pregnancy has been paid much attention in recent years. Despite the specificity of pregnancy-related HLH, there not any consensus regarding its treatment. According to previous study, corticosteroid/IVIG mainstream therapy; however, efficacy controversial. Etoposide an important agent HLH-94 regimen; nevertheless, use limited because possible toxicity fetus. Methods: In this we summarized 13...

10.1186/s13023-019-1033-5 article EN cc-by Orphanet Journal of Rare Diseases 2019-02-18

Acute pancreatitis in pregnancy (APIP) is a rare and serious complication during pregnancy. It has acute onset difficult to diagnose treat. The aim of the present study was describe etiology, clinical manifestations, maternofetal outcomes APIP.

10.1186/s12884-022-04742-8 article EN cc-by BMC Pregnancy and Childbirth 2022-05-17

The unique clinical features of pregnancy termination in the second trimester with concurrent placenta accreta spectrum (PAS) disorders place obstetricians a complex and delicate situation. However, there are limited data on this rare dangerous condition. objective research was to investigate evaluate management strategies patient group.The medical records patients who were diagnosed treated our hospital from December 2005 2015 retrospectively reviewed.A total 29 included analysis. A...

10.1186/s12884-018-1935-6 article EN cc-by BMC Pregnancy and Childbirth 2018-07-11

Objectives: To identify the key points for improving severe maternal morbidity by analyzing pregnancy-related ICU admissions in Beijing. Design: This was a retrospective, multicenter cohort study. Setting: Three ICUs tertiary hospitals Patients: A total of 491 cases any trimester pregnancy or within 42 days delivery were reviewed between January 1, 2008, and December 31, 2016. Interventions: None. Measurements Main Results: Among obstetric (median Sequential Organ Failure Assessment score,...

10.1097/ccm.0000000000003355 article EN Critical Care Medicine 2018-07-30

Objective: The objective of this study is to identify the maternal and neonatal outcomes in women with placenta increta or percreta China.Materials methods: We retrospectively analyzed 2219 cases from 20 tertiary care centers China between January 2011 December 2015. All were diagnosed percreta, based on either intraoperative findings histopathological findings.Results: incidence progressively increased 0.18% 0.78% Compared increta, was strongly related serious adverse outcomes: postpartum...

10.1080/14767058.2018.1442429 article EN The Journal of Maternal-Fetal & Neonatal Medicine 2018-03-07

Morusin has been traditionally used for the treatment of Mycoplasma pneumoniae pneumonia (MPP), but underlying mechanism remains elusive. The present study aimed to explore by which morusin achieves efficacy on mycoplasma pneumonia. model was established in BALB/c mouse and effects were evaluated model. Compared with group, DNA amount M. decreased 24.6 ± 3.14% 47.6 6.78% low (20 mg/kg) high (50 groups, respectively (P<0.05). Moreover, led levels pro-inflammatory cytokines such as interleukin...

10.1042/bsr20190190 article EN Bioscience Reports 2019-06-01

Asthma belongs to chronic inflammatory respiratory diseases characterized by airway inflammation and remodeling. Circular RNAs (circRNAs) are promising therapeutic targets for various diseases, including asthma. In this work, we aim investigate the role of circular RNA Erb-B2 receptor tyrosine kinase 2 (circERBB2) during progression asthma.Human smooth muscle cells (ASMCs) were treated with platelet-derived growth factor BB (PDGF-BB) mimic cell The expression circERBB2, microRNA-98-5p...

10.2147/jaa.s326058 article EN cc-by-nc Journal of Asthma and Allergy 2021-09-01

ABCC1 belongs to the ATP-binding cassette (ABC) superfamily, which encompasses a total of 48 constituent members. has been shown be associated with growth, progression, and drug resistance various types cancer. However, impact on cancer immune infiltration pan-cancer prognosis rarely studied. Our comprehensive analysis unveiled elevated expression across cancers. overexpression consistently predicted unfavorable outcomes based TCGA data. Moreover, exhibited intricate associations diverse...

10.1016/j.tranon.2024.101882 article EN cc-by-nc-nd Translational Oncology 2024-01-29

Abstract Background Moyamoya disease (MMD) is a rare and complex cerebrovascular disorder characterized by the progressive narrowing of internal carotid arteries formation compensatory collateral vessels. The etiology MMD remains enigmatic, making diagnosis management challenging. MOYAOMICS project was initiated to investigate molecular underpinnings explore potential diagnostic therapeutic strategies. Methods employs multidisciplinary approach, integrating various omics technologies,...

10.1186/s41016-024-00358-3 article EN cc-by Chinese Neurosurgical Journal 2024-02-08

A spatial co-location pattern is a group of features, whose instances frequently appear in the same region. In association rule mining, recent effort has been to consider utility as new measure interests, by considering different values individual items utilities. this paper, we incorporate into mining through concept utility, and general framework for high patterns defined. Furthermore, define extended ratio present an Extended Pruning Algorithm (EPA) prune down number candidates can obtain...

10.1109/fskd.2015.7382010 article EN 2015-08-01
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